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Older women with excess body fat, even if they have what's considered a normal body-mass index, could be at greater risk for breast cancer, according to a study published Thursday in the medical journal JAMA Oncology."We do find that excess body fat in those who are post-menopausal with a normal body mass index is associated with about a doubling in the risk of estrogen-dependent breast cancer," said Dr. Andrew Dannenberg, one of the study's authors and director of cancer prevention at the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine.The American Cancer Society says estrogen-dependent cancers, called ER-positive breast cancer in the study, occur when the receptor proteins in or on cells attach to the hormone estrogen and rely on it to grow.The researchers studied 3,460 American women between the ages of 50 and 79 who had gone through menopause. The women were part of the Women's Health Initiative and had their body composition measured at the beginning of that program, Dannenberg said. Of those women, 146 developed ER-positive breast cancer, and the researchers looked for a relationship between excess body fat and the development of this cancer. 1190

Officials at the Hermitage — the site of former President Andrew Jackson's former plantation home in Tennessee — have reported that Jackson's tomb has been vandalized.The incident was reported to the Metro Nashville Police Department. Vandals allegedly covered the tomb of Jackson and his wife Rachel Jackson with profanities in black and red spray paint.They posted the incident to the Hermitage Facebook page: 444

OCEANSIDE, Calif. (KGTV) - Therapy dogs are tasked with healing patients who are up against diversity. But two who walk the halls of Tri-City Medical Center have their own stories of survival."I think every one of us, animal or human, has our own story. We all have our trials and tribulations. And so I think having animals that have been through some difficult times helps them relate with our patients in a much more profound way," said Aaron Byzak, Chief External Affairs Officer for Tri-City Medical Center.Two veterans of the Pet Therapy Program are Prince the poodle and Calamity Jane the golden retriever, one a cancer survivor and the other a trauma survivor. "She's a very strong, strong, little pup, she's got a mind of her own," said Shar Pauley, who rescued Calamity Jane. "And she tells me which rooms she'd like to visit. Sometimes she'll walk down that hallway and then she'll stop and say I think this person needs a visit." The program has been comforting patients for over 20 years now."He's had nine lives, and I think part of his motivation for giving back is he just loves to work, and he loves people," said Mary Gleisberg, Prince's owner. The dogs must go through a rigorous process to earn their badge and must receive a bath before walking their rounds in the hospital. 1304

On Friday, roughly 900 million miles away, a collection of metal and electronics will crash into Saturn, disintegrating into its atmosphere. It sounds almost routine -- or at least a mere blip on the radar of importance for people grappling with hurricanes, war and political discord.But it's not routine. At least not for the more than 5,000 people who, at one time or another, worked on the Cassini spacecraft mission. For them, it's a thrilling -- and perhaps traumatic -- end to a decades-long journey."I'm now carrying around an end-of-mission handkerchief to every interview," said Trina Ray, Cassini's Science Planning and Sequencing Team deputy. She joined the mission just before its launch in 1997. "It's part of being a part of an incredible thing, and of course, everybody is so proud of the team, of the spacecraft. There's a lot of pride in what we've done." 880

ORANGE, Calif. - As Amtrak prepares for the busiest travel period of the year, the company is adding railcars and requiring reservations for passengers. Due to increased crowds for holiday travel, Amtrak is encouraging passengers to plan ahead and book early. Reservations will be mandatory between Wednesday, Nov. 27 and Monday, Dec. 2. Metrolink and COASTER passes will not be accepted onboard Pacific Surfliner trains during this time, however Amtrak monthly and 10-ride passes may still be used. Additionally, the Rail 2 Rail program will be suspended during these dates. The Pacific Surfliner route travels between San Diego, Orange County, Los Angeles, Ventura, Santa Barbara, and San Luis Obispo. It offers a total of 26 trains a day between Los Angeles and San Diego. All Pacific Surfliner trains feature reclining seats, power outlets, Wi-Fi, bike and luggage racks, and a cafe that offers food and drinks, including alcoholic beverages. Coach tickets guarantee a space on the train while Business class passengers are guaranteed a seat. Tickets and reservations are available on PacificSurfliner.com, Amtrak.com, Amtrak mobile apps, or by calling 800-USA-RAIL. 1179