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LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283
Keisha Lance Bottoms, Atlanta’s Democratic mayor who has seen a rise in her national profile in recent months, said Monday she has tested positive for COVID-19.Bottoms said she is not experiencing any symptoms from the virus.The Associated Press, among other outlets, have reported Bottoms is under consideration by Joe Biden to be his running mate this fall in the presidential election. Bottoms’ national profile has increased amid national unrest following the death of George Floyd on Memorial Day.Last month, Atlanta had an incident of its own as an Atlanta Police officer shot and killed Rayshard Brooks, who was attempting to flee from officers from an arrest in a Wendy’s parking lot. Bottoms was forced to respond to increased unrest in the city, and the firing of the officer involved in the incident.Despite the COVID-19 diagnosis, she continued to do on-camera interviews via webcam with news agencies, including CNN on Monday.“COVID-19 has literally hit home. I have had NO symptoms and have tested positive,” Bottoms tweeted Monday afternoon. 1064
Jill Biden wraps a day of the campaign on behalf of her husband, Joe with a Minnesota "Women for Biden Get Out The Vote" Rally in Minneapolis. WATCH RECAP:Jill Biden was joined by Minnesota Lt. Gov. Peggy Flanagan, US Senator Tina Smith, and several other female candidates for local and statewide offices. 314
JAMUL, Calif. (KGTV) - A Jamul family is mourning the loss from COVID-19 of a former little league coach and employee at Taylor Guitars.Greg Denny came down with a sinus headache in the second week of June. A trip to the ER revealed double pneumonia. Then came a positive COVID-19 test and fever, before his wife Kim brought him back to the hospital.“Five days of fever, hadn't been able to break it. He was at 102°,” said Kim Denny.A week after Greg was admitted, he was placed on a ventilator.“It was very emotional, like a roller coaster. Good one day and then things changed that same day,” she said.Eventually, the bad days took over. His kidneys failed. So did his pancreas. Then he got a blood infection. Last Friday, Greg — an Army veteran, father of two and grandfather of four — passed away at the age of 48.“He was my soulmate, my best friend and now he's my guardian angel,” she said.Kim calls her husband a wonderful dad and grandfather.“He’s the best man I’ve ever known,” said Dillon Wulff, Greg’s adult son.For the last five years, Greg has worked in security at Taylor Guitars. For more than two decades, he has coached or volunteered for little league games in Spring Valley.In her time of grief, Kim takes comfort in the daily game they played called, "I love you more."“Whoever said it first would win. So constantly, he'd get up and say, ‘I love you more.’ I'd get up and say, ‘I love you more,’" said Kim.They would play that game until the day he went on the ventilator.As for where the origin of the COVID-19, she has no idea. He always wore masks.“My husband was very safe … So, it’s scary. People need to take every precaution that they can,” said Kim.Greg did have an underlying condition: high blood pressure. A Gofundme campaign has been set up to help his family with expenses.Taylor Guitars issued the following statement:“Everyone at Taylor Guitars is heartbroken by the loss of Gregory Denny. For the last 6 years, he came to work with a smile, bringing joy and professionalism to his job. Today Taylor is safer and better equipped to handle emergency situations because of Gregory’s leadership as our security specialist. He was a great co-worker and friend, and we will all miss him.” 2227
JACKSON, Miss. — Mississippi legislators have voted to remove a Confederate battle emblem from their state flag. Mississippi’s House and Senate voted Sunday to retire the flag adopted in 1894. It's the last state flag that includes a Confederate symbol that many people condemn as racist. Republican Gov. Tate Reeves has said he will sign the bill. The change comes amid widespread protests over racial injustice. Mississippi has a 38% Black population. A commission would design a new flag that cannot include the Confederate symbol but must have the words “In God We Trust.” Voters will be asked to approve the new design in the Nov. 3 election. 655