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Johnson & Johnson announced it has paused its coronavirus vaccine trials on Monday following an “unexplained illness” among one of its participants.Johnson & Johnson stressed that adverse events during trials are expected, and a pause gives researchers an opportunity to review all of the medical information before moving forward with the trial. Johnson & Johnson added that it’s not always immediately known if the affected person received a placebo or a study treatment.Among the trials paused was Johnson & Johnson’s multi-country “ENSEMBLE” vaccine, which entered Phase 3 testing in September. Johnson & Johnson said last month that its goal was to seek an emergency use authorization approval in early 2021.The FDA noted that a vaccine candidate must be at least 50% effective to receive emergency use authorization. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.” 1554
Judge Amy Coney Barrett described during her confirmation hearing Tuesday the "personal" and "difficult" conversations her family was forced to have following the death of George Floyd in Minneapolis earlier this year.Barrett is the mother of nine children. Two of those children are adopted and are Black."As you can imagine, given that I have two Black children, that was very, very, personal to me and my family," Barrett said.Barrett said her husband and her sons were off on a camping trip when a video went viral that showed Minneapolis Police Officer Derek Chauvin kneeling on Floyd's neck for more than eight minutes prior to Floyd's death. She described watching the video with her adopted daughter, Vivian."For her to understand that there might be a risk to her brother, or a son she might have one day of that kind of brutality has been an ongoing conversation," Barrett said. "And a difficult one like it has been happening for Americans all over the country."Barrett added that it was especially difficult for some of her younger children to grasp."My children, to this point in their lives, have had the benefit of growing up in a cocoon where they have not yet experienced hatred or violence," she said.Sen. Dick Durbin, D-Illinois, then asked if she felt that if she believes overt or systemic racism existed in America."I think it is an entirely uncontroversial and obvious statement given, as we just talked about, the George Floyd video, that racism exists in our country," Barrett said.However, she stopped short of calling racism in America "systemic," saying that in her role as a judge that she was unable to do so."As to the nature of putting my finger on the problem...or how to tackle the issue of making it better, those things are policy questions," Barrett said. "They're hotly contested policy questions that have been in the news and discussed all summer. As I did share my personal experience — and I'm happy to discuss the reaction our family had to the George Floyd video — giving broader statements or making broader diagnoses is beyond what I'm capable of doing as a judge." 2119

JAMUL (CNS) - A woman was killed in Jamul late Friday by a hit-and-run driver who officers were ultimately able to track down and arrest, the California Highway Patrol said Saturday.Around 7:20 p.m. Friday, a 65-year-old woman was crossing Route 94 near Rancho Miguel Road when she was struck by a white Toyota Corolla heading west on the highway, CHP officers said.The Corolla driver at first pulled over and got out of the car, then hopped back in and fled the area, continuing west on Route 94, officials said.The victim was taken by ambulance to a hospital, where she succumbed to her injuries, according to the CHP.Neither the driver nor the victim were publicly named.MAP: Track crime happening in your neighborhoodInvestigators were looking for possible witnesses, and asked anyone who saw the crash to call the California Highway Patrol El Cajon office at (619) 401-2000. 887
LA JOLLA, Calif. (CNS) - Thousands of University of California service workers are expected to begin a three-day strike Monday at campuses and medical facilities across the state, including at UC San Diego's Jacobs Medical Center in La Jolla.Service workers represented by Local 3299 of the American Federation of State, County and Municipal Employees voted overwhelmingly last month to authorize a strike if no progress were made in negotiations.UC officials have repeatedly criticized the union for calling the strike, accusing it of rejecting an offer of "fair, multi-year wage increases and excellent medical and retirement benefits."In light of the impasse, the university system last month imposed contract terms on the union for the 2017-18 fiscal year, including 2 percent pay increases. The UC's latest contract offer to the union included annual 3 percent raises over the next four years, according to the university.The union denounced the move to impose contract terms, responding by issuing a notice of a strike set to last until Wednesday."We've bargained in good faith for over a year to address the widening income, racial and gender disparities that front-line, low-wage workers at UC are living every day," AFSCME Local 3299 President Kathryn Lybarger said. "Instead of joining us in the effort to arrest these trends, UC has insisted on deepening them -- leaving workers no option but to strike."UC officials said in a statement that they "strongly disagree with AFSCME's decision to strike, which will negatively impact patients, students and the UC community.""We are doing everything in our power to limit disruptions on our campuses and medical centers to ensure our patients get the care they need and our students the services they deserve," according to the UC.The UC insisted that its service workers -- including custodians, gardeners, food service workers and facilities maintenance staff -- are compensated at or above the market rate, "and in some cases, by as much as 17 percent higher than comparable jobs."The university Monday said it currently pays workers anywhere between just over ,000 for food service to more than 1,000 for a respiratory therapist.University officials said the union is demanding a 6 percent annual wage increase, "which is twice what other UC employees have received."They said their final offer included, in addition to the pay raises, a lump-sum payment upon contract ratification, health benefits consistent with those of other workers and continuation of pension benefits for existing employees. New employees would be given a choice between a pension or a 401(K)-style retirement plan.Lybarger, however, accused the university of "subverting" the bargaining process by imposing contract terms on workers. 2787
Kate Hudson closed out her week with a big reveal: She's pregnant.The "Marshall" actress announced on Instagram on Friday that she's expecting a baby girl with musician boyfriend Danny Fujikawa. The entire family, she said, is "crazy excited."But, she said, it hasn't been an easy first trimester. 311
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