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The US Food and Drug Administration expanded?the list of drugs being recalled that contain valsartan. The drug is used as a component in a set of drugs used to treat heart failure and blood pressure.New to the list are some valsartan products manufactured by Hetero Labs Ltd. in India, which are labeled as Camber Pharmaceuticals Inc. Test results show that some of the products may be tainted.The FDA announced a valsartan recall in July after lab tests revealed that some drugs could have been tainted with a substance linked to higher risk of cancer. The drug had been recalled in 22 other countries. The expanded recall includes some drugs that contain valsartan and hydrochlorothisazide. Not all of the drugs containing valsartan were affected.N-nitrosodimethylamine or NDMA, the impurity the lab tests found, is considered a?possible carcinogen by the US Environmental Protection Agency. It is an organic chemical that has been used to make liquid rocket fuel, and it can be unintentionally introduced through certain chemical reactions. It's a byproduct of the manufacturing of some pesticides and fish processing.The medicines that are now a part of this expanded list?in the recall are tablets sold by AvKare, A-S Medication Solutions LLC, Bryant Ranch Prepack Inc, Camber Pharmaceuticals, Inc. H J Harkins Company, Northwind Pharmaceuticals, NuCare Pharmaceuticals Inc., Prinston Pharmaceutical Inc. (labeled as Solco Healthcare LLC), Proficient Rx LP, Remedy Repack, Teva Pharmaceuticals (labeled as Major Pharmaceuticals), Teva Pharmaceuticals USA (labeled as Actavis).The FDA also published a list of valsartan products that are not currently recalled. Only the drugs suspected of being tainted with NDMA are on the recall list. If you are taking a valsartan drug, look for the company name on your prescription bottle. If the information isn't on the label, you can call your pharmacy for those details.The recalled medicine is linked to a manufacturer in China. The substances were supplied by Zhejiang Huahai Pharmaceuticals, based in Linhai, in eastern China, which said it notified authorities as soon as it identified the impurity."We published our recall notice at midday on July 13 in China and overseas, and published the US market recall notice on July 14 Beijing time ... all the drug materials for the Chinese market were recalled by July 23," the company said in a statement to the Shanghai stock exchange last month.The FDA said on its website that it's working with drug manufacturers "to ensure future valsartan active pharmaceutical ingredients are not at risk."If you are worried that your drug could be on the recall list, talk with your doctor or pharmacist before changing any routine with your medicine. Because not all valsartan drugs are involved in the recall, they might be able to switch you to a version of the drug made by another company.If you know your drug is on the recall list, the FDA suggests you continue taking it until your doctor or pharmacist provides a replacement.To get a sense of what taking a tainted drug could mean, FDA scientists estimated that if 8,000 people took the highest dose of valsartan (320 milligrams) from the recalled batches every day for four years, there may be one additional case of cancer."The key with this is, patients should not stop taking their medication abruptly, that definitely can be harmful," Dr. Mary Ann Bauman, a representative for the American Heart Association, said in July. "You don't want to jump to any conclusions on your own about this medication, or any medication for that matter. Definitely talk with your doctor first." 3690
The weather at the beginning of November and the end of October are going to look very different across the country.Temperatures in the eastern half of the country, except the Northeast, took a big drop and even saw some snow. At the same time, the West Coast was dealing with some record-breaking heat. 311
The world's largest Lego replica of the doomed Titanic liner was built over 700 hours -- 11 months -- by a 10-year-old boy from Reykjavik, Iceland, who is on the autism spectrum.It will make its American debut Monday at the Titanic Museum Attraction in Pigeon Forge, Tennessee.Brynjar Karl Bigisson, now 15, built the replica with 56,000 Lego bricks. It's 26 feet long and 5 feet tall.Brynjar remembers playing with Legos for hours when he was 5. "I sometimes built from instructions, and sometimes, I used my own imagination," he said.At the time, he was obsessed with trains, but that changed when his grandfather Ludvik Ogmundsson took him fishing on a boat, sparking an interest in and appreciation for ships. By the time Brynjar was 10, he knew everything there was to know about the Titanic."When I traveled with my mom to Legoland in Denmark and saw for the first time all the amazing big models of famous houses and planes, locations and ships, I probably then started to think about making my own Lego model. By the time I was 10, I started to think about building the Lego titanic model in a Lego man size," Brynjar said.The project was a family affair, with grandfather Ogmundsson, an engineer, and mother Bjarney Ludviksdottir helping out. Ogmundsson scaled down the original blueprint of the Titanic to Lego size and helped figure out how many tiny toy bricks would be needed to create the model.Ludviksdottir served as his personal cheerleader. "If she had not supported my dream project, it would have never been a reality," Brynjar said.Donations from family and friends enabled him to buy all the Lego bricks.Brynjar says he was able to embrace his autism through building the Titanic replica.Before starting the project, he had difficulty communicating, which he says made him unhappy and lonely. Now, he has confidence and is giving interviews about his accomplishment."When I started the building process, I had a person helping me in school in every step that I took, but today, I'm studying without any support. My grades have risen, and my classmates consider me as their peer. I have had the opportunity to travel and explore and meet wonderful people," he said.Brynjar's mother said that when she started raising her son, she felt totally blind as to what his future would look like because of his autism, and she worried about the obstacles that many children on the autism spectrum have to overcome. She is now proud to share with other parents of children on the autism spectrum that it is possible to achieve their goals."When your child comes to you with an interesting big crazy dream, mission or goal, he or she would like to reach and needs your help. Listen carefully and make an attempt to find ways to support the child to reach that goal. It might be the best investment you ever make for your kid," Ludviksdottir said.She believes it can be hard for children to follow their dreams, whether they are on the autism spectrum or not. They may face financial hindrances or lack of support. But she believes in the significance of dreams."Dreams keep us going. That is something nobody can take away from us. It's something good to have when you are feeling a little bit stuck or sad. You can always dream."The Lego replica was shipped from Iceland in three large pieces and then carefully reconstructed before its American debut. It will be anchored at the Titanic Museum Attraction through December 2019.Brynjar's grandfather said he believes there are lessons to be learned from what his grandson has achieved."Autism does not have to be scary. Many great scientists and national leaders had and have autism. What matters is that such individuals get understanding and support, because everyone can learn from these people if they listen to what they are saying," Ogmundsson said"When Brynjar was growing up, I often helped him with projects that called for thought and hard work that I thought would be good for him. Then he got this crazy idea to build a 6-meter ship from Lego cubes. Today he speculates a great deal about complex things that require technical understanding."The-CNN-Wire 4135
The Trump administration is planning to expand an operation that would send federal law enforcement agents to Detroit, Cleveland and Milwaukee in the coming weeks, the White House announced Wednesday night.According to a recap of the day's events on the White House website, President Donald Trump and the Department of Justice plan to expand the program into the three Midwestern cities in the next three weeks.Trump and Attorney General William Barr announced Wednesday that they would send federal agents to Chicago and Albuquerque to combat rising crime under the "law and order" push.“In recent weeks there has been a radical movement to defund, dismantle and dissolve our police department,” Trump said Wednesday at a White House event, blaming the movement for “a shocking explosion of shootings, killings, murders and heinous crimes of violence.”“This bloodshed must end,” he said. “This bloodshed will end.”Detroit Mayor Mike Duggan, Police Chief James Craig and Michigan Gov. Gretchen Whitmer spoke out earlier this week after Trump said they were looking into the plan to bring agents to Detroit."There could be no possible justification for such an action. The Detroit Police Department has had the support of the Detroit community in making sure our City did not have a single store looted or a single fire started during the protests," Duggan and Craig said in a joint statement. "Unlike nearly every other major city in the country, the Detroit Police Department never requested assistance from the National Guard - we handled our issues as a community. We definitely have no need for any federal presence being sent in now.""It is deeply disturbing that President Trump is once again choosing to spread hateful rhetoric and attempting to suppress the voices of those he doesn't agree with," Whitmer said. "Quite frankly, the president doesn't know the first thing about Detroit. If he did, he would know that for nearly two months now, Detroiters have gathered to peacefully protest the systemic racism and discrimination that Black Americans face every day. There is no reason for the president to send federal troops into a city where people are demanding change peacefully and respectfully."Federal officers are already in Portland, Oregon and have clashed with protesters over the previous few days."Portland is a very different place than Chicago, but Chicago should be calling us, and so should Philadelphia and Detroit and others to go in and really help them," he said. "Because when you're losing many people a weekend... you see the same numbers as I do. When you're losing these people they should call us and they should say come on in. It's incredible to me, but they're not doing it. At some point they will; at some point we may have no other choice but to go in."This story was originally published by Max White at WXYZ. 2860
The world is in the midst of a pandemic. While it's important to stay informed, and up-to-date on the latest COVID-19-related news, it's also OK to take mental breaks.Video games are among the best forms of entertainment to help provide an escape. Here are nine titles to help ease your stress.Animal Crossing: New Horizons(Nintendo Switch) KGUN's review 362