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GRAND JUNCTION, Colo. – A 5-year-old girl suffered serious injuries after she was attacked by a bear overnight in east Orchard Mesa.The girl had gone outside around 2:30 a.m. early Sunday to investigate noises she thought were being made by her dog, the girl’s mother told Colorado Parks and Wildlife officers.But the girl’s mother heard her daughter screaming and went outside to see a “large black bear” dragging her daughter, CPW officials said. The bear dropped the girl after her mother screamed at it. Their home is in the east Orchard Mesa area, above the Colorado River corridor, officials said.The girl was transported to St. Mary’s Medical Center in Grand Junction with serious injuries, CPW said. Radio traffic from first responders said she had been bitten on her back and near her head.Officers were tracking the bear, along with federal wildlife officials, on Sunday morning. CPW said area residents could expect to see law enforcement officials and hounds in the area, and ask anyone to report bear sightings to officials. 1045

German Chancellor Angela Merkel has announced she will give up leadership of her center-right Christian Democrat Union party after 18 years in the post, German media has reported. Merkel announced during a meeting with officials that she will not seek to run for re-election at the party's convention in December. But she made clear that she wanted to remain as chancellor, a position she has held since 2005, RTL reported, citing party sources.The announcement is a sign of Merkel's weakened power within her own party, and waning popularity in the country.Both parties under Merkel's ruling coalition -- the CDU and the Social Democratic Party (SPD) -- suffered heavy losses in a regional election over the weekend.While the CDU remained the largest party in the election, which was held in the central state of Hesse, results were down 10% from the previous election.This weekend's election is the second blow to Markel's fragile "grand coalition" government. On October 14, the Christian Social Union, or CSU -- the Bavarian sister party to the CDU -- lost its majority in the Bavarian state parliament.The CSU has dominated politics in the state since the end of World War II, ruling for all but three years over the course of nearly seven decades.Speaking on October 15, Merkel admitted that voters had lost trust in the government and that it was her job to "make sure that trust is won back.""I will work on that with as much vigor as I can," she added.Bavaria bore the brunt of the 2015 refugee crisis; at its peak, thousands of asylum seekers were crossing into the state every day. Since then, both Merkel and her CSU allies have been criticized for their management of the influx. 1700

FULLERTON, Calif. (AP) — The Los Angeles Dodgers say Hall of Fame manager Tom Lasorda has been hospitalized in Southern California. The Dodgers said Sunday that their 93-year-old former manager was in intensive care and resting comfortably at a hospital in Orange County. Lasorda lives in Fullerton. He attended the team’s Game 6 victory over the Tampa Bay Rays on Oct. 27 in Texas that clinched the Dodgers’ first World Series title since 1988. Lasorda managed the Dodgers from 1976-96, guiding them to World Series championships in 1981 and '88, as well as four National League pennants and eight division titles. 623

GENEVA — The U.N. health agency says the world’s largest randomized trial of COVID-19 treatments found “conclusive evidence” that remdesivir, a drug used to treat U.S. President Donald Trump when he fell ill, has little or no effect on severe cases. The World Health Organization has announced long-awaited results of its six-month “Solidarity Therapeutics Trial” that endeavored to see if existing drugs might have an effect on the coronavirus. The study, which was not peer-reviewed, found that four treatments tested — remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon — had “ little or no effect on 28-day mortality or the in-hospital course of COVID-19 among hospitalized patients.” Remdesivir was the only drug of the four that had not largely been ruled out as ineffective in fighting COVID-19. 826

Horseshoe crabs are prehistoric creatures that predate the dinosaurs, but pharmaceutical companies depend on them to this day for their unique blue blood.The crabs’ blood is hypersensitive to endotoxins, making it the perfect testing ground to see if a coronavirus vaccine is harmful to people."The fact that we rely so much on these really primitive creatures that predate the dinosaurs," said Barbara Brummer, the state director of The Nature Conservancy in New Jersey.From Massachusetts to South Carolina, the crabs are collected and taken to laboratories. But one of their largest breeding grounds is right in New Jersey, in the Delaware Bay."The concern is the population of horseshoe crabs in the Delaware Bay has been declining over the years," said Brummer. "They are needed for the ecological value they bring for shorebirds.”Shorebirds rely on the crabs' millions of eggs for food.New Jersey fishermen are banned from using the crabs for bait. But pharmaceutical companies remove about a half-million horseshoe crabs from the ocean every year.In the labs, about one-third of a crab's blood is removed for testing. If the crab's blue blood clots up, the medicine is no good.The crabs are then returned to the ocean.However, a study by the Atlantic States Marine Fisheries Commission estimates about 15% of the crabs do not survive."There is an alternative test," Brummer said. "They have created a test that does not involve the bleeding of the crabs. It is a synthetic material."The synthetic test has been approved in Europe but has not yet been approved in the United States.This story was first reported by Christie Duffy at PIX11 in New York, New York. 1674