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INDIANAPOLIS — The U.S. Food and Drug Administration on Monday granted emergency use authorization to Eli Lilly and Company's experimental COVID-19 antibody treatment bamlanivimab.According to a statement from the company, the drug is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test who are at high risk for progressing to severe COVID-19 and/or hospitalization. Lilly said in a statement the drug should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion."This emergency authorization allows us to make bamlanivimab available as a COVID-19 treatment for recently diagnosed, high-risk patients — adding a valuable tool for doctors fighting the now-increasing burden of this global pandemic," David A. Ricks, Lilly's chairman and CEO, said. "The rapid development and availability of bamlanivimab could not have been achieved without the relentless work of our Lilly team, collaboration across the industry and the urgent work being done by the government to ensure appropriate allocation to patients who need it the most."The emergency use authorization is based on data from BLAZE-1, a randomized, double-blind, placebo-controlled Phase 2 study in patients with recently diagnosed mild to moderate COVID-19 in the outpatient setting. Patients treated with the drug showed reduced viral load and rates of symptoms and hospitalization, Lilly said in the statement. Infusion reactions and other allergic hypersensitivity events have been reported, Lilly said. The emergency use authorization includes a warning for hypersensitivity including anaphylaxis and infusion-related reactions.Lilly said the drug is not authorized for use in patients who are hospitalized due to COVID-19 or who require oxygen therapy due to COVID-19 or who require an increase in baseline oxygen flow rate due to COVID-19 in those on chronic oxygen therapy due to underlying non-COVID-19 related comorbidity."The BLAZE-1 data show bamlanivimab, when given early in the disease course, may help patients clear the virus and reduce COVID-related hospitalizations, supporting our belief that neutralizing antibodies can be an important therapeutic option for patients fighting this virus," Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific officer and president of Lilly Research Laboratories, said. "We're proud of the speed with which we have been able to bring patients this therapy specifically designed to treat COVID-19. We thank those who have contributed to this medical advancement, particularly the clinical trial investigators and participants around the country." This article was written by Bob Blake for WRTV. 2906

Atlanta 1979 was the start of a series of murders that terrorized the city for two years. Nearly 30 African Americans, mostly children and some as young as 9, were found murdered around the city. Catherine Leach-Bell's son, 13-year-old Curtis, was one of the victims in a string of murders between 1979 and 1981. “It hurt because we loved our children, and it really hurt,” she says. Atlanta's mayor, Keisha Bottoms, announced investigators are going to examine old evidence, using new technology to see if they can learn more about the murder cases. Many of them remain unsolved. “I want some closure. I want justice. I want to know who killed Curtis,” says his mother. “His case is still sitting on the shelf getting dusty and rusty.” A jury found Wayne Williams guilty for the murder of two adults. After his conviction, police blamed Williams for being responsible for most of the child murders, but he was never officially charged for those crimes. Williams has maintained his innocence, and some question whether he is responsible for all of the murders. Mayor Bottoms' announcement comes just days before Investigation Discovery's three-hour documentary series about the case, which airs tomorrow. “We'd like to think that the buzz around the film may have had something to do with her decision, but most important is the fact these victims who have so long looking to be heard seem to finally have been heard,” says Pamela Deutsch, an executive producer for the show.Investigators admit they don't know what they'll find and if it will change anything, but they say they owe it to the families to try to use new technology to find any possible new leads. 1675

President Donald Trump and First Lady Melania Trump announced Friday they tested positive for COVID-19, and for the second time this week the world’s focus has shifted to Cleveland, where the timeline of the president’s actions included most of Trump’s family members not wearing masks during the presidential debate, even though they were required indoors for audience members, per the protocols established by the Cleveland Clinic.Although the first lady and the president’s children Ivanka, Don Jr., Eric and Tiffany walked into the debate venue wearing a mask, they sat down and watched the debate without them, in spite of rules mandating everyone in the room wear a surgical blue mask, according to media reports from the night of the debate. Julio Cortez/AP Ivanka Trump and other members of the Trump family arrive before the first presidential debate Tuesday, Sept. 29, 2020, at Case Western University and Cleveland Clinic, in Cleveland, Ohio. (AP Photo/Julio Cortez) Based on notes from the pool of journalists with Joe Biden in the debate hall, a Cleveland Clinic doctor in a white lab coat attempted to get some of the president's guests to wear a mask. The doctor started to approach Trump family guests and offered them one in case they didn't have one. Based on the TV pool notes from journalists inside the debate room, "the doctor never approached the family but as she got closer to them, someone shook their head and no one she reminded to put on a mask ended up putting one on."Dr. Jill Biden, Sen. Chris Coons and others in the Democratic section began to look over, press pool notes state. "Trump family members began to ask their guests what had happened. When the doctor, who refused to comment to the press, walked off the floor, a debate hall staffer told her 'That’s all you can do.'"Ivanka posted a photo before the event wearing a mask, which came off during the debate. Let’s go! ???? pic.twitter.com/sDmKI5WXFN— Ivanka Trump (@IvankaTrump) September 30, 2020 The debate was held at the Health Education Campus, a facility established for both Case Western Reserve University and the Cleveland Clinic. The clinic is serving as the health security adviser to the Commission on Presidential Debates, which guides the commission on safety matters for all four 2020 general election debates. The Cleveland Clinic released a statement Friday confirming that masking was one of the requirements in place for the debate, and that the candidates and those traveling with them all tested negative for coronavirus before entering the debate hall.The full statement reads:“As health advisor to the Commission on Presidential Debates and the host site, we had several requirements to maintain a safe environment that align with CDC guidelines- including temperature checks, hand sanitizing, social distancing and masking. Most importantly, everyone permitted inside the debate hall tested negative for COVID-19 prior to entry. Individuals traveling with both candidates, including the candidates themselves, had been tested and tested negative by their respective campaigns. Based on what we know about the virus and the safety measures we had in place, we believe there is low risk of exposure to our guests. Out of an abundance of caution we are reaching out to our guests to address any questions and concerns, as well as offering testing. We will continue to monitor the information being released by the White House.”Trump mocks Biden for wearing a maskDuring the debate, Trump mocked Democratic presidential nominee and former Vice President Joe Biden for wearing a mask."I don't wear masks like him. Every time you see him, he's got a mask," he said Tuesday. "He could be speaking 200 feet away and he shows up with the biggest mask I've ever seen." Pres. Trump mocks Joe Biden on the issue of masks: "I don't wear masks like him. Every time you see him, he's got a mask. He could be speaking 200 feet away and he shows up with the biggest mask I've ever seen." https://t.co/5Bl4Ob3O2t #Debates2020 pic.twitter.com/OA3ffVcrkg— ABC News (@ABC) September 30, 2020 Where Trump traveled before testing positiveOn Tuesday, Trump and Biden faced off for the first time at Cleveland Clinic’s and Case Western Reserve University’s Health Education Campus.Following a rally that Trump cut short on Wednesday, ABC News reported top aides observed the president not feeling his best, as he appeared exhausted and fatigued. Multiple sources told ABC News that some believed his fatigue stemmed from the intensity of his rally schedule while others began to think it could be coronavirus.Hope Hicks, one of the president's closest advisers, was also on Marine One, the president’s helicopter, when it left the White House to fly to Joint Base Andrews on Wednesday. She was seen walking to the helicopter with other top presidential advisers. None of them were wearing masks.On Thursday, Hicks tested positive for the coronavirus. Trump later flew to New Jersey for a fundraiser.On Friday, Trump tweeted shortly before 1 a.m. that he and the first lady tested positive for COVID-19.RELATED: Timeline of Trump’s activities in week coronavirus hit home This story originally reported by Kaylyn Hlavaty on News5Cleveland.com 5312

It’s been more than two weeks since federal workers, like Lila Johnson, have been to work.Johnson says it’s been hard, but she takes it day by day. At the age of 71, Lila works part-time at the Department of Agriculture as a janitor to supplement her retirement income. However, she's been out of work since December, because of the shutdown.“My biggest concern is when are we gonna go back to work. That's number one,” she says. “Number two is how I’m going to continue making ends meet.” For now, she has to rely on friends and family to help pay her bills and groceries. Because she's a contract worker, it's likely she will not get the back pay Congress usually gives to federal workers once a shutdown is over. “When I do go back to work, I’m still gonna be behind,” she explains. “I'm gonna have to work at least two months before I can see myself climbing out of the hole.” Other federal workers wonder what they'll do when they don't get paid this week. “I just bought a house,” says furloughed worker Christine Vitel. “I'm not gonna be able to pay my mortgage, so yes, this is affecting me personally. Other people are married. They do have another income. I do not.”As the shutdown stretches into its third week, federal workers are stretched thin trying to find ways to make ends meet. 1309

Cleveland Indians manager Terry Francona had his two World Series rings stolen in Tucson last month.According to the Pima County Sheriff's Department, on Nov. 7, deputies responded to the 6300 block of North Via Lomas De Paloma where they learned of the theft.PCSD then learned that the rings were sold to a sports memorabilia store in Phoenix.After further investigation, the rings were recovered. 411