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SINGAPORE, Sept. 7 (Xinhua) -- Singapore scientists have found possible new ways to treat a type of aggressive breast cancer that is unresponsive to current forms of treatment, local broadcaster Channel NewsAsia reported on Wednesday.The team of scientists at the Genome Institute of Singapore ( GIS) and National University of Singapore (NUS), led by GIS senior group leader Qiang Yu, found that the enzyme EZH2 acts by inhibiting genes that stop the growth of tumors in the body.The insights could open the door to developing more effective treatment for fast spreading breast cancers, especially the estrogen receptor-negative breast cancer that is common all over the world.It was also found that through EZH2, cancer is promoted in the body by activating specific genes that impact breast cancer progression and cancer stem cell self-renewal.Yu said the new understanding on how EZH2 works as a cancer- causing gene in breast cancer has important therapeutic implication."The results suggest that small molecule drugs that block enzyme activity of EZH2 may not work for cancers caused by EZH2's activation genes," Yu said.Currently pharmaceutical companies have been developing drugs only to the block EZH2 enzyme activity so that tumor suppressers can perform their protective role in blocking cancer growth.Researchers said the next step would be to develop biomarkers to identify tumors with EZH2.This step would enable better treatment methods, with one of options being the development of therapies that shut down EZH2 completely and not just inhibit its enzymatic function.The findings have been published on the journal Molecular Cell.

BEIJING, May 31 (Xinhuanet) -- European anti-trust regulators Monday launched in-depth probes into takeover bids for two Asian companies by two American peers in the computer hard disk drive sector, media reports said Tuesday.U.S.-based Seagate Technology has said it wants to buy Samsung Electronics Co's loss-making hard disk drive unit for 1.4 billion U.S. dollars -- a deal that will give Seagate access to Samsung's NAND-type flash chips for its solid-state drive products.Western Digital plans to purchase Hitachi Ltd's hard disk drive business for 4.3 billion dollars to give it an edge in developing next-generation storage technology.The two planned acquisitions in a sector with just five manufacturers worldwide have raised concerns in Brussels, the European Commission said."Hard drives are the backbone of the digital economy," said EU competition commissioner Joaquin Almunia in announcing the investigation."The sector has already experienced significant consolidation and the proposed acquisitions will further reduce competition."Brussels officials have until Oct. 10 to decide what action if any they will take.

BERLIN, June 8 (Xinhua) -- German health minister Daniel Bahr expressed cautious hope Wednesday for an end to the wave of E. coli infections as authorities reported two more deaths and more than 300 new cases."I can't give an all-clear, but after the analysis of the latest data we have reasons for hope, as the number of new infections is continuously dropping," Bahr told local public television ARD before an emergency meeting in Berlin with European Union Health Commissioner John Dalli."Unfortunately, there will be new cases and more deaths have to be expected, but overall new infections are clearly going down," he said.On the same day, Germany's national disease control center, the Robert Koch Institute, said the number of reported cases in Germany had risen by more than 300 to 2,648. Nearly 700 of those affected have been taken to hospital with a serious complication that can cause kidney failure.The Institute did not fully support Bahr's optimism. It said there was a declining trend in new cases but added it was not clear whether this was because the outbreak was truly waning or because consumers were staying away from the raw vegetables believed to be the source of the E. coli.The German government has faced increasing criticism from abroad and at home over its dealing with the crisis. It was twice wrong in naming the source of the outbreak and it has been criticized for a lack of coordination between research institutes.Dalli was quoted by local daily Die Welt as saying, "we have to rely on the experience and expertise across Europe, and even outside Europe."The Max Planck Institute for Infection Biology in Berlin also called for a federal government representative to coordinate the various government agencies dealing with the disease to eliminate mixed messages.