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NEW YORK (AP) — U.S. health officials have sparked a wave of confusion after posting guidelines that coronavirus testing is not necessary for people who have been in close contact with infected people. The new guidance was posted earlier this week on the website of the Centers for Disease Control and Prevention. The agency formerly advised testing for close contacts. But on Monday that was changed to say that testing is no longer recommended for symptom-less people who were within 6 feet of an infected person for more than 15 minutes. CDC officials have referred all questions to the agency’s parent organization, the U.S. Department of Health and Human Services in Washington. 691
New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccine.“Infection with this coronavirus does not necessarily generate lifetime immunity,” but antibodies are only part of the story, said Dr. Buddy Creech, an infectious disease specialist at Vanderbilt University. He had no role in the work, published Tuesday in the New England Journal of Medicine.The immune system remembers how to make fresh antibodies if needed and other parts of it also can mount an attack, he said.Antibodies are proteins that white blood cells called B cells make to bind to the virus and help eliminate it. The earliest ones are fairly crude but as infection goes on, the immune system becomes trained to focus its attack and to make more precise antibodies.Dr. Otto Yang and others at the University of California, Los Angeles, measured these more precise antibodies in 30 patients diagnosed with COVID-19 and four housemates presumed to have the disease. Their average age was 43 and most had mild symptoms.Researchers found that the antibodies had a half-life of 73 days, which means that half of them would be gone after that much time. It dovetails with a previous report from China also suggesting antibodies quickly fade.The results “call for caution regarding antibody-based ‘immunity passports,’ herd immunity, and perhaps vaccine durability,” the California authors write.That’s true, Creech said, but other parts of the immune system also help confer protection. Besides churning out antibodies, B cells develop a memory so they know how to do that again if needed.“They would get called into action very quickly when there’s a new exposure to the virus. It’s as if they lie dormant, just waiting,” he said.Other white blood cells called T cells also are better able to attack the virus the next time they see it, Creech said.Although circulating antibodies may not last long, what we need to know is if and how people remake antibodies if exposed to the coronavirus again and if they protect against another infection, Alison Criss, an immunologist at the University of Virginia, wrote in an email. “We also need to know if there is a protective T cell response” that reappears.Vaccines, which provoke the immune system to make antibodies, might give longer-lasting protection than natural infection because they use purified versions of what stimulates that response, she noted.Creech agreed.“This shouldn’t dissuade us from pursuing a vaccine,” he said. “Antibodies are only a part of the story.”___Marilynn Marchione can be followed on Twitter at http://twitter.com/MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2967
NEW YORK — Each year, twin towers of light shine into the night sky over Manhattan in honor of the thousands killed during the terrorist attack on Sept. 11, but the sky will be a little darker this year.The 'Tribute in Light' was canceled because of concerns over the coronavirus pandemic, 9/11 Memorial and Museum spokesman Michael Frazier said. The annual reading of the names was also recently canceled.“The world’s beloved twin beams of light regrettably will not shine over lower Manhattan as part of this year's tributes to commemorate 9/11," Frazier said. "This incredibly difficult decision was reached in consultation with our partners after concluding the health risks during the pandemic were far too great for the large crew required to produce the annual Tribute in Light."Nearly 40 people usually work in close proximity for several weeks to produce the 'Tribute in Light' each year.The 9/11 Memorial and Museum will parter with NYC & Company and buildings throughout the city to light up their facades and spires in blue in commemoration of the 19th anniversary of 9/11."In a spirit of unity and remembrance, the city will come together for a 'Tribute in Lights' to inspire the world and honor the promise to never forget," Frazier said.Nearly 3,000 people were killed on Sept. 11, 2001 when hijacked planes slammed into the World Trade Center.This article was written by Aliza Chasan for WPIX.The Associated Press contributed to this report. 1469
NEW YORK, N.Y. – Barnes & Noble has warned its customers of a cybersecurity attack which may have exposed consumer information.The bookstore chain informed its customers of the attack in an email Wednesday night, but said their payment information and other financial data has not been compromised, because it’s encrypted and not accessible.However, the email obtained by CNN and Business Insider says the attack resulted in unauthorized access to company systems that do contain customers’ email addresses, billing and shipping addresses, and telephone numbers.The company says it doesn’t currently have evidence that this data has been exposed, but it cannot be ruled out at this stage in the investigation.The company says it learned of the attack on Saturday, Oct. 10.“We take the security of our IT systems extremely seriously and regret sincerely that this incident has occurred,” wrote Barnes & Noble. “We know also that it is concerning and inconvenient to receive notices such as this. We greatly appreciate your understanding and thank you for being a Barnes & Noble customer.”The news of the cyber-attack comes one day after the business experienced a “systems failure” that caused an outage to NOOK content.A spokesperson for the company told Business Insider that the attack was linked to the problems with NOOK and issues processing orders at its stores. 1388
NEW YORK — A wealthy benefactor of the disgraced leader of an upstate New York self-improvement group has been sentenced to more than six years in prison in connection with a federal sex slave case.Seagram’s liquor fortune heiress Clare Bronfman appeared in federal court Wednesday in Brooklyn, where a judge handed her an 81-month prison sentence. She was immediately taken into custody to begin her sentence. Bronfman's lawyers wanted her to get only three years of probation, but prosecutors said she deserves five years behind bars for her support of Keith Raniere.Raniere was convicted of charges last year accusing him of turning some of his followers into sex slaves branded with his initials.Raniere is known as the leader of the group NXIVM. Prosecutors say the organization operated like a cult, in which members formed a secret sorority comprised of brainwashed female “slaves” who were forced to have sex with Raniere.Long affiliated with NXIVM, Bronfman reportedly provided millions of dollars to bankroll Raniere and his program of self-improvement classes and paid for lawyers to defend the group against a lawsuit filed by critics.Last year, Bronfman admitted in a guilty plea that she harbored someone who was living in the U.S. illegally for “labor and services.” She also claimed to have committed credit card fraud on behalf of Raniere.Bronfman’s lawyers argued that she deserved leniency because she didn’t have direct involvement with the most disturbing allegations in the case, but prosecutors said she deserved severe punishment because Raniere likely couldn’t have gotten away with what he did without her. 1640