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SAN DIEGO (KGTV) -- A San Diego native made history at the Ironman World Championships in Hawaii, becoming the first above-the-knee double amputee to finish what many consider the world's most grueling endurance race. Roderick Sewell crossed the finish line of the 140-mile triathlon race in 16 hours and 26 minutes and immediately embraced his mother. The two lived in San Diego homeless shelters when Sewell was growing up."It's amazing to see how far we've come in 20 years," said the 27-year-old.It's even more amazing when you consider that Sewell had never completed a marathon before Saturday's competition. The Ironman triathlon consists of a 2.4-mile swim, a 114-mile bike ride, and ends with a 26.2-mile marathon.On top of that, Sewell had only six months to train after receiving an invitation from the Ironman organization."I had no bike. I didn't own one" until a few months before the competition, said Sewell. Sewell raced with strategy help from his longtime friend and mentor Rudy Garcia-Tolson. Garcia-Tolson became the first above-the-knee double amputee to finish any Ironman 10 years ago."Back when I first met Roderick, he was about 8 years old. He was actually petrified of the water," Garcia-Tolson said. "Whatever life is throwing at you, mental or physical challenges, you have to fight and get over those and strive for better."Sewell, whose legs were amputated at 2 years old because he was born without tibias, credits much of his success to the San Diego-based Challenged Athletes Foundation. He was introduced to the group at 8 years old."I didn't do any kind of sports. I wasn't very physically active," he said. "And then I started with them and got started in every sport I could."CAF gave Sewell his first running blades at a time when he and his mother were living in homeless shelters."If I can inspire someone, it's a blessing," he said. "When people come up to me and tell me their stories, to me their stories seem more mind-blowing than my own," Sewell added. 2009
SAN DIEGO (KGTV) — A small San Diego biotech is trying to give face masks an added layer of defense by spraying the liner with a biological bait designed to be a mousetrap for the coronavirus.AXIM Biotechnologies is also developing a next-generation rapid antibody test that the company says is the first of its kind to detect “neutralizing antibodies.” The neutralizing antibody test should be available for sale in the next few weeks, said CEO John Huemoeller.Both the test and the surgical mask are based on the same technology: a synthetic protein AXIM created that mimics ACE2.ACE2 is a receptor protein found in your body on the surface of cells. The coronavirus likes to bind to it to infiltrate cells, so the company decided to coat the inner lining of a surgical mask with the protein as an added barrier.“They lock to each other just like they do in your body. They lock on the mask. So when we spray the mask with that virus-binding protein, it's there permanently. It can be washed. It's not coming off,” Huemoeller said.“That's the whole idea is to get [the virus] to bind to something, so it cannot go into your respiratory system,” he added.AXIM’s mask is still a ways off from hitting the market. Huemoeller said it needs to undergo further testing to get FDA approval and the company is still looking for a manufacturing partner. The company is hoping to release the enhanced mask by the middle of next year.“We’re hoping that maybe [the FDA will] steamline it because this is something that can save lives,” Huemoeller said.With fewer than 10 scientists, AXIM is a small biotech based in Sorrento Valley. But the company thinks it's poised to be at the center of the second wave of antibody tests for so-called neutralizing antibodies.“When the FDA got our application they didn't know what neutralizing antibodies were. And now everybody's talking about neutralizing antibodies,” said Huemoeller.Not all antibodies function the same. Some antibodies bind to the virus but still allow the pathogen to infiltrate cells. Other antibodies, called neutralizing antibodies, bind to the virus and actually prevent further infection.AXIM’s lateral flow assay antibody test, dubbed Tru-19, takes a drop of blood and can return results in 10 minutes to determine if someone has neutralizing antibodies, according to Huemoeller.In addition to uses at doctors’ offices, the company said the test would have immediate applications at labs processing convalescent plasma.Since as many as one-third of people who recover from COVID-19 do not produce neutralizing antibodies, Huemoeller said the test could help determine which patients would be optimal candidates to donate plasma. 2693

SAN DIEGO (KGTV) - A small coffee shop in Carmel Mountain Ranch is now the world's best coffee roaster.Mostra Coffee just won Roast Magazine's top honor as the 2020 Roaster of the Year."It was a really far fetched, big dream of ours to one day achieve one day," said Mostra Coffee co-founder Jelynn Malone. "So the fact we were able to achieve it in six years is mind-blowing to us."Malone started the company with a few friends in a garage in 4S Ranch. They were looking for ways to help poor people in the Philippines and learned that buying coffee from local farmers can help provide money and jobs to the region."It was rooted in good and wanting to help," said Malone. "We just believed in our mission so much that we thought, you know, let's just go for it. What it's become now is just surreal and amazing."Right now, Mostra Coffee has one shop in Carmel Mountain Ranch, but they have plans to expand. They're opening a second location in 4S Ranch in March and just signed a lease for a spot in Mira Mesa.Malone said their passion for coffee is what's fueled their success."It's very similar to wine," she said. "It'll taste anywhere from peaches to chocolates, to tea leaf flavor notes to blueberry. There are so many different flavor notes you can get out of coffee that I don't think people realize, and you get to do that in specialty coffee."In addition to the new locations, Mostra is expanding into the instant coffee business. They just launched a line of single-serve instant coffee packs."Now you can enjoy Mostra coffee when you're flying or camping or at work or rushing in the morning and don't have time to come into the store," said Malone.Through all the expansion, Malone said they plan to keep the small-batch mentality that brought them this far."The community's been so supportive that I think people will really appreciate having more access to Mostra." 1889
SAN DIEGO (KGTV) - A team led by Scripps Research has yielded positive results in a new research study involving antibodies.Researchers say they've worked to isolate the most potent antibodies in the blood of recovered COVID-19 patients. The study was published in "Science."Dennis Burton, the study's co-author, says once they identified the most potent antibodies, they cloned them."You clone the really good ones, and then you make lots and lots of them in production facilities and then use as a standard to protect and-or treat Covid-19," Burton said.They've tested the cloned antibodies, or monoclonal antibodies, on animals, and they've yielded positive results. They hope to conduct human testing early next year.When asked if it is similar to antibody treatments from convalescent plasma donations, Burton says what they're making is more efficient and can be produced for masses.He says the monoclonal antibodies could be used as a preventive measure given to uninfected but at-risk people before a vaccine is available, and could even be useful for people that may not respond well to a vaccine.He also says the monoclonal antibodies could be used to design better vaccines by giving researchers a better idea of which antibodies are most effective. 1268
SAN DIEGO (KGTV) - A three-day conference is underway at the University of San Diego and its partner schools around the county.It's the 7th Annual Conference on Civility & Civic Dialogue. Moderators and local journalists are discussing the serious threat fake news and deliberate disinformation poses on the country's democracy."Journalism is called the fourth estate of American democracy, without a free press and a believed and trusted press our democracy simply is not going to survive," said conference moderator and political science professor, Dr. Carl Luna.Public trust of the media has hit historic lows in recent years and panelists discussed ways organizations can earn back the public's trust. The San Diego Public Library system offers the public media literacy courses, offering tools to recognize the difference between real news and "fake" news.The Society of Professional Journalists also offers online tools for public use. 958
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