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WASHINGTON, Oct. 9 (Xinhua) -- U.S. researchers have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions. In their report receiving early online publication Sunday in Nature Biotechnology, researchers describe using small interfering RNA technology to silence the biochemical signals that attract a particular group of inflammatory cells to areas of tissue damage."The white blood cells known as monocytes play a critical role in the early stages of the immune response," says Matthias Nahrendorf, of the Massachusetts General Hospital (MGH) Center for Systems Biology, the paper's senior author. "We now know there are two subsets of monocytes -- an inflammatory subset that defends against pathogens and a reparative subset that supports healing. But if the inflammatory response is excessive, it can block the healing process and exacerbate conditions such as heart disease and cancer."Cells damaged by injury or disease release a cocktail of chemicals called cytokines that attract immune cells to the site of the damage. Inflammatory monocytes are guided to sites of tissue injury by a receptor protein called CCR2, and the MGH-led team devised a strategy targeting that molecule to block the inflammatory process but not the action of the reparative monocytes.Small interfering RNA (siRNA) technology prevents production of specific proteins by binding to associated messenger RNA molecules and preventing their translation. However, the technique requires extreme precision in developing the right siRNA molecule and delivering it to the correct cellular location.To make sure that their siRNA preparation targeted the right monocytes, researchers first confirmed that its use reduced levels of CCR2 in monocytes and increased levels of the fragments produced when siRNA binds to its target. They then showed that monocytes from mice treated with the siRNA preparation were unable to migrate towards CCR2's usual molecular target. Experiments in animal models of several important diseases showed that the siRNA preparation reduced the amount of cardiac muscle damaged by a heart attack, reduced the size and the number of inflammatory cells in atherosclerotic plaques and in lymphomas, and improved the survival of transplanted pancreatic islets."These inflammatory monocytes are involved in almost every major disease," Nahrendorf explains. "Anti-inflammatory drugs currently on the market hit every inflammatory cell in the body, which can produce unwanted side effects. This new siRNA treatment doesn't affect inflammatory cells that don't rely on the CCR2 receptor. That makes a big difference."

NANJING, Dec. 8 (Xinhua) -- Chinese stargazers will have their best view of a total lunar eclipse in 10 years on Saturday if weather permits, the Zijinshan Astronomical Observatory under the Chinese Academy of Sciences (CAS) said Thursday.Wang Sichao, a research fellow with the observatory, said during the total eclipse, the full moon will not completely disappear from the Earth's shadow, but will take on a brilliant bronze color.He said the eclipse will be the best one seen in China since the last one occurred on Jan. 10, 2001."Theoretically, viewers can observe the eclipse from nearly everywhere in the country on Saturday," said the astronomer.He said the eclipse, the second this year, will last for 51 minutes. It will start at 8:45 p.m. and reach its climax at 10:06 p.m.Wang said Chinese viewers will have to wait until Oct. 8, 2014 to see the next total lunar eclipse.

ADDIS ABABA, Nov. 2 (Xinhua) -- Ethiopia will host the 13th World Congress on Public Health (WCPH) in April 2012, the Ethiopian Public Health Association (EPHA) said on Wednesday.The meeting will be held on April 23-27 under the theme: "Moving towards Global Health Equity- Opportunities and Treats".Speaking on the 22nd annual meeting of EPHA held here on Wednesday EPHA President Tewabech Bishaw said about 3,000 participants, including public health students from all over the world are expected to take part in the meeting.He said that preparations are well underway to successfully conduct the meeting.

BEIJING/CHONGQING, Oct. 16 (Xinhua) -- A team of Chinese and American scientists have discovered the world's only evidence of co-existing human beings and dinosaur tracks in a remote county in southwest China's Chongqing Municipality, according to a paper published Saturday in the Geological Bulletin of China, a Chinese core academic journal.Qijiang County's Lianhua Baozhai, which means "Lotus Mountain Fortress" in Chinese, has a large number of dinosaur tracks as well as a well-preserved fortress and historical epigraph, forming a direct line of evidence that ancient Chinese people built a residence and lived there for a long time, said Xing Lida, one of three researchers with the project as well as a doctoral degree candidate with the Department of Biological Sciences of the University of Alberta in Canada.Chinese people could have lived here for more than 700 years, and the mud cracks, ripple marks and duck-billed dinosaur tracks were considered by them to be lotus leaf veins, water environment and lotus, respectively, which is why they named it the Lotus Mountain Fortress, Xing Lida told Xinhua."Research shows that dinosaur tracks impacted ancient Chinese place names and folklore, so place names and folklore can be major clues for us in tracing dinosaur tracks," Xing said.According to the paper, the Lotus Mountain Fortress dinosaur tracks, the largest track group of cretaceous dinosaurs in southwestern China, contains 350 to 400 footprints that had been preserved in many ways, including concave footprints, convex footprints and multilayered footprints.

BRATISLAVA, Dec. 22 (Xinhua) -- The Slovak Education Ministry on Thursday launched an internet website to provide the general public with digitalized textbooks.According to Education Minister Eugen Jurzyca, the public could access a total of 26 digitalised textbooks, compulsory-reading books and download 65 audio-recordings on the website of eaktovka.sk.The word aktovka means schoolbag in Slovak."We hope that pupils will be able to study even in places where they don't bring their textbooks, such as during the holidays at their grandma's, but also that teachers will have an easier time putting together various textbooks or their sections on, for example, physics or chemistry," said the minister.Jurzyca said he estimated that 92 percent of households with school-age children which own personal computers and 70 percent of those which have access to the internet would visit the website.