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The first participant in a clinical trial for a vaccine to protect against the new coronavirus will receive an experimental dose on Monday, according to a government official.The National Institutes of Health is funding the trial, which is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle. The official who disclosed plans for the first participant spoke on condition of anonymity because the move has not been publicly announced.Public health officials say it will take a year to 18 months to fully validate any potential vaccine. Testing will begin with 45 young, healthy volunteers with different doses of shots co-developed by NIH and Moderna Inc. There’s no chance participants could get infected from the shots, because they don’t contain the virus itself. The goal is purely to check that the vaccines show no worrisome side effects, setting the stage for larger tests.Dozens of research groups around the world are racing to create a vaccine as COVID-19 cases continue to grow. Importantly, they’re pursuing different types of vaccines — shots developed from new technologies that not only are faster to produce than traditional inoculations but might prove more potent. Some researchers even aim for temporary vaccines, such as shots that might guard people’s health a month or two at a time while longer-lasting protection is developed.Also in the works: Inovio Pharmaceuticals aims to begin safety tests of its vaccine candidate next month in a few dozen volunteers at the University of Pennsylvania and a testing center in Kansas City, Missouri, followed by a similar study in China and South Korea.Even if initial safety tests go well, “you’re talking about a year to a year and a half” before any vaccine could be ready for widespread use, according to Dr. Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases.That still would be a record-setting pace. But manufacturers know the wait — required because it takes additional studies of thousands of people to tell if a vaccine truly protects and does no harm — is hard for a frightened public.President Donald Trump has been pushing for swift action on a vaccine, saying in recent days that the work is “moving along very quickly” and he hopes to see a vaccine “relatively soon.”Today, there are no proven treatments. In China, scientists have been testing a combination of HIV drugs against the new coronavirus, as well as an experimental drug named remdesivir that was in development to fight Ebola. In the U.S., the University of Nebraska Medical Center also began testing remdesivir in some Americans who were found to have COVID-19 after being evacuated from a cruise ship in Japan.For most people, the new coronavirus causes only mild or moderate symptoms, such as fever and cough. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia. The worldwide outbreak has sickened more than 156,000 people and left more than 5,800 dead. The death toll in the United States is more than 50, while infections neared 3,000 across 49 states and the District of Columbia. The vast majority of people recover. According to the World Health Organization, people with mild illness recover in about two weeks, while those with more severe illness may take three weeks to six weeks to recover.___The Associated Press receives support for health and science coverage from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3597
That scene from “Friends” when we find out Ross is still a patient at his pediatrician’s office is getting more common for young adults.One reason is young adults can stay on a parent's insurance until they are 26 years old so it's easier and more affordable to stick with the same doctor.There are downsides though.“If they start to get medical conditions, high blood pressure, hypertension, adult onset diabetes, those more … adult medical conditions, that’s an appropriate time to say, ‘hey maybe it’s time to transition to an adult provider,’ ” said Dr. Christina Johns with PM Pediatrics. The pediatric emergency physician says one benefit of staying on with a pediatrician longer is the patient continues to see someone familiar with their medical history, especially for those with chronic childhood health issues. And she says it prevents the young adults from moving into another trend she's noticing — relying solely on emergency room and urgent care only.“There really does seem to be a large group of adults who use those places as their primary care,” the pediatrician said. “It’s really important to have a relationship with a primary care doctor.”Johns says when young adults become parents and when women need regular OB/GYN care, those are also appropriate times to transition away from a pediatrician.The American Academy of Pediatrics discourages transitioning away from pediatric care solely based on age. Their position is that it’s a decision between a patient and their doctor. It should take into account meeting the needs of the patient and the abilities of the doctor. 1606
Tens of thousands of people were without power in Manhattan on Saturday evening, ConEdison said.There were 42,000 customers without power in New York, most of them in Midtown Manhattan and the Upper West Side, the utility company said.Mayor Bill de Blasio, who was campaigning for president in Iowa, said it appears the outage was the result of a mechanical problem in the electrical grid."This appears to be something that just went wrong in the way that they transmit power from one part of the city to another," he told CNN. "It sounds like it is addressable in a reasonable amount of time."The city's fire department was responding to numerous transformer fires, the first of which occurred in Manhattan on West 64th Street and West End Avenue, officials said.Several Broadway and off-Broadway shows said they were canceling performances, according to tweets aggregated by 889
The National Hurricane Center said late on Wednesday that a disturbance in the northern Gulf of Mexico is nearing tropical depression status. The storm, which will likely become tropical storm Barry on Thursday, has become better organized. Even as just a tropical disturbance, the storm system has already caused massive flooding in the New Orleans area. Parts of the area had nearly 9 inches of rain on Wednesday, with more to come through Saturday. The latest projections take the storm to the Louisiana coast as a hurricane. Latest forecast models put the storm on the coast sometime Saturday. The forecast cone still keeps open the possibility the storm slides to the west, giving the Upper Texas Coast a direct hit.The hurricane watch goes from the Mouth of the Mississippi River westward to Cameron Louisiana.As of 10 p.m. CT, the storm is 240 miles southeast of Morgan City, Louisiana. 906
The controversy surrounding a nurse woman who ran in the London Marathon and was denied the "fastest nurse" world record because she wasn't wearing a dress has sparked a conversation about how the image of nurses has changed.Although not all nurses arrive to work donning white dresses, the stereotypical image of nurses remains.The Guinness World Records admitted that its guidelines were "outdated, incorrect and reflected a stereotype we do not in any way wish to perpetuate," according to Guinness World Records senior vice president Samantha Fay.Mary Lou Creech has been a registered nurse for the last 50 years, and her uniform used to be what you would expect for a stereotypical nurse. A lot has changed over the past decades, especially with her uniform.“I wore the white dress the white shoes the white hat,” Creech remembers. “In ICU that was a nightmare. But that's the way it was, and you just worked around it.”Now, at Vascular Institute of the Rockies, she works in scrubs, which is why she was surprised to learn a nurse was denied a spot with Guinness World Records as fastest marathon runner wearing a nurse's uniform because she wasn't wearing a dress.“That's too bad,” Creech says. “I mean it should be the job that they did, not what they're wearing.”“We were excited to see that social movement and see this new outcome,” says Liz Stokes with the American Nurses Association.Stokes says the image of nursing has changed, and not just in attire.“It's more diverse than the traditional what we saw years ago,” Stokes says. “You know we're more racially and ethnically diverse. Gender diversity as well as age.”She says this conversation can help to shatter stereotypes, but there is still more work to be done.“Our goal is to hope that we reflect what our patient’s population appears to be and we're not there,” Stokes says. “So, we still have a significant way to go.” 1902