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A team at the University of Kentucky is researching a possible treatment for COVID-19 and key helpers are three alpacas; Big Boy, Blue Eyes and Emperor.“It’s a powerful technology that we have at UK (University of Kentucky) and it’s something that hopefully we can develop some therapeutics with,” said Wally Whiteheart, a professor in the Department of Molecular & Cellular Biochemistry.Alpacas, along with llamas and camels, make a special kind of antibody called a nanobody. Nanobodies can be useful in cancer research and for other diseases. Researchers, led by Whiteheart and fellow professor Lou Hersh, are working with a nearby ranch to see what impact alpacas could have on COVID-19.“We, in a sense vaccinate them, and this case with viral proteins, and we make nanobodies to those viral proteins,” explained Whiteheart. “We can then go and purify and identify the nanobodies that bind to the virus and then test them to see if they can inhibit viral infection.”Making the nanobodies is just the first step. The team will see which, if any, can block virus infection and those candidates could move on to clinical trials.There’s still a lot of research and testing to go, and also still a lot of hope.“The cool thing which we’re exploring now is the fact that you might be able to use them as a nasal spray and this actually gets them to the place where the virus is affecting lung tissue,” said Whiteheart.This isn’t the first time the trio of alpacas has helped medical research. Big Boy, Blue Eyes and Emperor have contributed to the university’s nanobody research for more than three years. In that time, they have helped researchers generate more than 50 nanobodies to target proteins involved in a variety of human diseases including cancer, diabetes and neurological disorders.This story was originally reported by Alex Valverde on LEX18.com. 1869
A new study suggests partisan political rhetoric can influence compliance with emergency orders in natural disaster situations.The study, done by researchers at UCLA, found a level of “hurricane skepticism” among those who voted for President Donald Trump during evacuation warnings for Hurricane Irma in Florida during September 2017. Irma reached a Category 5 status, with sustained winds of 180 mph.Researchers point to a moment when conservative commentator Rush Limbaugh made comments just weeks after Hurricane Harvey hit, and about 12 days before Irma, that hurricane warnings and safety precautions were being blown out of proportion.“[T]here is a desire to advance this climate change agenda, and hurricanes are one of the fastest and best ways to do it,” Limbaugh is quoted in the study, “These storms, once they actually hit, are never as strong as they’re reported.”The research was published this month in Science Advances. It compares evacuation reactions during Hurricane Matthew in 2016, Harvey in August 2017 and Irma in September 2017. They used cell phone data for the geography and movement of people, and precinct voting information to estimate neighborhood political preference.“Likely Trump-voting Florida residents were 10 to 11 percentage points less likely to evacuate Hurricane Irma than Clinton voters (34% versus 45%), a gap not present in prior hurricanes,” the study’s authors wrote.Following Limbaugh’s comments, other conversative commentators, including Ann Coulter echoed the sentiments that the warnings were being made to convince people about climate change and not necessarily an indication of the storm’s size. Limbaugh, the study notes, evacuated his Palm Beach, Florida, home a few days after he made his comments.The researchers found an increase in “media-led suspicion of hurricane forecasts” and a resulting divide in people taking protective measures, illustrates the consequence of “science denialism.” They found Google searches confirmed “both the novelty and virality of this hurricane skepticism, peaking just before Irma made Florida landfall.”The research found similar political differences in evacuation reactions during Irma whether or not there were official government warnings to evacuate.In conclusion, researchers worry about the impact “hurricane skepticism” has on keeping people safe during disasters.“Federal agencies, including the National Oceanic and Atmospheric Administration (NOAA) and the Federal Emergency Management Agency are increasingly investing in efforts to counter hurricane rumors and misinformation, diverting limited resources and personnel from more critical tasks and reporting,” they state.In fact, currently, officials in Oregon have launched efforts to combat rumors about the cause of wildfires in their state. According to USA Today, several Facebook posts have gone viral in recent days that claim the fires were started in connection with ongoing civil unrest in Portland.According to Oregon Live, many of the rumors about Antifa starting wildfires were shared by supporters of QAnon — a baseless conspiracy theory that claims President Donald Trump is battling members of the "Deep State" and a satanic cult of pedophiles and cannibals. Other mainstream conservative pundits also contributed in spreading the rumors.Oregon Live notes that officials are investigating one of the dozens of fires in the state as a potential arson, though there is currently no indication that civil unrest was the motive. 3505
A student was taken into custody Friday after a shooting at a Noblesville, Indiana, middle school left three people injured, officials said.Noblesville police Chief Kevin Jowitt told reporters that a teacher and a student were taken to hospitals with injuries from the shooting at Noblesville West Middle School. But hospital officials said at least three people, including one adult, were being treated. One student had an ankle fracture.Jowitt said the shooting in the city of 60,000, about 25 miles northeast of Indianapolis, was reported shortly after 9 a.m.A student asked for permission to leave the classroom and "he returned armed with two handguns," Jowitt said at an afternoon news conference.The situation was quickly resolved, and the student was arrested in or near the classroom, police public information officer Lt. Bruce Barnes said.Jowitt said a secondary threat was received at Noblesville High School."We have multiple officers and a command post established at Noblesville High School and are diligently ensuring the safety of students and staff there," he said. "We have not received any information that this has been anything other than a communicated threat."Barnes said police are seeking several search warrants in their investigation. Police don't know the motive or where the guns came from, he said.Authorities did not release the name of the suspect or the names and conditions of the injured people. However, the teacher was identified as Jason Seaman, 29, according to his aunt, Brenda Hubly-Sushka.Gov. Eric J. Holcomb, who was returning from a trip to Europe, said in a statement that he was monitoring the situation and that about 100 Indiana State Police officers were made available to work with local authorities."Our thoughts are with all those affected by this horrible situation," his statement said.Vice President Mike Pence tweeted, "Karen and I are praying for the victims of the terrible shooting in Indiana. To everyone in the Noblesville community -- you are on our hearts and in our prayers. Thanks for the swift response by Hoosier law enforcement and first responders."The middle school was on lockdown part of the morning, said Jackie Chatteron, a receptionist for the school district. Aerial news video showed rows of students being evacuated and escorted to school buses. Students were taken to Noblesville High for parents to pick up, state police said.June 1 is the last day of classes, according to the school's website.The shooting comes a week after 10 people were killed at a school in Santa Fe, Texas.There have been 23 school shootings where someone was hurt or killed so far this year -- an average of more than one shooting a week. 2704
A new self-driving shuttle bus got off to a bumpy start in Las Vegas.When the service debuted in the city on Wednesday, one of the driverless vehicles was involved in a collision with a delivery truck, the Las Vegas government said in a statement.During the incident in downtown Las Vegas, the bus automatically stopped to try avoid an accident after its sensors detected the truck, the city said. 405
A suspicious package targeting billionaire investor and philanthropist George Soros was rendered safe in Bedford, New York on Monday, a law enforcement source told CNN.The Bedford Police say they received a call reporting a suspicious package found in a mailbox. The package appeared to be an explosive device, police said.An employee had opened the parcel. The employee placed the package in a wooded area and called the Bedford Police, according to a news release.The package did not detonate on its own, the law enforcement source said. 547