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The U.S. reached another bleak milestone in the COVID-19 pandemic Wednesday, as Johns Hopkins University reports that 150,000 Americans have now died of the virus.By comparison, about 116,000 Americans died in World War I, according to Encyclopedia Britannica All recorded U.S. deaths have come in the span of just under six months.The U.S. continues to lead the world in deaths linked to the coronavirus. Brazil, with a death toll of about 88,000, is currently the only other country with more than 50,000 deaths.The U.S. currently has more than 4.3 million confirmed cases of the virus, also the most among all world nations.In recent days, the U.S. has seen daily confirmed cases drop slightly, following several consecutive days of near-record case increases. The spread of the virus in hotspots like Arizona, Florida and Texas appears to be slowing.However, Dr. Anthony Fauci — the nation's top expert on infectious diseases — says he is concerned that hotspots could begin moving to Midwest states. Cases are beginning to tick up in places like Missouri, Nebraska and Colorado. 1091

The way doctors treat asthma in both children and adults just got a major update.Speaking to the Journal of the American Medical Association, respiratory experts said the changes in guidelines focus on six key areas, including improving asthma diagnosis, management, and treatment.It’s the first published update in 13 years.“So, one of the goals of our update was to address the issue of who can use intermittent inhaled corticosteroids and when used, are they as effective as daily use,” said Michelle M. Cloutier, MD with UConn Health.One of the biggest changes is that many patients may not need to use an inhaler every day anymore.“Especially those families of young children who don’t necessarily buy into using daily medication when their children are having intermittent symptoms,” said Stephanie Lovinsky-Desir, MD, MS with Columbia University Irving Medical Center.The new recommendations for inhaler use vary by age and severity of asthma, so it’s important to talk to your doctor about the new guidelines.Asthma affects nearly 5% of adults and 10% of children.During the pandemic, because of the higher death rate of asthma patients from COVID-19, more people have been seeking treatment for the condition.The average annual cost of asthma per person is more than ,200. But research has also shown among other things, regular use of medication and flu vaccines can reduce the chances of someone with asthma being hospitalized, driving up those costs. 1472

The Senate Intelligence Committee voted 10-5 closed doors Wednesday to advance Gina Haspel's nomination as President Donald Trump's CIA director pick, advancing the nominee to a full floor vote where she looks all but assured to win Senate confirmation.Two of the committee's seven Democrats have said they are supporting Haspel, including Virginia's Sen. Mark Warner, the top Democrat on the panel. Haspel currently has more than enough support to win confirmation, as Warner was one of three Democrats to announce Tuesday that they were voting for her, bringing the total to five.   602

The United States is on pace to see its highest number of overdose deaths ever since record keeping began.Between October 2019 and October 2020, 74,000 overdose deaths were reported in the country, up from 68,000 during the same time period the previous year.In local municipalities, the numbers are even more staggering as many cities already surpassed their 2019 numbers through the first nine months of this year, and experts say the pandemic is only fueling the rise.The Associated Press analyzed preliminary overdose statistics in nine states across the country: Colorado, Kentucky, Texas, Connecticut, Massachusetts, Missouri, Rhode Island, New Jersey, and Washington. All of the states showed marked increased in overdose numbers from 2019 to 2020.In Colorado, for example, overdose deaths increased by 28%. In Denver, specifically, that rise was being fueled by the opiate fentanyl, which has been trafficked more across the U.S. Mexico border during the pandemic due to its strength.According Denver’s Medical Examiner’s Office, fentanyl deaths increased tenfold between 2018 and 2020. In 2019, the city reported 56 overdoses from the drug. Through October of this year, that number has skyrocketed to 108.“Drug overdoses are exceeding every metric that we’ve seen for the last decade,” said Dr. Jim Caruso, who is the coroner for the City and County of Denver. “We have had fentanyl related deaths in individuals as young as nine years old. Kids are always tough and they’ve been tough my whole career because you’re looking at the most lost years of productive life.”Dr. Ken Leonard is the Director of the Research Institute on Addictions at the University of Buffalo and says since the start of the pandemic, overdose deaths have only increased at a faster rate, particularly among those with existing drug issues.According to the AP’s analysis, deaths in all nine states peaked in either April or May, just after the tightest stages of quarantine began.Dr. Leonard says the economic consequences of the pandemic forced many drug treatment centers to either furlough or cut employees to save money, affecting accessibility to treatment. He says the isolation from support networks during quarantine may have also played a role in the rise.“The pandemic and the isolation, for a lot of people the unemployment, it all creates a tremendous amount of stress,” said Leonard.Because it takes months to tabulate national overdose death numbers, the true extent of what is happening may not be known until next year, despite early indicators that we are already in the midst of an unprecedented drug epidemic taking place during this pandemic. 2656

The two women from Hawaii who say they were lost at sea had an emergency beacon on the ship that was not activated during their roughly five months at sea, a Coast Guard spokeswoman tells CNN.The mariners, Jennifer Appel and Tasha Fuiava, had one EPIRB (Emergency Position Indicating Radio Beacon) on board, which was properly registered," Coast Guard Petty Officer 2nd Class Tara Molle told CNN.The emergency beacon, which is found on many vessels, is used to alert rescue locations around the world in the event of an emergency, "by transmitting a coded message on the 406 MHz distress frequency via satellite and earth stations to the nearest rescue coordination center," according to EPIRB.com. 706