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SAN DIEGO (KGTV) -- Mayor Kevin Faulconer is among local leaders expected to leave for Mexico City Sunday morning. The trip, which includes Imperial Beach Mayor Serge Dedina, is meant to strengthen ties between the border. The mayors plan to discuss border infrastructure projects, pollution in the Tijuana River Valley and economic ties with leadership in Mexico. RELATED: Trump threatens to 'close' parts of US/Mexican border if Mexico doesn't immediately halt immigrationThe trip comes as President Trump said he would shut down the border with Mexico if the country doesn’t handle the wave of asylum seekers entering the U.S. The San Diego Regional Chamber of Commerce says shutting down the border would have severe consequences. “Our daily lives are effected by the border crossings and how long that takes. So we certainly wish that not to be something to be toyed with,” said Jason Wells, Executive Director of the San Ysidro Chamber of Commerce. The San Ysidro Port of Entry is the busiest land crossing in the U.S. with nearly 100,000 vehicles and pedestrians crossing every day. 1098

SAN DIEGO (KGTV) — In just days, Pfizer’s COVID-19 vaccine will go before a key group of scientific advisers to the Food and Drug Administration, and a San Diego doctor will be part of the process to cast an important vote.Dr. Mark Sawyer, an infectious disease specialist at Rady Children’s Hospital, will serve as a voting member of the Vaccines and Related Biological Products Advisory Committee or VRBPAC when the body meets Dec. 10 to publicly vet Pfizer’s COVID-19 candidate.Dr. Sawyer is also a professor of clinical pediatrics at UC San Diego. He has served before on this outside advisory committee to the FDA, but the stakes have never been so high.“I mean this is a tough decision,” he said in an interview Friday. “We're weighing the benefit of a vaccine against the risks. And with any new product, we don't know the risks and we have to estimate based on the data we have.”Dr. Sawyer said he received Pfizer’s full Phase 3 data Friday morning, making him one of the first Americans outside the FDA to see the full details of the company’s large-scale clinical trial. The FDA is expected to release the data to the general public by Tuesday, two days before the public meeting.Sawyer will be one of about 20 outside vaccine experts from around the country on VRBPAC. The FDA hasn’t yet released a full roster of the doctors and scientists who will take part. The independent advisory committee will hear comments from Pfizer and the FDA and listen to public input before voting on whether to recommend emergency authorization.The marathon meeting is expected to last up to nine hours.“The FDA counts on this advisory committee to be an independent group of people who are looking at the same information they looked at and asking us what our concerns are, or whether we reached the same conclusion that their staff have reached,” he said.The meeting comes on the heels of a study by Pew Research that found lingering skepticism of the vaccine. Just 60% of Americans planned to get vaccinated as of the survey released Monday.“I do think that's going to change once this committee meets and the data is made public and we can all talk together as a community about what we know about the safety, and what we don't know, frankly,” he said.Dr. Sawyer was a member of VRBPAC for four years and briefly served as the acting chair in 2017.The committee meets a few times each year to make recommendations on the annual flu vaccine and other drugs.The committee’s vote is not binding. The job of the outside advisers is to issue a recommendation and the FDA can overrule them, but the agency rarely does. From 2003 to 2019, VRBPAC made 105 recommendations. The agency fully implemented 84% of VRBPAC’s recommendations and partially implemented 10%, according to Union of Concerned Scientists.That means when the committee votes Thursday, it’ll carry a lot of weight. The FDA is expected to announce its final decision shortly after the vote, possibly within hours.Dr. Sawyer said the advisers will make a decision following the process they traditionally do, based on all the knowns and unknowns. “And we’re going to weigh that against what we're going through right now,” he said. “Our hospitals are getting overwhelmed. Our ICUs are getting full.”“We really need to do something to intervene and the vaccine is the best thing we've got going,” he added. 3369

SAN DIEGO (KGTV) - It’s the largest loss of life in United States Navy history and you can read an award-winning account of it by two San Diego authors. ‘Indianapolis: The True Story of the Worst Sea Disaster in U.S. Naval History and the Fifty-Year Fight to Exonerate an Innocent Man’ is being released as a paperback after the hardcover became a New York Times bestseller. Sara Vladic and Lynn Vincent wrote the book together after researching it for more than 17 years. “It’s so much more than a sinking story and a shark story,” said author Lynn Vincent. Vladic spent nearly two decades interviewing survivors from the sinking USS Indianapolis. “Getting to know these men and their story and heroism and what it took to survive those days is incredible,” added Vladic, “it still teaches us lessons today of what the cost of freedom really is and what we should be remembering.” The book is cinematically written and presents multiple accounts from the men that had to fend off sharks and each other for several days at sea after the heavy cruiser was sank by the Japanese during WWII. The authors say they are in talks with several streaming services to make a miniseries based on the book. 1202

SAN DIEGO (KGTV) -- It’s Safely Back to School week on ABC 10News and we’re talking about issues that impact education during this pandemic.As part of our ABC 10News San Diego Back to School Safely week, anchor Ben Higgins talked with local expert Lisa Smith, a parent coach, with advice on how to calm the chaos in your home. 334

SAN DIEGO (KGTV) -- In one San Diego neighborhood alone, around a half dozen residents have reported seeing rattlesnakes dangerously close to their front doors.The Department of Fish and Wildlife says avoid tall grasses and heavy brush if you can. And if your kids are playing in snake country — ditch sandals for a pair of boots.RELATED: Warm temps brings rattlesnake sightings across San Diego 408