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SAN DIEGO (CNS) - The Collaborative Clinical Trials Unit at UC San Diego has been selected to lead and administer an international seven-year, million grant for HIV/AIDS clinical trials.The National Institutes of Health selected UCSD, along with other American, South African and Indian research hospitals, as part of its seven-year HIV/AIDS funding renewal. Every seven years, NIH competitively renews its funding of the HIV clinical trials networks operating in the United States and internationally.During the current application process, the UC San Diego AntiViral Research Center, University of Colorado Hospital, Houston AIDS Research Team and Durban International clinical research sites were chosen to work collaboratively on research priorities for the NIH/National Institute of Allergy and Infectious Diseases HIV/AIDS Adult Therapeutics Clinical Trials Network.The Chennai Antiviral Research and Treatment Center, University of Southern California and University of Miami clinical research sites were also chosen to join UCSD to serve as qualified reserve or protocol-specific sites as needed for future clinical trials."UC San Diego has helped shape HIV/AIDS research and treatment through innovative research since the inception of the adult and pediatric therapeutic clinical trials networks in 1986," said principal investigator Dr. Constance A. Benson, director of UCSD's Antiviral Research Center."Together, the seven clinical research sites selected by the NIH for the HIV therapeutic clinical trials network bring together a wealth of scientific expertise, experience and the high quality performance required to conduct complex clinical trials," she said.Abouty 38 million people are living with HIV/AIDS globally, with 1.7 million acquiring HIV in 2019 alone. In the United States, 1.2 million people are living with the virus.The UCSD-led clinical trials unit serves several regions in the United States burdened by chronic and new HIV infections as well as global regions impacted by both HIV and tuberculosis.The unit will investigate therapeutic strategies aimed at a cure for HIV, including evaluating viral persistence, researching antibody approaches to treatment and prevention and investigating treatment of inflammation and its impact on HIV comorbidities.In addition, investigators will study new drugs including long-acting drug formulations for HIV treatment and prevention, HIV-related coinfections and comorbidities -- including metabolic and end organ complications and a hepatitis B cure, as well as the treatment and prevention of tuberculosis, including TB preventive vaccines, in persons with mono- and HIV-coinfection."We are honored to lead a talented pool of investigators in a common goal of advancing research that clinically benefits people living with HIV," Benson said. 2830

SAN DIEGO (CNS) - Power outages left tens of thousands of homes and businesses across San Diego without electrical service Tuesday.The first of the two blackouts began for unknown reasons about 11:15 a.m., affecting Fort Rosecrans, Lindbergh Field, Marine Corps Recruit Depot, the Midway area, Mission Bay, Ocean Beach, Pacific Beach, Point Loma and Sunset Cliffs, according to San Diego Gas & Electric.In all, the outage left about 13,000 utility customers without electricity, SDG&E reported.Repair crews had power restored to all the affected areas as of 12:30 p.m., according to the utility company.About 90 minutes later, another outage took place to the east, knocking out electrical service to roughly 8,300 addresses in Balboa Park, Center City, Chollas Creek, City Heights, Golden Hill, Normal Heights, North Park, Oak Park and University Heights, SDG&E reported.The utility predicted restoration of power to those neighborhoods by late afternoon. 976

SAN DIEGO (CNS) - San Diego County supervisors voted Tuesday for Dianne Jacob to serve as board chairwoman, and approved Greg Cox as vice chairman.By a 5-0 vote, the board also voted in Jim Desmond as the chair pro tem. Desmond, who succeeds Bill Horn as District 5 representative, made a motion for the leadership change based on the board rotation policy.The vote came after outgoing board Chairwoman Kristin Gaspar made a short speech on her time in the leadership role.She cited numerous board accomplishments, including the formation of working groups on the regional homeless problem and county road policies."This year has been incredible," Gaspar said. "It's sad to pass along the gavel, but at the same time, I'm happy." 737

SAN DIEGO (CNS) - The San Diego Association of Governments released a report Wednesday showing that bicycle ridership in the county is up more than 40% from 2019, since the statewide stay-at-home order due to COVID-19.Since the start of the order, SANDAG has tracked data to understand how the COVID-19 pandemic has impacted travel in the San Diego region.The data show that with more people staying closer to home, the choice to use alternative transportation for shorter trips, including outdoor opportunities for recreational and fitness activities, continues to increase.The report, titled "Bike Riding in the San Diego Region Since COVID- 19," examines bike volumes on eight corridors around San Diego County between mid-March and mid-August 2020, compared to the same period in 2019. The report also shares biking insights from residents and their plans to continue riding.From April 18 to May 17 -- "Month 2" in SANDAG's data set -- bicycle traffic was up a whopping 66% from 2019, with Month 3 just behind at 62%. As the weather began to heat up and more people headed back to work in their vehicles, the numbers dropped considerably in months 4 and 5, with bicycle traffic volume up 28% and 22% from the previous year.Since 2012, SANDAG has monitored bike travel through counters on the regional bikeway network that measure change in bike volumes over time with continuous counts collected and transmitted every 15 minutes.Since the start of the stay-at-home order, daily volumes increased an average of 42% across the network during the five months in 2020, compared to the same time in 2019.Additionally, biking volumes were up the most on weekends over the five-month period at 53%, compared to weekdays at 35%. Individual corridor increases ranged from 12% on the Landis Street corridor to 62% on the Inland Rail Trail and Mission Road corridor. A total of 84% of residents surveyed who said they were biking more since the pandemic began said they expect to continue biking even when restrictions are lifted.In light of the current public health crisis and in recognition of National Bike Month in May, SANDAG created a new pilot program to support local jurisdictions by giving them the opportunity to designate temporary roadway modifications that create safe spaces for people to bike, walk, run, scoot, use a wheelchair and move during the pandemic.SANDAG awarded 11 jurisdictions funds to help implement temporary Shared Streets pilot projects. The jurisdictions awarded proposed a range of activities such as closing residential streets to through traffic, enhancing signage to alert vehicles of shared streets conditions and closures and creating space for local business patrons to walk, bike and dine outside while maintaining physical distance. 2777

SAN DIEGO (CNS) - The San Diego Blood Bank reached out to the public Tuesday asking for blood donations amid the coronavirus pandemic.The fast-spreading respiratory illness has resulted in school closures and work-from-home policies throughout San Diego County, forcing the bank to cancel blood drives.The San Diego Blood Bank collects more than half of its blood supply on bloodmobiles stationed at these blood drives, according to the company.RELATED: Red Cross pleads for blood donations amid severe shortage due to COVID-19 cancellations"The U.S. is on the verge of a serious blood shortage that will lead to blood rationing and triage," said David Wellis, CEO of San Diego Blood Bank. "We need healthy people to come out to donate immediately. Supplies are dropping to critical levels."Individuals are not at risk of contracting the coronavirus from donating blood, and the virus poses no known risk to patients receiving transfusions, officials said."It's safe to donate blood," said Admiral Brett Giroir, Assistant Secretary of Health. "Part of preparedness includes a robust blood supply."RELATED: San Diego to legally enforce new public health orders over coronavirusAs a safety precaution, San Diego Blood Bank is currently deferring people who have traveled to areas with World Health Organization level 3 travel notices (China, Italy, Iran, South Korea, France and Spain, among others) for 28 days from their date of departure from the outbreak area. If donors have been exposed to or treated for coronavirus, they are also deferred for 28 days. People experiencing coronavirus symptoms, including fever, cough and shortness of breath, should not attempt to donate."It's important to note that blood collection activities are not `mass gatherings,' rather they are controlled blood drives conducted using appropriate infection control mechanisms intended to assure the safety of the products, donors and staff," said Doug Morton, COO of San Diego Blood Bank. "San Diego Blood Bank is highly regulated and is following best practices, such as properly cleaning surfaces between donation."The blood bank encourages all healthy individuals to donate blood. To be eligible to donate blood, you must be at least 17 years old, weigh at least 114 pounds, and be in general good health. To make an appointment, visit www.sandiegobloodbank.org or call 619-400-8251. 2376

来源：资阳报