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CLEVELAND — Scientists at the Cleveland Clinic Lerner Research Institute have successfully reversed Alzheimer's disease in mice.According to a news release, the researchers reversed the formation of harmful plaque in the mice's brains by gradually reducing an enzyme called BACE1, improving their mental function.“To our knowledge, this is the first observation of such a dramatic reversal of amyloid deposition in any study of Alzheimer’s disease mouse models,” says Riqiang Yan, one of the scientists on the team. The study raises hopes that drugs aimed at this same enzyme will soon be able to treat Alzheimer's disease in humans. You can read the full study in the Journal of Experimental Medicine here. 735

CINCINNATI, Ohio — Customs officials in Cincinnati discovered thousands of live crabs that they said someone was trying to smuggle into the country.Agriculture specialists with U.S. Customs and Border Protection discovered the invasive Chinese mitten crabs on Oct. 16 while conducting routine inspections, the agency said in a news release.The crabs are considered a seasonal delicacy in Asia, according to Customs officials. But they have had a "disastrous impact" on habitats where they've been introduced.The crabs were hidden in packages labeled as various types of clothing. They were being sent to various residences in New York. The shipments were refused entry into the U.S. Across the country, Customs agriculture specialists intercepted more than 352 pests and 4,638 quarantine materials on any given day in the fiscal year 2017, according to the agency. 877

Codeine prescriptions for children who have had their tonsils and adenoids removed have decreased since the Food and Drug Administration began requiring a black box warning on the products four years ago, according to a new report from the American Academy of Pediatrics. However, some children continue to be prescribed codeine, and other opioid prescriptions for children have continued to rise since then.Between 2010 and 2015, doctors collected data on more than 350,000 privately insured children up to 18 years old who had undergone those surgical procedures. They monitored the children's prescriptions for codeine and alternative opioids.Codeine, an opioid pain reliever, came under scrutiny due to its adverse effects on children. According to the FDA, it led to serious breathing troubles, including 24 deaths, in children from January 1969 to May 2015.In August 2012, the FDA launched an investigation into the safety of codeine use in children. Afterward, in 2013, it announced a requirement for a black box warning to be added to packaging to call attention to these risks.RELATED: Opioid-addicted babies have quadrupled in numbers 1152

College students are stepping up to help working moms during the pandemic with a virtual tutoring service called Project Matriarchs.Two students on a gap year came up with the idea. After talking with parents about balancing work and remote learning for their kids, they found moms were shouldering most of the responsibilities. Some were resorting to dropping out of the workforce.“It was just this reoccurring conversation we'd have where people felt so overwhelmed and so alone and we were like OK we just, we need to do something, not only for these women who are experiencing this right now, but also for ourselves in our peer group who are going to be inheriting these norms very soon,” said Lola McAllister, co-founder of Project Matriarchs.Here's how it works. Forms to sign up are online. College students will be vetted to become tutors. Then, the site will match them with kids based on availability and what subject they need help with. The tutors can either volunteer or make an hour, but most parents don't pay anything at all.Project Matriarchs relies on donations to keep the service available for families who need it most.“So many of these kids in different school systems especially are getting left behind, not on purpose or not because the teacher can help it, but just kind of having the one-on-one support that isn't a cost burden that is accessible to everyone I think has just proven to be really important,” said Pilar McDonald, co-founder of Project Matriarchs.The founders are now in talks with employers about offering their service. 1574

CITY HEIGHTS, Calif. (KGTV) - A woman in City Heights said she discovered a power cord connected to her building’s utility box, leading into nearby Swan Canyon.After pulling it up, she said it was connected to a power strip and phone charger. She suspects it was being used by homeless people who live in the canyon.The woman did not want to be identified, saying the transients in the area have been aggressive at defending their campsites. She’s worried about the safety of her and her young children, who often like to walk on the trails.She believes the cord wasn’t there for more than a day, though she claims neighbors have also sighted people using the outlet to charge phones.She said she’s worried less about her electricity bill than the potential for the haphazard wiring to spark fires in the dry open space.Her husband, who works for the property manager, put a new lock on the utility closet though she suspects it won’t last long. It’s been ripped open before.She said they’ve reached out to SDG&E and have reported the issues to the city on the “Get it done” app.  1097