武清区龙济好(武清龙济治疗男性不育症) (今日更新中)

SAN DIEGO (KGTV) - The cost of living in San Diego doesn’t always make it easy for local families to take vacations. Hotels and home rentals can drain a family’s savings. 10News reporter Jennifer Kastner found a local family that’s able to go jet setting without breaking the bank, thanks to a home exchange network.Dana Fallentine, her husband, and their four kids have been taking incredible vacations at an impressive savings. “[We’re talking] thousands and thousands and thousands of dollars,” she tells 10News. Fallentine found the website Love Home Swap, which connects users with homeowners around the world. Arrangements can be made to do temporary home trades.The fee is 0 a year. Compare that to the most recent average U.S. hotel price, which is 0 a night, according to Statistica. Members can swap homes or use points to stay in rental homes. Type in where you want to go and when. Browse the options to see photos and amenities, and then start chatting with the owner. For privacy and security, Love Home Swap does ID verification. For protection, phone numbers, email addresses and home addresses are not made visible on the website.The Fallentine family's most memorable experience was from a swap they did with an Italian family. The Italians got to the Fallentine's home the night before the Fallentine's flew off to the Italians' home in Rome.“I took them to Costco. They bought all this food and then they said, ‘Oh, we're going make you guys dinner.’ I’m like, ‘Totally! I’m not going to pass up a meal by real Italians. I mean, that's crazy!’”Fallentine says when her own family home-swaps, having access to another home’s kitchen is one of the biggest cost-savers.“If you're thinking about the food aspect, just to be able to cook your own food is amazing and [you have a] full kitchen with everything you need,” she adds.Another perk is having access to a home's laundry room. It allows the Fallentines to save on airline baggage fees, because now they can carry-on backpacks and wash their clothes at the vacation homes. For a family wanting to live large on a small budget, she says Love Home Swap has been a game changer. “It saves money. It’s just common sense, basically,” says Dana. 2235

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

SAN DIEGO (KGTV) – The American Red Cross of San Diego/Imperial Counties opened a shelter Thursday night for residents displaced by flooding from heavy rainstorms.The shelter opened around 9:30 p.m. at the Paradise Valley Seventh-day Adventist Church on East 8th Street in National City.Services include a safe and clean place to stay, food, hydration, comfort kits with personal hygiene items, emotional support and health services, according to the Red Cross. The shelter will stay open as long as there is a need.In response to the flooding caused by today’s rainstorms, #RedCross disaster workers are working to open a shelter this evening at the Paradise Valley Seventh Day Adventist Church (2701 East 8th Street, National City, CA 91950). The shelter is anticipated to be open by 9:30 p.m.— SDIC Red Cross (@SDICRedCross) December 7, 2018 852

SAN DIEGO (KGTV) - The family of a man killed in 2013 is pleading with the community for new leads as the case has now been left unsolved for more than half a decade.Ralph Green was killed on October 20, 2013.  He was murdered on Jewell Street in the Mountain View neighborhood, on the porch of his daughter’s home while at her 32nd birthday party.His daughter, Chanel Green, says the shooting happened suddenly, catching everyone by surprise.“My mother was on her way outside, so it was a blessing I didn't lose both my parents that day,” Chanel said. “I remember (my mother) shrieking, ‘oh my god, Ralph’s been shot.’ And I ran to the door to see my dad walk holding his neck.”Green says he was shot three times, once through this throat.“My brother catches him, and I moved my brother out of the way, and I laid (my father) down on the ground, and I start screaming, “oh my god, my dad’s been shot, call the police,’” she said. “My dad bled out on the floor, and all I could hope was that he heard me when I told him I loved him.” Channel’s aunt, Jennetta Pierce, was also shot.  Pierce is Ralph’s cousin-in-law.Pierce says she was inside the house, by the window, when the bullets started flying. One of them hit her on the lower back.“I got hit, but I didn’t let anyone know I got hit because my kids were there, and I just told them to get up under the table,” Pierce recalled.  After that, emergency crews came inside the house and took her to the hospital, where she spent two weeks.  She says she spent the next five years focused on moving forward.Police have said the shooting was random.  Chanel says there have been tips, and potentially leads given to the police but none have panned out.  But she’s convinced that there are people out there that know something, that can give her and her family the closure they need.“For anybody who knows somebody that knows something to come forward, now is the time, to tell the truth,” Chanel said. Anyone with information can contact San Diego Police or Crime Stoppers at 888-580-8477. 2087

SAN DIEGO (KGTV) -- The families of three children who contracted E. Coli during visits to the San Diego County Fair this summer have filed claims against the company that operates the fair.Attorneys representing the families of Jedidiah King Cabezuela, Cristiano Lopez, and Ryan Sadrabadi filed legal documents on Monday."Our investigation has already turned enough information for us to determine that these illnesses were entirely preventable," said Ron Simon, one of the attorneys representing the families.County of San Diego Health and Human Services Agency confirmed 11 cases of E. Coli, all of which involve children ranging in age from two to 13. The outbreak was traced to children that visited the animal areas or the petting zoo, or had other animal contact at the fair, county health officials previously reported, and that the illnesses had no link to any food facilities the children accessed.2-year-old Jedidiah King Cabezuela, from National City, suffered stomach problems four days after visiting the fair on June 15 despite washing his hands following a stop at the petting zoo, a family member told 10News. E. Coli can incubate over a period of 10 days.Over the next three days, Jedidiah was in and out of the emergency room before the symptoms worsened. His kidneys began failing, and he died from Shiga-toxin-producing E. Coli June 24.On June 28, fair officials closed public access to all animal areas at the livestock barn on the eastern side of the Del Mar Fairgrounds."The Cabezuelas, the Lopez's, and the Sadrabadis took their families to the fair expecting to have a good time," said Ben Coughlan of Gomez Trial Attorneys. "No family should have to be concerned about their children getting sick, or worse, at a Fair geared towards attracting families and children."Officials with the 22nd District Agricultural Association, the company that runs the fair, said they anticipate the animal exhibit to return with more safeguards and policies next season. Personnel currently reminds guests to wash hands before and after the exhibits and requires guests leave strollers out of walkways between animal pens, the fair said.While most people who contract the E. Coli bacteria do not develop severe complications, roughly 5 to 10% of those who do can develop a potentially life-threatening kidney infection. Symptoms do not appear for three to four days after contraction and can include severe abdominal cramps, watery or bloody diarrhea and vomiting.People who do not wash their hands after petting an animal, or bring food or drinks into an area with animals, increase their chance of getting sick, CDC officials said.The CDC has recommendations for keeping children safe around animals: Don't let children sit or play on the ground in animal areasTeach children not to put their fingers or objects near an animal's mouthDon't let children put their hands or fingers in their mouths when they're in an animal area 2948

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