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Johnson & Johnson is beginning a huge final-stage study to try to prove if a single-dose COVID-19 vaccine can protect against the virus. It will be one of the world’s largest coronavirus vaccine studies so far, testing in 60,000 volunteers in the U.S., South Africa, Argentina, Brazil, Chile, Colombia, Mexico and Peru. A handful of other vaccines in the U.S. and elsewhere are already in final testing. The two other vaccine candidates in final-phase testing in the U.S. — candidates made by Moderna and Pfizer — were both approved in July. Earlier this month, Dr. Anthony Fauci said those trials should be filled by the end of September, meaning they should be completed by late November or early December.Hopes are high that answers about at least one could come by year’s end, maybe sooner. U.S. health officials insist the race for a vaccine isn’t cutting corners, despite enormous political pressure. 918

KANSAS CITY, Missouri — A handcuffed man in police custody jumped to his death from a bridge on Interstate 435 just south of the Missouri River and the Missouri 210 exit, according to the Kansas City, Missouri Police Department. 246

LA JOLLA, Calif. (KGTV) -- A San Diego couple who met at a Japanese internment camp during World War II, has died this month. The wife succumbed to effects from the coronavirus.To Garrett Yamada, Elizabeth and Joseph were just mom and dad. "My dad loved fish 'n chips and spam, and my mom was into sushi and fine dining," Yamada laughed. But on May 11, Joseph Yamada died after a long battle with dementia. Nine days later, COVID-19 took Elizabeth. They were both 90 years old. "I miss them, but I'm proud of the life they lived," Yamada said. Through struggle and strife, the Yamadas became a prominent San Diego couple. Joseph was a world-renowned landscape architect whose projects included designs for Sea World, UC San Diego, and the Chula Vista Olympic Training Center. Elizabeth was an English teacher who later became a partner at her husband's firm. "They were a wonderful team together," Yamada said.But their love story began behind bars at Poston Japanese Internment Camp in Arizona. Last May, Elizabeth Kikuchi-Yamada shared her story with 10News about her move to the camp as a 12-year-old girl. During her time there, she wrote letters to respected San Diego city librarian, Clara Breed.Breed fought racial injustice by sending books, trinkets, and hope to children locked up in camp. "Clara cared about helping young people know that there was freedom beyond imprisonment. Freedom of the mind to grow. Freedom of the heart to deepen," Elizabeth Yamada said in 2019. It was a story she shared for decades until the virus suddenly took over. "The tragedy with COVID is it separates you physically," her son said. "But her mind was sharp until the very end."The Yamada's were born two days apart in 1930 and died nine days apart in 2020. They were a loving couple, inseparable, both in life and death. "It was God's timing that they go close together," Garrett Yamada said. Unfortunately, the Yamada family says they will not have a service due to COVID-19 restrictions on gatherings. 2006

LA JOLLA, Calif. (KGTV) - A La Jolla restaurant owner was taken into custody Wednesday on 18 counts, including rape.Daniel Dorado was booked into Central Jail in San Diego about 3 p.m. San Diego Police arrested him on suspicion of six crimes, with multiple counts. 272

KANSAS CITY, Mo. - The numbers are in: more Americans will travel this Thanksgiving than the past 12. The travel organization AAA released its annual holiday travel forecast Thursday. It predicts nearly 51 million Americans will travel at least 50 miles to celebrate the holiday. That's a 3 percent increase from last year, and the highest number since 2005. Travelers can expect to pay more for gasoline than years past, but less for airfare. AAA expects 89 percent of travelers to get to their destination by driving. To avoid getting caught in traffic, experts say you should stay off the roads the Tuesday and Wednesday before Thanksgiving, especially in the afternoons. That's when normal workweek commuters and travelers are on the road at the same time. "Plan ahead. Try to make sure you're getting out the door early in the morning, if possible. If you can travel on the holiday, that would be even better for travelers," explained Tamara Johnson with AAA.Travel experts said the high number of travelers is a good indicator people are earning money and feel comfortable spending it. "A strong economy and labor market are generating rising incomes and higher consumer confidence, fueling a strong year for the travel industry, which will continue into the holiday season," said Bill Sutherland, AAA senior vice president of Travel and Publishing, in a press release.These are the top 10 Thanksgiving travel destinations, according to AAA.    1    Orlando, Florida 1535