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WASHINGTON, April 11 (Xinhua) -- Taking a statin before having major elective surgery reduces potentially serious kidney complications, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.Each year, more than 230 million major elective surgeries are performed around the world. Unfortunately, many patients who undergo major operations develop kidney injury soon after surgery, often due to decreased blood flow to the kidneys and/or the effects of inflammation.Animal studies suggest that the cholesterol-lowering drugs called statins protect the kidneys from such damage, but whether a similar benefit occurs in humans is uncertain. To investigate, Amber Molnar, University of Western Ontario, and colleagues conducted a population-based retrospective study of all older patients who underwent major elective surgery in the province of Ontario, Canada from 1995 to 2008. Surgeries included cardiac, thoracic, vascular, intra-abdominal, and retroperitoneal procedures.A total of 213,347 patients from 211 hospitals underwent major elective surgery, and 4,020 patients (1.9 percent) developed postoperative kidney injury within two weeks of surgery. A total of 1,173 patients (0.5 percent) required dialysis within two weeks of surgery, and 5,974 patients (2.8 percent) died within a month of surgery.Prior to surgery, 67,941 patients (32 percent) were taking a statin. Patients taking a statin were 20 percent less likely to develop kidney injury, need dialysis, and die compared to patients who were not taking a statin. Also, there was evidence of a dose-effect, with patients on higher potency statins having less kidney injury. In addition, statins were beneficial whether they were started greater than 90 days or less than 30 days prior to surgery."Our study suggests that statin use in older persons results in less kidney injury following major elective surgery and reduces the risk of premature death after surgery," said Molnar, adding that the results warrant further investigation with more rigorous studies, but such trials will be difficult to carry out.

BEIJING, Feb. 20 (Xinhua) -- Chinese Vice Premier Wang Qishan on Sunday called for sound and fast development of the nation's tourism industry as he called it a strategic pillar of the national economy.The tourism industry has huge potential, which needs further opening up, reform and innovation. Market should play a fundamental role in allocating the resources, Wang told a meeting of tourism work.He stressed the diversified needs of customers should be met, and the market order should be standardized to protect customer's legitimate rights."Local authorities should work together to make tourism a strategic pillar industry," he said.Wang also noted tour guide forces play a very important role in the industry development.More training should be arranged in the areas of professional skills and ethics, as well as response to emergencies.The wage and social security system of the work force should also be improved, he said.

JINAN, Feb. 3 (Xinhua) -- Chinese Premier Wen Jiabao on Wednesday and Thursday visited drought-hit villages and ordered all-out efforts to combat the dry spell while celebrating the Chinese New Year with local people.When visiting Jiaxiang County and Qufu City in east China's Shandong Province, Wen inspected cornfields and reservoirs to assess the drought's impact.The drought, which began in October, has hit the southwest parts of Shandong hardest."It's hard to know when it will rain. We must prepare for the worst and do our best to combat the drought to ensure a good harvest," Wen said while visiting a reservoir in Qufu.Wen made the remarks Wednesday afternoon after learning the reservoir was holding a volume of water 8 million cubic meters less than normal.He told officials accompanying him any drought-caused reduction in grain output may undermine the government's top priority for 2011: the stabilization of prices.Officials at all levels must work to combat the drought, Wen added.China's central authorities last week announced an ambitious water conservancy project development plan, to raise China's ability to control flooding and drought.Under the plan, the average annual government spending on such projects will double the 2010 level."The drought affects agricultural output, which is related to the nation's food security and the income of rural people. I worry about it," Wen told a local farmer Wednesday morning.In the evening, Wen joined Liu Xianglun, 77, and his family at their house to make dumplings to eat to welcome the Chinese New Year.Before visiting Shandong, Wen visited farmers and workers in Dabieshan Mountain area, an old revolutionary base in east China's Anhui Province.The Spring Festival, China's Lunar New Year, falls on Thursday.

BEIJING, May 11 (Xinhuanet) -- New retirees suddenly confronted with plenty of time on their hands might be happy to learn that reading keeps one mentally alert and abreast of current aff airs, says Ursula Lenz of Germany's working group of senior citizens' organizations, BAGSO.Growing old can present difficulties such as failing eyesight or problems concentrating, but experts encourage the elderly not to give up on reading and to adapt to their situation.From the perspective of health professionals, there are many advantages to reading books or newspapers for senior citizens.Reading helps the elderly keep a sharp mind. The ability to transform words into mental images is good for cognitive performance. Reading also improves vocabulary, language use and the ability to concentrate, according to Simone Helck from the Kuratorium Deutsche Altershilfe, an organization in Germany that helps promote and develop strategies for taking care of the elderly.So, what exactly happens in the brain when we read?"The brain builds new synapses, junctions between the neurons, when it's stimulated such as during reading," says Manfred Gogol, a physician and president of Germany's Society for Gerontology and Geriatrics.Gogol recommends reading books that deal with subjects that are of special interest to the reader. If a long novel seems like too much work, then try a novella or collection of short stories.But a prerequisite for reading is that any sight defect is corrected by an optician.In response to the needs of elderly people, publishers print books with large typefaces and bigger line spacing. Lenz says it is worthwhile asking for large print books in libraries and bookshops.But no matter what the reading matter is, another important aspect is being able to exchange opinions about a book with other people. Whether it's a society magazine, highbrow literature or a daily newspaper, there is always something to talk about.

WASHINGTON, April 6 (Xinhua) -- A study led by researchers at the University of Michigan (U-M) showed in animal studies that new cancer drug compounds they developed shrank tumors, with few side effects.The study, done in two mouse models of human cancer, looked at two compounds designed to activate a protein that kills cancer cells. The protein, p53, is inactivated in a significant number of human cancers. In some cases, it is because another protein, MDM2, binds to p53 and blocks its tumor suppresser function. This allows the tumor to grow unchecked. The new compounds block MDM2 from binding to p53, consequently activating p53."For the first time, we showed that activation of p53 by our highly potent and optimized MDM2 inhibitors can achieve complete tumor regression in a mouse model of human cancer," says lead study author Shaomeng Wang, director of the Cancer Drug Discovery Program at the U-M Comprehensive Cancer Center.Wang presented the study Wednesday at the American Association for Cancer Research 102nd annual meeting.Many traditional cancer drugs also activate p53 but they do so by causing DNA damage in both tumor cells and normal cells, causing side effects. These new MDM2 inhibitors activate p53 while avoiding the DNA damage common with other drugs. In this study, which was done in collaboration with Ascenta Therapeutics and Sanonfi-Aventis, researchers showed that these new drugs shrank tumors without significant side effects.Because p53 is involved in all types of human cancer, the new drug has potential to be used in multiple types of cancer. Further, the researchers also identified certain markers in tumors that predict which ones will be particularly sensitive to the MDM2 inhibitor, which would allow physicians to target the drug only to patients most likely to benefit.