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SAN DIEGO (KGTV) - As re-closures loom in San Diego County, anxiety is building.Licensed Psychologist Dr. Michelle Carcel said she and other colleagues noticed higher anxiety and depression among those who are isolating."Then there's the reality of, 'okay the cases are surging and things are starting to shut down again,' so there is that isolation anxiety," Dr. Carcel said, explaining we are pack animals and can feel in danger if alone for extended periods of time.She said on the flip side, some are feeling a sense of comfort in a new routine that's taking root, as we enter the fourth month of the pandemic.The possibility of all indoor activities getting shut down Monday threatens that new normal many have created.Dr. Carcel said there are still options to get together, "we can get creative with this. There's hiking outdoors, there's biking we can do. All of that within the context of social distancing." Another anxiety is the job market. While unemployment is down for the sixth straight week, SANDAG said 200,000 San Diegans are still out of work.Dr. Carcel acknowledges these times are hard but it is important to have hope. "We're just constantly thinking in absolutes, 'Oh it will never reopen. It will never get better,' that is a very bad way to think, we actually want to think about this being temporary because it will be."She impressed the importance of vaccines being developed at light speed and suggested those who are anxious about the re-closures should create a game plan."We talk about a cope ahead plan on specific things we can do in lieu of things we are currently enjoying if things shut down again so that we're not disappointed," Dr. Carcel said.She reminded us this is temporary, and we will make it through. 1755

SAN DIEGO (KGTV) - As the number of vaping-related illnesses continues to rise across the country, local leaders are seeing a spike in marijuana vape users in San Diego. The DEA and local health officials are now laying out their plans to stop the crisis in our county. The number of people who have used marijuana vaping in San Diego has grown, including users who are underage. A study done by SANDAG shows 70 percent of juveniles and 61 percent of adults have reported vaping with THC products. The DEA says the best way to combat the spike is to crack down on illegal extraction labs. "The creation of the vaping cartridge process is not controlled in any way, shape, or form," says Assistant Special Agent in Charge Colin Ruane. "There's no quality control; there's no testing of the product. So when you get the THC, you don't know what you're getting and what you're inhaling."The DEA says the extraction of THC also poses a safety risk to the community. Four extraction labs have caused a fire or explosion in various areas around the county. The Center for Disease Control and Prevention has confirmed over 1,800 cases of vaping related illnesses in the U.S. Many of those admitted to using THC products. 37 people have died. The DEA is working with its partners and other local organizations to continue to get the word out on the dangers of vaping. 1368

SAN DIEGO (KGTV) -- City leaders are considering closing some streets in the Gaslamp Quarter to help with social distancing amid the coronavirus pandemic.Pictures on social media showed crowds of people congregating outside bars, many not wearing face coverings, shortly after they reopened Friday.According to a spokesman for San Diego Mayor Kevin Faulconer, the city's department of special events is reviewing a proposal to shut down parts of Fifth Avenue between G and K streets to make it easier to physically distance by providing more room in parts of the public right of way for outdoor dining.The Gaslamp Quarter Association submitted the application, which would close close the streets Thursday, Fridays, and Saturdays. It could be approved and go into effect as soon as this Thursday.Robert Romero owns the Tivoli Bar and Grill. The longtime family-run restaurant on Sixth Avenue reopened Monday. It's the oldest bar in San Diego county."We were open originally in 1881, never have closed in all those years, during the depression, prohibition, World War I, World War Two, until now," said Romero.The owners say they'll be strict about social distancing, face coverings, and increased sanitation protocols."We will have someone at the front door constantly monitoring our customers and making sure they are holding to the restrictions put on us," said Romero.Romero said he noticed many other bars and restaurants were not following the county health orders."It was terrible, when they do that, they're not only reflecting on us, but also putting up the potential for shut down," said Romero.County Health Officials also acknowledged there were problems Friday night after the bars first reopened, but said the city is working to close some streets.California Assemblymember Todd Gloria is also concerned about crowds gathering in the Gaslamp."Part of their reopening is a limited of their capacity, they're operating at a fraction of what they can actually accommodate. Because they were metering the entrance of customers into their businesses, that overflow of customers ends up on the sidewalk," said Assemblymember Gloria.Gloria also thinks closing Fifth Avenue is a good idea."Let's see if there's a way to meet in the middle if you will, these businesses are adhering to the guidelines; the city can certainly help people by closing down the streets, we can be passing out face masks to people who are waiting," said Gloria.Back at Tivoli's, the owners are ready to welcome back customers."Behave, be happy, we love you, they love us and remember, I love it," said Romero, referring to the name Tivoli, spelled backwards. 2648

SAN DIEGO (KGTV) — As the world waits for a vaccine against the coronavirus, two San Diego biotechs are teaming up to develop a nasal spray using designer antibodies cloned from COVID-19 survivors.About 70 companies worldwide are working on therapies for COVID-19 using cloned antibodies, according to an estimate by the International AIDS Vaccine Initiative. A few of these treatments, known officially as monoclonal antibody therapies, have advanced to clinical trials.Most require an injection, but San Diego-based Diomics and its partner Active Motif, based in Carlsbad, are developing a once-a-day spray that could be easily self-administered.Early research suggests the coronavirus primarily enters the body through the nose. The spray, called Dioguard, is designed to coat the lining of the nasal cavity with cloned antibodies that are held in place for 24 hours or more using a proprietary polymer material developed by Diomics.Diomics CEO Anthony Zolezzi said he believes the spray “holds the key to allowing many aspects of life to resume until the day comes when there’s an effective vaccine in widespread use.”Diomics is also developing two tests for COVID-19 antibodies using its polymer beads, including a device that looks like a nicotine patch that is designed to monitor for infections for a week or more.RELATED: How a dot on your forearm could be the future sign of COVID immunityActive Motif is providing the cloned antibodies for the nasal spray. With a lab in Shanghai and other relationships in China, the Carlsbad company was able to clone antibodies from 11 Chinese survivors in February, before the World Health Organization declared a pandemic.When the company started the cloning project, they thought the virus would probably disappear in three to six months, said Active Motif CEO Ted DeFrank. “Then people started realizing, no this is going to be with us for a while.”The plasma from the 11 Chinese patients contained thousands of antibodies, and scientists with Active Motif set about selecting the one that was most effective, dubbed 414-1. The company says it can neutralize SARS-CoV-2 virus particles with 98 percent effectiveness.Monoclonal antibodies have some similarities to convalescent plasma, which is a complex cocktail of antibodies and other immune molecules drawn from the blood of recovered patients. One of the key differences is that cloned antibodies can be mass produced in a lab.Cloned antibodies have been used in treatments for more than 30 years, primarily for cancer. One such treatment famously helped former U.S. President Jimmy Carter beat melanoma.But of the more than 100 monoclonal antibody therapies licensed for use, only seven are for communicable diseases, according to IAVI.Historically, the treatments have been expensive and difficult to produce, but Diomics said it’s targeting a price of about a spray for Dioguard, roughly per bottle.“We do not want to have huge profits from a pandemic, that’s just wrong,” Zolezzi said. “We’re going to price this as effectively as we can for the masses. We want to get this out to the masses.”Animal testing is about to begin and the companies said they hope to progress to human trials soon. Their goal is to release the spray in early 2021, when a vaccine may be on the market but not yet widely available.If the spray works, it could be adapted to other viruses to help fight future pandemics, Zolezzi said."That’s our real goal," Zolezzi said. "That we never get caught flat-footed like this time." 3526

SAN DIEGO (KGTV) – Connecting children, teens, and families to the power of reading has been the mission of San Diego nonprofit Words Alive for more than two decades.During this pandemic, they haven’t skipped a beat.“The San Diego community is so deeply invested in the importance of literacy and just how critical literacy and education are for the success of our students,” said Rachael Orose, Executive Director for Words Alive.Teaching kids reading and writing skills at a young age is key to that success. Orose said through Words Alive, teachers and volunteers are making sure all students have the opportunity and tools to learn through several different programs, including Read Aloud, Teen Services & Family Literacy.“All of the data tells us if we can make you a reader, your family will be a reader. The students who we serve are often in low-income neighborhoods; they’re wrestling with homelessness, hunger, poverty, violence,” she said.This year alone, Words Alive has received thousand of book donations through community partnerships, most recently on Wednesday.“We picked up just over 1,700 books thanks to a partnership with the San Diego Council on Literacy and Houghton Mifflin Harcourt. Those books are zero to 18, they’re headed to the Monarch School in the coming weeks,” she said.“With Words Alive, the books actually belong to the students, they’re able to write in them, they’re able to annotate them” said Jeffra Becknell, who teaches high school history at Monarch School, which serves students K-12 impacted by homelessness. “Having a physical book in their hand is such a wonderful feeling.”Becknell has been participating with Words Alive’s Adolescent Book Group program for ten years. “The Adolescent Book Group has been an amazing experience for my students and me; the volunteers come into the classroom, we read a book together, and then we have a book club discussion about it,” she said.During this pandemic, discussions have moved online, but the mission has remained the same.“We had our Adolescent Book Group online; we had it as a Zoom call. Clearly, it’s really different, but it was the same conversation,” said Becknell.Perhaps most importantly, Orose said Words Alive makes representation a priority.“The content reflects their lived experience, the characters look like the students we serve, the authors have similar experiences,” she said.Words Alive currently has more than 1,000 volunteers but is always looking for more. To find out how you can become involved, click here. 2537