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LA JOLLA (KGTV): Researchers at the UC San Diego Moores Cancer Center and the La Jolla Institute of Allergy and Immunology have teamed up to find a new way to fight cancer.They've created a vaccine that can help teach the immune system how to attack only cancer cells and leave the rest of the body alone."Patients will be able to tolerate their therapy much better than they have so far on conventional approaches," says Dr. Stephen Schoenberger from the La Jolla Institute.Each vaccine is highly personalized to the patient. According to a release from UC San Diego, the vaccines "defines the neoantigens – foreign protein fragments recognized by the immune system – in a patient’s cancer. With neoantigens identified, the team can identify peptides – strings of amino acids – that can be used to create a vaccine to stimulate a protective immune system response."Simply put, the new vaccine takes information from a patient's immune system and the tumor and uses it to help white blood cells to fight it."We're giving them life and giving them hope," says Dr. Schoenberger.The first patient in the clinical trial is Tamara Strauss. She was diagnosed with pancreatic cancer in 2015 and went through chemotherapy and surgery."It was brutal," says Strauss. "It's been three and a half years of hell."Strauss' parents helped fund the clinical trial with a million donation. She says she feels fortunate they could do that, but also hopeful that it helps others down the road."I really pray that this vaccine and personalized form of treatment really does change the paradigm of cancer treatment," says Strauss.During the trial, ten patients will get three doses of the vaccine. They'll also be on Keytruda, an immune system boosting drug for up to two years. Their health will be monitored for five years to determine the vaccine's effectiveness. 1871
JAKARTA, Indonesia (AP) -- The Latest on a tsunami that hit the coast around Indonesia's Sunda Strait (all times local):11:26 a.m. The tsunami death toll rose to 62 with 20 missing, according to a spokesperson for Indonesia's disaster agency.8:35 a.m. Indonesia's disaster management agency says the death toll from a tsunami apparently caused by undersea landslides from a volcanic eruption has risen to 43 with some 600 injured. Scientists say the tsunami could have been caused by the eruption of Anak Krakatau, a volcanic island formed over years from the nearby Krakatau volcano. They also cited tidal waves caused by the full moon.The areas that were affected were South Lampung in Sumatra and the Serang and Pandeglang regions of Java, west of the capital Jakarta. The Sunda Strait between the islands of Java and Sumatra connects the Java Sea to the Indian Ocean.7:05 a.m.A man who says he and his family survived the tsunami that hit the coast around Indonesia's Sunda Strait says he was taking pictures of a volcano Saturday night when he suddenly saw a big wave come toward him. "I had to run, as the wave passed the beach and landed 15-20m (meters) inland," ╪ystein Lund Andersen writes on Facebook. "Next wave entered the hotel area where i was staying and downed cars on the road behind it. Managed to evacuate with my family to higher ground trough forest paths and villages, where we are taken care of (by) the locals. Were unharmed, thankfully." 7:05 a.m.Anderson writes that authorities are saying it appears to be a tsunami caused by a volcanic eruption that he was photographing. "So encountered my first tsunami it seems, hopefully my last," Anderson writes. 6:45 a.m.Government officials say that at least 20 people were killed after a tsunami hit the coast around Indonesia's Sunda Strait, the BBC reports.The national disaster management agency says 165 people were hurt and dozens of buildings were damaged Saturday night, according to the BBC.The agency says the possible cause of the tsunami were undersea landslides after the Krakatoa volcano erupted.The Sunda Strait between the islands of Java and Sumatra connects the Java Sea to the Indian Ocean.The BBC reports that footage posted by the head of the disaster management agency showed the aftermath of the tsunami, with flooded streets and an overturned car.In September, at least 832 people were killed by a quake and tsunami that hit the city of Palu on the island of Sulawesi, which is just east of Borneo. 2499
KANSAS CITY, Mo. — An attorney has filed a lawsuit against Ripley Entertainment, Inc. on behalf of some members of the Indianapolis, Indiana family killed in a duck boat incident in Branson, Missouri.The Ride the Ducks Branson vehicle capsized and sank on July 19, amid strong storm winds and taking on too much water. Seventeen people died, including the driver of the boat and nine members of a family of 11 on vacation from Indianapolis. The victims’ ages ranged from just 1 year old, to 76 years old.The lawsuit alleges wrongful death, outrageous conduct and negligence in the incident, and seeks at least 0 million in damages.Attorney Gregory W. Alshire is representing John D. Coleman, the administrator of estate for Ervin Coleman, killed in the incident, along with Lisa D. Berry and Marlo Rose Wells, who are the administrators of estate for victim Maxwell Ly. 895
KALAMAZOO, Michigan (AP) — The first trucks carrying a COVID-19 vaccine for widespread use in the United States have pulled out of a Michigan manufacturing plant. The shipments Sunday morning set in motion the biggest vaccination effort in American history. The shots that are critical to stopping the nation’s coronavirus outbreak are destined to reach states a day later. Initial doses of the Pfizer vaccine will likely be limited to health workers and nursing home residents. The Food and Drug Administration authorized emergency use of the vaccine Friday, saying it is highly protective and presents no major safety issues. 635
KANSAS CITY, Mo. — Missouri Gov. Mike Parson launched into an impassioned and unprompted defense of the St. Louis couple seen waving guns at Black Lives Matter protesters last month and later suggested that President Donald Trump has taken an interest in the situation.Mark and Patricia McCloskey were seen on video June 28, brandishing an AR-15 rifle and a handgun while confronting protesters marching through the Portland Place neighborhood, where the McCloskeys live.Police in St. Louis executed a search warrant at the McCloskey home Friday at the behest of St. Louis City Circuit Attorney Kim Gardner’s office. The couple’s lawyer said police seized an AR-15 from the house and that the couple had previously surrendered the handgun.On Tuesday, after introducing a new grant program for small businesses during a press conference, Parson told reporters that he wanted “to address the McCloskey situation in St. Louis.”Parson said the McCloskeys were using the Castle Doctrine to protect their property from protesters, “which they had every right to do.”During his time as a state legislator, Parson helped expand the Castle Doctrine in Missouri — a stand-your-ground law that permits property owners to use any means deemed necessary, including deadly force, to protect themselves and their property when threatened.Parson said police weren’t notified of the situation before reiterating “that couple had every right to protect their property."He then slammed the District Attorney's office, without directly naming Gardner, for reportedly considering an indictment in the case.“What they should not go through is a prosecutor attempting to take their constitutional rights away by filing charges against them for protecting their property,” Parson said.He then said it was very difficult to remove an elected official — like Gardner — from office, calling it “one of the things we need to address in future sessions.”It was at that point Parson invoked the White House.“I just got off the phone with the president of the United States before I walked out here today,” Parson said. “He understands the situation in Missouri. He understands the situation in St. Louis — and how out of control it is for a prosecutor to let violent criminals off and not do their job and try to attack law-abiding citizens.”Parson said Trump promised to do “everything he could within his powers to help with this situation and that he would be taking action to do that.”“I’m thankful that he’s getting involved in the situation,” Parson said "... I’m thankful that he’s going to stand up for people and their legal rights.”After opening up to questions, Parson acknowledged that “all I know is what I’ve heard” about the McCloskey case and that “I don’t know all the details of it,” but that “it’s quite evident they are standing on their property.”“I think the president and the attorney general of the United States (William Barr) are going to take a look at it,” Parson said.He later added, “The president doesn’t like what he’s seeing and the way these people are being treated. I know the attorney general was represented on that phone call today, so I think you’ll see some sort of actions. I think they’re going to look into things.”Parson plans to have follow-up conversations with Trump after expressing his concern over the limited power the Missouri governor has to remove other elected officials, among other things.“I don’t want to make it sound like he’s going to come in here and remove somebody from office, but I’m going to guarantee you the president’s focused on what’s happening here,” Parson said.Parson has a press conference planned for Wednesday when he is likely to announce details of a special session about violent crime in Missouri.The governor declined to discuss specifics of the special session. Democratic lawmakers have been calling for a special session on police reform since George Floyd’s death in late May sparked protests nationwide about policing and racism.“My biggest concern right now for the state of Missouri is violent crime, homicides,” Parson said. “... We have to give the law enforcement officers the tools they need to fight violent crime. And, right now, more important than anything, we’ve got to stand up for these law enforcement officers that are dealing with violent crime.”He blamed the protests for detracting from an officers’ ability to focus on “the street crimes that are happening out there and these violent crime situations.”This story was originally published by Tod Palmer on KSHB in Kansas City, Missouri. 4572