临沧女士尿急怎么回事临沧姨妈没来但是肚子疼是怎么回事,临沧女性问题在线咨询,临沧不要孩子哪个妇科医院好,临沧得了阴虱症状,临沧阴道口又痒又痛怎么办,临沧同房出血多久可以再次,临沧治疗一度宫颈糜烂要费用

SAN DIEGO (KGTV) — In some of the most severe cases of COVID-19, doctors are finding it’s not the coronavirus making people critically ill.It’s their own immune system, and a San Diego-based biotech company thinks it has an answer.La Jolla-based INmune Bio announced Tuesday it has FDA approval to begin a Phase 2 clinical trial on its inflammation fighting drug, Quellor.In many of the sickest COVID patients, doctors have noticed their blood is filled with high levels of immune proteins called cytokines. Cytokines act as messengers between cells and the virus can cause them to go haywire, setting off what’s known as a cytokine storm.In a cytokine storm, the body’s immune system starts to attack its own cells and tissues rather than the virus. During the Spanish Flu of 1918, many of the deaths were caused by cytokine storms.“You need to control the cytokine storm to keep patients from getting sick,” said INmune Bio’s CEO Dr. R.J. Tesi.There are several different types of cytokines. A drug undergoing testing in a federal trial with remdesivir targets a cytokine called beta interferon.The San Diego biotech’s drug Quellor suppresses a very specific cytokine called soluble tumor necrosis factor, which Dr. Tesi calls “the master cytokine” because of its role in triggering other immune proteins.Dr. Tesi said this particular cytokine may contribute to another troubling issue with COVID-19: blood clotting.“When they write the history of COVID-19, the clots are going to be the bad guy,” Dr. Tesi said. “These blood clots go off everywhere and they gum up the works. They make it so the lungs can't work. They make it so the kidneys can't work. They make it so the heart is screwed up. Make it so you have strokes.”INmune Bio, which is publicly traded but has just six full-time employees, is hoping its drug can address both the blood clots and the inflammation.The company plans to enroll 366 hospitalized COVID-19 patients for a Phase 2 trial to see if intervention with Quellor can keep people off ventilators and out of the ICU. 2053

SAN DIEGO (KGTV) -- Local gym owners are faced with another difficult decision as San Diego County moves into the purple tier, the most restrictive of the state’s classifications of COVID-19 spread.Under the new regulations, gyms may not operate indoors, meaning those who cannot operate outdoors will be mandated to close.The restrictions take effect Saturday.RELATED: County moves into California's COVID-19 purple tier“You want your members happy. You want your staff happy. You’ve got to put food on your table. And you’re trying to do the right thing, you’re wearing a mask and you’re indoors, so it’s going to be just an unbelievable, worrisome time,” said Bryan Welch, general manager of the Point Loma Sports Club.Welch said the new restrictions will not have a significant impact on his gym because the Point Loma Sports Club had already moved 90% of its operations outside. But he said he empathizes with gyms that do not have usable outdoor space or a cooperative landlord.Even some gym owners that can move outside may not choose to do so. They say limits would force them to operate at an untenable loss, leaving them to choose between operating indoors in violation of public health orders or going out of business. One owner, who did not wish to be identified, told ABC 10News he plans to continue indoor operations in order to stay in business.RELATED: Restrictions to hit retailers as holidays approachWhile Welch is empathetic to gyms facing that tough decision, he said he believes the only way to safely reopen all businesses is for the portion of the public that has eschewed safety measures to commit to wearing masks and social distancing.“I think your freedom actually grows. And you have to wear a piece of cloth on your face. Who cares?” said Welch. 1783

SAN DIEGO (KGTV) - It's one of San Diego's crown jewels. The Hotel Del Coronado has been a landmark of America's Finest City since 1888.While its walls are steeped in history, recently, rumors swirled that a face-changing paint job to the hotel's lobby was coming.Facebook users on the "Coronado Happenings" page voiced worries that the iconic hotel planned to paint its wood-finished lobby white.Do you have a fact or fiction question? Submit your question to 10News here.Those rumors, however, are just that, according to the hotel.Hotel Del Coronado's Public Relations Director Sara Baumann told 10News there were discussions of possible upgrades to retail shops on the hotel's lower level, but nothing regarding painting planned for the lobby. Nothing has been set in stone for any upgrades in any space, as well, Baumann added.Could that change even be made to a National Historic Landmark? According to the National Parks Service, "property owners are free to make whatever changes they wish if Federal funding, licensing, or permits are not involved." 1086

SAN DIEGO (KGTV) — In a statement, the City of San Diego says it wasn't given enough time ahead of the July 4 weekend to close beach parking lots.Friday, California Office of Emergency Services sent a letter to city managers in the county asking them to close their beach parking lots ahead of the weekend. The letter was sent to officials in San Diego, Imperial Beach, Coronado, Del Mar, Solana Beach, Encinitas, Carlsbad, and Oceanside."At the time of writing, beaches under the jurisdiction of local governments within San Diego County are the only beaches without visitation restrictions throughout all of Southern California, and therefore are attracting thousands of residents from outside your coastal communities and creating significant potential for disease transmission, particularly in crowded restaurants, bars, retail, and hotels," the letter stated. "... To protect the public health of San Diegans and reduce the high potential transmission of this deadly disease in San Diego coastal businesses, we write to request that municipal governments do not open beach parking lots for the July 4th holiday weekend."RELATED: Crowds flock to San Diego beaches for Fourth of July weekendOceanside announced it would close beach parking lots on Thursday, while Carlsbad said late Friday that it would do the same. California also said Friday that state beach parking lots would be closed this weekend. Carlsbad said they were closing parking lots in anticipation of people traveling to San Diego for the weekend. Surrounding counties Los Angeles, Orange, Ventura, and Santa Barbara have closed beaches this weekend.City of San Diego Chief Operating Officer Kris Michell said in a statement to City News Service that San Diego wasn't given enough time to put a beach parking closure in place."The city of San Diego is closely following county guidance and working with health officials to encourage adherence to public health regulations," Michell said. "The request to regional coastal cities to close beach parking lots on the Fourth of July came last night just a few hours before the start of the holiday, leaving little time to enact, enforce or notify the public.RELATED: Carlsbad closes beach parking lots for holiday weekend"San Diego continues to require facial coverings and physical distancing at all locations, and this week voluntarily implemented restrictions on bars and restaurants to limit the spread of COVID-19," Michell said. "As we have since the beginning of the pandemic, we will continue to work with county and state health officials to protect public health and safety."Imperial Beach, Coronado, Del Mar, Solana Beach, and Encinitas officials said Saturday their beach parking lots remained open Saturday.Friday, several beaches were already seeing crowds for the holiday weekend. Many people claimed their spots early at Mission Beach and Oceanside.RELATED: Hotels, campgrounds have vacancies over holiday weekendWhile some were able to keep their distance from one another, many did not have on facial coverings when near other people, according to Rich Stropky, Marine Safety Lieutenant for San Diego lifeguards.“The majority of them are not wearing masks, I would say at this point in time,” said Stropky. “As far as the capacity for our beaches, what has limited capacity in the past is the ability to park. How far are people willing to park and still walk to the beach? Are they going to Uber in? Are they going to do drop-offs?”Law enforcement agencies have said they will focus on educations, rather than enforcement, of public health orders this weekend. 3604

SAN DIEGO (KGTV) -- If you've ever gone out in the Gaslamp, you know how busy it can get. Nothing will ruin your night more than finding out your car's been towed.That's exactly what's happened more than 1,000 times since the city converted Fifth Avenue to a three-minute passenger loading zone after 8 p.m. on Friday and Saturday nights in September 2016. "They really don't ask questions around here," said Vanessa Figueroa, who hands out fliers for Gaslamp BBQ on the corner of 5th and Island every Friday and Saturday nights. "If you're parked here, your car's gone."The city made the change to reduce gridlock, boost emergency response times, and make passenger drop-offs safer. But that's also meant a lot of towing. In the first year, the city towed about 1,200 cars - drivers either missing the warning signs or getting confused by different ones next to each other.RELATED:  906