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SINGAPORE, Sept. 7 (Xinhua) -- Singapore scientists have found possible new ways to treat a type of aggressive breast cancer that is unresponsive to current forms of treatment, local broadcaster Channel NewsAsia reported on Wednesday.The team of scientists at the Genome Institute of Singapore ( GIS) and National University of Singapore (NUS), led by GIS senior group leader Qiang Yu, found that the enzyme EZH2 acts by inhibiting genes that stop the growth of tumors in the body.The insights could open the door to developing more effective treatment for fast spreading breast cancers, especially the estrogen receptor-negative breast cancer that is common all over the world.It was also found that through EZH2, cancer is promoted in the body by activating specific genes that impact breast cancer progression and cancer stem cell self-renewal.Yu said the new understanding on how EZH2 works as a cancer- causing gene in breast cancer has important therapeutic implication."The results suggest that small molecule drugs that block enzyme activity of EZH2 may not work for cancers caused by EZH2's activation genes," Yu said.Currently pharmaceutical companies have been developing drugs only to the block EZH2 enzyme activity so that tumor suppressers can perform their protective role in blocking cancer growth.Researchers said the next step would be to develop biomarkers to identify tumors with EZH2.This step would enable better treatment methods, with one of options being the development of therapies that shut down EZH2 completely and not just inhibit its enzymatic function.The findings have been published on the journal Molecular Cell.

BEIJING, July 14 (Xinhuanet) -- European music service Spotify is set to launch in the United States on Thursday, according to media reports.The streaming service will be available in the morning by invitation and through subscription."Spotify is a new way to listen to and manage your music, discover new tracks and share songs and playlists with friends – music whenever you want it, wherever you are," the company said in a statement.Spotify's streaming music and subscription service have long been popular in Europe since its launch in late 2008, and the company has been aiming for a US launch for nearly as long.Spotify has inked agreements with Sony Corp Music Entertainment, EMI Music, and Vivendi SA's Universal Music Group in the last few months. It is expected to close a deal with Warner Music Group by launch or soon after, according to a source.

BEIJING, Sept. 26 (Xinhua) -- Nobel laureates on Monday cast doubt on a European experiment that purportedly demonstrated the ability of neutrinos to move faster than the speed of light.They made the remarks in Beijing prior to a forum for Nobel laureates."I'm willing to bet money that it's not correct," said Professor George Smoot III, winner of the 2006 Nobel Prize in Physics and a professor at University of California, Berkeley, referring to an experiment result claiming that particles apparently travel faster than light.The experiment reported an anomaly in the flight time of neutrinos, or electrically neutral subatomic particles, from the European Center for Nuclear Research (CERN) in Switzerland to a laboratory located 730 kilometers away in Italy.Particles were clocked transmitting at a speed of 300,006 kilometers per second, about 60 nanoseconds faster than the speed of light.Smoot said that the claims "did not make sense" and should be verified by other scientists first."There are many distortions in physics. You have to have a very high standard to see if something is truly correct," he said.The unverified findings were published on Sept. 22 in the scientific journal Nature. European researchers working in a team called OPERA (Oscillation Project with Emulsion-Racking Apparatus) projected masses of neutrinos from CERN and then collected the particles using a massive detector in Gran Sasso, south of Rome.Other scientists, as well as the OPERA team themselves, have voiced doubts regarding the experiment's results.The findings, CERN claims, could pose far-reaching potential consequences once verified.If correct, the results would bring Einstein's theory of special relativity into question. Under this theory, a physical object cannot travel faster than the speed of light in a vacuum."If really it is right, we have to rethink everything we know," said Chris Llewellyn Smith, former director of CERN.Smith claimed the unprecedented discovery was too exceptional to find proof."If somebody makes a very exceptional claim, then very exceptional proof would need to come from another experiment, saying the same thing. But we don't have the other thing," Smith said.Carlos Rubbia, a Nobel Laureate who won the prize for physics in 1984, is in charge of a team of more than 100 scientists at CERN."What it is pretending to find, in my view, is unbelievably surprising," Rubbia said."Frankly, I have the feeling that this is still a very experimental consideration," Rubbia said.He also believes that revealing the findings to the public was a mistake as it remained an experimental process and no conclusion could be drawn without the results of another experiment.Despite the possibility of verification, Einstein's special theory of relativity will remain valid."I will be very, very surprised that, at last, Einstein will not be the winner," Rubbia said.To achieve a breakthrough, Rubbia has urged for more joint cooperation on verifying the test results. International cooperation on this issue "is a must.""It requires coordination from all nations," said Rubbia.The 2011 Nobel Laureates Beijing Forum will be held from Sept. 28 to 30 under a theme of "innovation and development."

WASHINGTON, July 18 (Xinhua) -- Exposure to secondhand smoke ( SHS) is associated with increased risk of hearing loss among adolescents, according to a report in the July issue of Archives of Otolaryngology -- Head and Neck Surgery.Among U.S. children, approximately 60 percent are exposed to SHS, according to background information in the article. Studies have associated exposure to secondhand smoke prenatally or during childhood with various health conditions, from low birth weight and respiratory infections to behavioral problems and otitis media. Children exposed to SHS are more likely to develop recurrent otitis media, the authors note. "Secondhand smoke may also have the potential to have an impact on auditory development, leading to sensorineural hearing loss (SNHL)," they add.Anil Lalwani and colleagues from New York University Langone Medical Center examined the risk factors for SNHL, including SHS, among adolescents, stratified by demographic groups. They included 1,533 individuals from 12 years to 19 years of age who participated in the National Health and Nutrition Examination Survey from 2005 to 2006.Participants were interviewed about their health status and family medical history, exposure to SHS, and self-recognition of hearing impairment. In addition, they underwent a physical examination, including blood testing for cotinine (a by-product of nicotine exposure), and hearing tests.Compared with teens who had no SHS exposure, those who were exposed to secondhand smoke exhibited higher rates of low- and high-frequency hearing loss. The rate of hearing loss appeared to be cumulative, increasing with the level of cotinine detected by blood tests. The results also demonstrated that more than 80 percent of participants with hearing loss did not realize they had impairment.As hearing loss early in life can cause problems with development and functioning, the authors suggest that these results have "significant implications for public health in the United States."They note that most adolescents do not receive screening for hearing loss in the absence of risk factors.If further studies replicate these results, they state, SHS could be considered one such risk factor.

WASHINGTON, July 27 (Xinhua) -- The solar-powered, Jupiter- bound Juno spacecraft was secured into place on top of its rocket Wednesday in preparation for launch next month, the U.S. National Aeronautics and Space Administration (NASA) announced.The launch period for Juno opens Aug. 5 and extends through Aug. 26. For an Aug. 5 liftoff, the launch window opens at 11:34 a.m. EDT (1534 GMT) and remains open through 12:43 EDT (1643 GMT).Juno will arrive at Jupiter in July 2016 and orbit its poles 33 times to learn more about the gas giant's interior, atmosphere and aurora."We're about to start our journey to Jupiter to unlock the secrets of the early solar system," said Scott Bolton, the mission 's principal investigator from the Southwest Research Institute in San Antonio. "After eight years of development, the spacecraft is ready for its important mission."

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