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SAN DIEGO (KGTV) — Researchers at the University of California, San Francisco are working on a spray designed to block the novel coronavirus from hijacking cells in the body, like a biological mask or internal personal protective equipment.They’re doing it by borrowing a defense mechanism from an unlikely source: llamas.The team, led by UCSF graduate student Michael Schoof, engineered a synthetic molecule based on one found in a llama’s immune system that acts like an antibody but is one-tenth the size.Human antibody treatments, known as convalescent plasma, require a transfusion in a hospital setting. But this smaller molecule, called a nanobody, can be easily self-administered via an inhaler or nasal spray and rapidly manufactured using yeast, Schoof said.The scientists named their product AeroNabs. They say it could be an inexpensive intervention for treating and preventing COVID-19 while the world waits for a vaccine.“We don't know how effective vaccines will be. We don't know how long it will take to rapidly deploy them, so we envision this product as hopefully a bridge until there is widespread, effective vaccination,” Schoof said.Once a vaccine is available, AeroNabs could offer protection for individuals who are unable to be inoculated for health reasons, he said, or an early treatment option.The team is in talks with commercial partners and hopes to begin clinical trials soon.In the 1980s, Belgian scientists discovered that about half of the antibodies in camels, llamas and alpacas are shaped differently than the antibodies found in other mammals, including humans. Researchers later learned they could use a fragment of these oddly shaped camelid antibodies to bind to antigens.Those fragments are called nanobodies.Currently, there is only one FDA-approved drug that uses nanobodies. Caplacizumab was approved last year to treat a rare blood disorder.The team at UCSF sifted through billions of nanobodies to find one that binded best to the spike proteins on the coronavirus, then engineered it to stick even better.The coronavirus uses its spikes to enter cells and replicate; the spikes are essentially the pathogen’s key into the body. By coating the spikes with nanobodies or antibodies, the viral key no longer fits into the body’s receptors and the virus can’t get in.“This works in the lab. It needs to be translated into the clinic,” said Schoof.The team at UCSF still needs to figure out the best delivery method, whether it is a nebulizer, an inhaler or a nasal spray. 2524

SAN DIEGO (KGTV) - San Diego is giving dockless scooters and bikes preferred parkingThe city is in the process of installing 330 rideshare scooter and bike spaces throughout downtown. The first few of them have been spotted in Cortez Hill. “I think it’s smart,” said Carlos Navarro who work at a restaurant in the Gaslamp “they drive by our store — running into the customers or hit the cars that are parked.” The city says the spaces are being placed at red zones where cars cannot park. “It’s not going to be as crowded or cluttered,” said scooter rider Autumn McFeeley, “the city must really like them.” A class action lawsuit was filed against the city earlier this year claiming San Diego has failed to maintain pathways for people with disabilities. “Allowing there to to be safe storage and parking for those vehicles off the sidewalk is a much better approach, said Colin Parent with Circulate San Diego, “it’ll help minimize those kinds of conflicts” The city of San Diego says more information will be made available about this project in coming days. 1069

SAN DIEGO (KGTV) - San Diego drivers will have more opportunities to take care of driver’s license renewals and vehicle-related needs thanks to longer hours at California Department of Motor Vehicles offices. Starting Monday, 69 offices will be open for customers at 7 a.m., four days a week. On Wednesdays, the offices will open at 9 a.m. The DMV is offering extended service due to the high demand for Real ID compliant drivers licenses.The early hours will be available in San Diego County at the following DMV locations: El CajonOceansidePowaySan Diego (Hillcrest)San Diego (Clairemont)San Ysidro The Chula Vista DMV office has had extended hours since last summer. Saturday service is also available from 8 a.m. to 5 p.m. in Chula Vista, Poway, and Clairemont. 773

SAN DIEGO (KGTV) -- San Diego Police are asking for the public’s help finding a man who went missing early in the day Wednesday. According to police, 77-year-old David McArthur left his home on the 7900 block of Wing Span Drive around 10 a.m. to work on his boat at The Southwestern Yacht Club. He was last seen walking toward his vehicle in the parking lot of the yacht club, according to a family friend. McArthur was diagnosed with Alzheimer’s six years ago. McArthur is described as a white man, 77-years-old who is bald with grey hair on the sides and a thin build. Police say he also wears a yellow metal wedding ring and black band digital watch on his left wrist. McArthur is from New Zealand and speaks with a slight accent. He drives a 20907 Infinity G35 two-door coupe with California license plate 5XMW652. Anyone with information is asked to call the San Diego Police Department at 619-531-2000. 917

SAN DIEGO (KGTV) – San Diego County is working to make it easier for San Diegans to get flu shots, which health officials say is especially important this year because of the coronavirus pandemic.On Thursday, local leaders kicked off efforts to promote flu vaccinations. Over the course of the next few weeks, they will be hosting pop-up clinics across the county where people can get free flu shots.The pop-up clinics are designed for those who don’t have insurance or those who can’t get the vaccine from their health care provider or pharmacy.Valentina Christiansen came to one of the clinics to get flu shots for her family. She said, “I think it’s great because I tried to go through our health plan and that’s over a month out, and we wanted to get it sooner. We heard about the opportunity and we’re excited to be able to do that.”Dr. Denise Foster, chief nursing officer for the county, said getting the flu vaccine can also help in the battle against the coronavirus. Keeping flu patients out of the hospital frees up beds and resources for those fighting COVID-19.“The flu vaccine can prevent the flu and prevent people from seeking health care services that might be needed right now connected to the pandemic,” Foster said.Foster added there are more people that have gotten the flu vaccine this year in comparison to this same time last year. They’re hoping this trend continues.Free flu shot clinics will take place on specific dates at these locations:Saturday, Oct. 24 at South Public Health Center, 690 Oxford Street, Chula VistaTuesday, Oct. 27 at North Coastal Public Health Center, 3609 Ocean Ranch Blvd, OceansideWednesday, Oct. 28 at Central Public Health Center VIP Trailer, 3177A Oceanview BlvdThursday, Oct. 29 at East Public Health Center, 367 N. Magnolia Avenue, El CajonTuesday, November 3 at North Inland Public Health Center, 640 W. Mission Ave #2, Escondido 1896

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