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The 2019 Nobel Prize for Medicine has been jointly awarded to William Kaelin Jr., Sir Peter Ratcliffe and Gregg Semenza for their pioneering research into how human cells respond to changing oxygen levels.Announcing the prize at the Karolinska Institute in Stockholm on Monday, the Nobel committee said that the trio's discoveries have paved the way for "promising new strategies to fight anaemia, cancer and many other diseases."The 2019 medicine laureates, the committee added, have identified molecular machinery that regulates the activity of genes in response to varying levels of oxygen.The importance of oxygen has long been established, the committee explained, but how cells adapt to changes in its levels remained unknown.Randall Johnson, prize committee member, described the trio's work as a "textbook discovery.""This is something basic biology students will be learning about when they study, at aged 12 or 13, or younger, biology and learn the fundamental ways cells work. This is a basic aspect of how a cell works and, from that standpoint alone, it's a very exciting thing."The winnersNew York-born Kaelin established his own research laboratory at the Dana-Farber Cancer Institute in Boston and became a full professor at Harvard Medical School in 2002.Semenza, also born in New York, became a full-time professor at Johns Hopkins University in 1999 and since 2003 has been the Director of the Vascular Research Program at the Johns Hopkins Institute for Cell Engineering.Ratcliffe, who was born in Lancashire, England, studied medicine at Cambridge University and established an independent research group at Oxford University, becoming a full professor in 1996. 1694
The Office of Refugee Resettlement, which is charged with caring for unaccompanied migrant children, is "scaling back" or canceling activities at shelters, citing the need for more resources.A swell of migrants crossing the southern border has overwhelmed the agency's facilities, which house unaccompanied children until they are placed with a sponsor in the United States. The shelters provide schooling and activities for the children during their stay, but the increase of children arriving to the border has strained the department's resources."This week, ORR instructed grantees to begin scaling back or discontinuing awards for (unaccompanied minors) activities that are not directly necessary for the protection of life and safety, including education services, legal services, and recreation," Evelyn Stauffer, spokeswoman for the Department of Health and Human Services' Administration for Children and Families, said in a statement.The Washington Post 975
The Kansas City Chiefs have earned a spot in Super Bowl 54 in two weeks, defeating the Tennessee Titans 35-24 on Sunday. The Chiefs are making their first Super Bowl appearance in over 50 years. The Chiefs last played for a Super Bowl following the 1969 season, defeating Minnesota.By defeating the Titans, the Chiefs earn this season's AFC title. Quarterback Patrick Mahomes, the third-year quarterback from Texas Tech, completed 23 of 35 passes with three touchdowns. He also carried the ball seven times for 54 yards and a touchdown. Andy Reid, who is No. 7 on the all-time wins list, will coach in his second Super Bowl, and his first since winning the Super Bowl 15 years ago.Kansas City will play the winner of the NFC title game being played between Green Bay and San Francisco Sunday evening. The Chiefs rallied after trailing by scores of 10-0 and 17-7 in the first half. The Chiefs closed out the first half with back to back touchdowns to take a 21-17 lead at halftime. After a scoreless third quarter, the Chiefs once again scored back to back touchdowns in the fourth quarter to put the game out of reach with a 35-17 lead. Tennessee scored with a touchdown with 4:18 left, but the touchdown came too late for the Titans to mount a comeback. 1267
Thank YOU @ThomasRhett for such a special speech last night ??Catch up on #CMTAOTY on demand now! pic.twitter.com/O5TPSIsRbW— CMT (@CMT) October 17, 2019 165
The City of New Orleans is asking citizens not to share photos of the exposed remains of a construction worker that died in a building collapse in October.The Hard Rock Hotel in New Orleans' French Quarter, which was under construction at the time, 261