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Pfizer announced Monday that its COVID-19 vaccine candidate has been 90% effective.In a press release, the company said that in Phase 3 trials, the vaccine has proven to promote a vaccine efficacy rate above 90% following the two-shot regimen.The Associated Press said that while Pfizer's announcement means the company is on track to file an application for emergency use authorization later this month, it does not mean a vaccine is "imminent" and more studies are needed.Pfizer's vaccine candidate began Phase 3 testing in the summer and is among a handful of vaccine candidates that could be distributed in the coming months pending FDA approval.Phase 3 trials consist of testing about 30,000 voluntary participants in a double-blind study — meaning half of those participating receive the vaccine, and half receive a placebo. Pfizer's vaccine requires two shots, which need to be taken 28 days apart.According to Pfizer, 90% of those who were tested for the vaccine had developed protection against the virus seven days following the second shot.Pfizer is already in the process of producing millions of doses of its vaccine candidate after the U.S. government agreed to pay .95 billion for 100 million doses of the vaccine, should it prove effective. If and when the FDA grants approval for the vaccine, it will be distributed to hospitals around the country by the U.S. military in an effort the Trump administration has dubbed "Operation Warp Speed.Even though hundreds of thousands of doses of the Pfizer vaccine will be ready for shipment if it is approved for emergency use, it will need to be rationed in the first months of its availability. According to a playbook for "Operation Warp Speed," essential health care workers and people in high-risk populations would have the first opportunity to get a COVID-19 vaccine. The rest of the general public will be able to get the vaccine as more doses become available later in 2021.Pfizer was one of a handful of companies that pledged in September not to distribute their vaccine under political pressure, and would only do so if it proved to be effective in large scale trials.Monday's announcement sent stock market futures through the roof, as investors eyed a return to economic normalcy should Pfizer's vaccine be given emergency approval in the coming days or weeks.President Donald Trump also celebrated the announcement in a tweet on Monday morning."STOCK MARKET UP BIG, VACCINE COMING SOON. REPORT 90% EFFECTIVE. SUCH GREAT NEWS!" Trump tweeted. 2524

Parents are still confused about why dozens of Wisconsin students got sick in March.Jesse Coates's 13-year-old daughter went to the emergency room after passing out at the Oconomowoc Arts Center in Oconomowoc, Wisconsin. She's one of the 200 students who mysteriously got sick at Oconomowoc High School and the Oconomowoc Arts Center in March."They were told that it was potentially a CO leak and that's why they were evacuating the building," Coates said.But the Oconomowoc Area School District said it wasn't carbon monoxide."There's just a lot of unanswered questions," Coates said. "You don't want to see it happen again," he said.Even other school districts have taken notice. After seeing the news, Wauwatosa decided to take action in case they ever do have a real carbon monoxide leak.Some schools in Wisconsin are installing CO2 detectors, even though they are not required by law."It's just one more step we can do to ensure the safety of our students," said Melissa Nettesheim, the manager of building and grounds for Wauwatosa School District.At about each and less than 10 minutes to install, Nettesheim said the district is putting at least one carbon monoxide detector in each of its buildings."All the alarms are in place in case carbon monoxide levels did reach a level that would require us to evacuate the building," Nettesheim said.She said that's never happened. And that it's a proactive measure not required by law.Wisconsin state law says "the owner of a residential building shall install a carbon monoxide detector in all of the following places."All of the listed locations are residential. Nothing in the law talks about schools.Wisconsin's largest school district, Milwaukee Public Schools, doesn't have carbon monoxide detectors.Oconomowoc's high school has detectors that "would alarm in the presence of carbon monoxide."Coates still feels uneasy."What caused my daughter and all her friends to get sick?" he wondered out loud. "That's the number one concern from all the parents," Coates said. 2041

PALA MESA, Calif. (KGTV) -- A 5-year-old boy critically injured in Saturday’s deadly bus crash was airlifted to a Riverside County hospital Sunday, authorities said. The young boy was airlifted from Inland Valley Medical Center to the Riverside University Health System Medical Center in Moreno Valley to be treated for a head injury, California Highway Patrol Officer Mark Latulippe said. The boy was among 21 passengers on a charter bus traveling to Tijuana from El Monte. The crash happened on Interstate 15 south of State Route 76. Three women were killed in the crash that left 18 others hospitalized. Five of those injured were taken to Palomar Medical Center in Escondido, five to Inland Valley Medical Center in Wildomar and eight to Temecula Valley Hospital, Latulippe said. RELATED: At least three dead, 18 injured in bus rollover on Interstate 15Three passengers suffered major injuries, Latulippe said, and officials were determining the other injured patients' conditions Sunday morning.The crash happened around 10:30 a.m. Saturday when the charter bus owned by Executive Lines Inc. slid off the 15 during heavy rain. The bus then continued down an embankment before landing on its roof, ejecting several passengers. A vehicle inspection report dated November 5, 2019, shows that, as of that date, the windshield wipers were either inoperative or defective. The same report shows that the vehicle had no spare fuses “as required.” A second report of the bus line revealed that 48 percent of vehicles in that particular safety group have better on-road performance. The review also showed no “acute/critical violations discovered.”City News Service contributed to this report. 1698

PINE VALLEY, Calif. (KGTV) -- After Larry McNamer received a cease-and-desist letter from San Diego County officials, during the first week purple tier restrictions went into place, he said he will not back down."This is what courts are for. I'll fight it, I will fight it," the owner of Major’s Diner in Pine Valley said.In the letter, county officials noted he could face up to a ,000 fine for every violation under the state's guidelines, which includes not allowing guests inside."It could be ,000. I don't care because I can't afford to pay it, so I couldn't pay it if I had to,” McNamer told ABC 10News.McNamer said it all boils down to survival of this business and what he thinks is right in an uphill battle with the county and the state."They're going to have be a lot more fair about doling this out and understand that we zero cases up here [in Pine Valley],” he said.Even as he continues to serve up hot plates inside, McNamer said nothing changes when it comes to safety measures given by the state. He said guests are sat apart inside and have the option of dining outdoors if they choose.ABC 10News caught up with a couple from Alpine who grabbed a bite to eat Friday morning, not because Major's was the only diner open but they wanted to support him after seeing him on ABC 10News newscasts."We saw they were in trouble and in need of assistance, so we came to support them,” the supporter, Mark, said.ABC 10News asked Mark and his wife if they thought customers supporting restaurants who defy public health orders are contributing to the problem of COVID-19 cases rates surging, as restrictions continue to grow."Show me the data that these are sources of community spread because the data I see doesn't show that,” Mark said.McNamer said he's been receiving postcards and letters from people across the county supporting his choice of staying open to survive."It empowers you, it lets you know you're doing the right thing,” he said. 1967

PASADENA, Calif. (CNS) - With the coronavirus pandemic still raging in Southern California, the 2021 Rose Parade was officially canceled Wednesday, but the fate of the Rose Bowl Game remains in limbo."The health and well-being of our parade participants and guests, as well as that of our volunteer members, professional staff and partners, is our number one priority," Bob Miller, president of the Pasadena Tournament of Roses Association said in a statement. "Obviously this is not what any of us wanted, and we held off on announcing until we were absolutely sure that safety restrictions would prevent us from continuing with planning for 132nd Rose Parade."It's only the fourth time since 1891 that the parade has been canceled, with the three previous cancellations occurring during the wartime years of 1942, 1943 and 1945.Although the New Year's Day tradition was technically still months away, planning for the elaborate floral floats that highlight the event -- and arranging for the often international travel of participating marching bands and equestrian groups -- is a nearly yearlong process, necessitating an early decision on whether to hold the event. Tournament of Roses officials noted that the state's economic-reopening guidelines appear to be a long way off from permitting large public gatherings such as a parade.David Eads, Tournament of Roses executive director/CEO, said planning is continuing for the Rose Bowl Game, but uncertainty still looms over the college football season."We continue to work with the College Football Playoff and our collegiate partners to explore what this year's college football season will look like amidst COVID-19 and social distancing guidelines," Eads said in a statement. "While the safety and well-being of the student athletes, university personnel and fans is our top priority, we remain hopeful that the `Granddaddy of Them All' will take place on New Year's Day."Pasadena Mayor Terry Tornek called the decision "extremely disappointing.""However, we also know that we must act responsibly to protect our community in the face of the COVID-19 pandemic," Tornek said. "We look forward to working with the Pasadena Tournament of Roses on their re-imagined New Year celebration, as well as the return of the Rose Parade on January 1, 2022."Tournament of Roses officials said they are working to develop plans for a "new kind of New Year celebration" for fans of the annual parade."Each year, the country turns its eyes to Pasadena for America's New Year celebration and we plan to deliver on that important promise," Eads said. "We may not be able to host our traditional five-mile march down Colorado Boulevard, but we are exploring new and safe ways we can collectively share in the celebration, and we look forward to announcing further details about our exciting new plans in the coming weeks." 2869