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Losing a child to an undiagnosed heart condition is, in so many words, heartbreaking. But doctors may be close to preventing one type of heart disease before it even starts. It's giving hope to families fighting to overcome tragedy.Lisa Pardington's son Max was training for an Iron Man competition the day she last heard his voice."I called after he had worked out and he said, 'Mom my heart is racing,'" Pardington remembers. "And those words changed my life forever."That night Max went to sleep and never woke up."It's the worst day," Pardington says. "It's every parent's nightmare and we are living it every day."Max had cardiomyopathy, a disease in which the heart muscle is abnormally enlarged, thickened or stiffened. It's often genetic and is the most common cause of sudden death in young athletes."He played all kinds of sports but never did we know that Max had a heart condition until he passed away," Pardington says.Since most school physicals don't check for it, Beaumont Health organized a free Student Heart Check where doctors and volunteers are screening teens for the disease, before it's too late."It makes you feel good about what you do because I know we have saved lives coming to these events," says Beaumont cardiologist Dr. Steven Almany.Lori Herbert lost her son Anthony to the disease, and decided to become active in the program."I know if he could he would want us to save lives," Herbert says. "Not a minute goes by that I don't think of him."Anthony was a member of the Northern Michigan University football team when he passed away."He had just come back from conditioning that morning, went to breakfast and then went back to his dorm with his roommate and was going to watch a movie before their first day of classes," Herbert says. "And that's when he became unresponsive and went into sudden cardiac arrest." First responders tried to save him but couldn't."It didn't feel real," Herbert says. "It was just a nightmare. I mean he was eight hours away from us and there was absolutely nothing we could do."Herbert says they had never heard of the screenings done at the Student Heart Check during any physicals. That's why they hope heart check events like these spread to other cities across the country. "We knew we couldn't bring Anthony back but we wanted to hopefully keep other parents from having to endure what we had to endure," Herbert says. "I'm not going to lie, I wish that we could've gotten him to a screening and still had him here with us."But what if there were a way to prevent cardiomyopathy in children in their mother's womb before it even started to develop? Doctors at the Oregon health and Science University began researching that possibility.Dr. Sanjiv Kaul worked with researchers who were able to cut out the defective gene when they fertilized an egg in a lab."Yes everybody here was surprised," says Kaul, CEO of the Knight Cardiovascular Institute. "Then the cells repaired normally by themselves. We were amazed. It's like science fiction."While it hasn't been tested in humans, Kaul says potentially all cells after that one would be free of the abnormal gene."So, theoretically, in one generation we can remove this defect from the entire generation."While there's concern this technology could be used to create so-called "designer babies," Kaul believes with regulation, the research offers hope."Talking to a parent that lost a child I would have done anything in the world to save my son's life," Pardington says.Adding one more layer to the effort to keep children healthy and alive. 3620

Melania Trump says she and President Donald Trump have faith in judges and the legal system to rule justly -- a statement that appears out of step with the president.At an event Monday in Pennsylvania, the president assailed as “very dangerous” a decision by Pennsylvania’s top court to allow mailed ballots received in the three days after Tuesday’s election to be counted.Later Monday, the first lady addressed a Trump rally in Huntersville, North Carolina. She expressed faith in the doctors, nurses, and scientists working on the coronavirus pandemic.Trump suggested Monday that he might fire Dr. Anthony Fauci after the election.Trump has disagreed with pandemic advice from Fauci, the nation’s leading infectious-disease expert and member of the White House coronavirus task force. 795

MATIAS ROMERO, Mexico (AP) — Dozens of transgender women and gay men in the caravan moving through Mexico with hopes of seeking asylum in the United States have banded together for protection — not from the uncertainty of a journey fraught with danger from the gangs who prey on migrants but from their fellow travelers.Fleeing violence and discrimination back home because of their gender identity or sexual orientation, these LGBTQ migrants have found the journey north to be just as threatening amid catcalls and even physical abuse."Sweet little thing!" ''Baby, where you going?" ''How much do you charge?" These all-too-familiar jeers are spewed at them as they make their way with the caravan of several thousand.Loly Mendez, a 28-year-old who began transitioning to a woman in her native El Salvador, knows all too well the dangers her fellow transgender migrants faced back home: Her best friend, also a transgender woman, was murdered for doing the same.RELATED: Interactive map: Migrant caravan journeys to U.S.-Mexico borderThen Loly herself began getting threats — "that if my breasts were going to grow, they would cut them off," she said. They were always anonymously delivered, which only made her more fearful and finally drove her to flee."In my country there is violence, a lack of work and opportunities," said Loly, who like many of the transgender women in the group preferred using only her first name. "In the caravan there is also violence — against the LGBTQ community."Loly linked up with the caravan in Tapachula, in southern Mexico, and hopes to work in the United States and save up to start a beauty products company — perhaps in Los Angeles or New York. It's something she has planned for a long time, all the way down to the business' logo, but she's never had the money."I am going to a country where I know I will achieve my dreams," Loly said, hopefully.Reports are common in much of Central America of LGBTQ people being murdered, assaulted and discriminated against, due to their gender identity or sexual orientation.But getting U.S. asylum is difficult even with proof someone has been the victim of persecution for being transgender, said Lynly Egyes, director of litigation at the Transgender Law Center in Oakland, California.It often takes days or weeks for transgender immigrants to get a hearing before an asylum officer. If they are allowed to move forward in the process, many are traumatized and struggle to tell their story, Egyes said. They are also much less likely to be granted asylum without a lawyer."It is a horrifying process, and not everybody makes it through," she said.Many of the migrants have said they joined the caravan because it offered safety in numbers. The 50 or so LGBTQ migrants traveling together, most of them in their 20s but some as young as 17 or as old as 60, say they, too, banded together for safety — a sort of caravan within the caravan.Sticking out in their bright-colored clothing and makeup, the group has suffered verbal harassment, especially from men, and has been the victim of robbery and other aggressions. One recent day as they walked in a row on the highway to Isla, in the Mexican Gulf coast state of Veracruz, a group of fellow migrants passed by on a flatbed truck and showered them with water, oranges, rinds and other refuse.Fearful of being attacked more violently or sexually assaulted, they stick by each other's sides 24 hours a day, walking and sleeping in a group and even using the buddy system for going to the bathroom.In Matias Romero, in the southern Mexican state of Oaxaca, rather than sleep outdoors they took over an abandoned hotel damaged in last year's deadly earthquake. Dirty, windowless and with no electricity or running water, it was nonetheless a place to have a roof over their heads and be safe. They bathed by the light of a small lantern, dressed themselves and applied makeup as dozens of men milled about outside.Each night "the girls," as they call themselves, sift through piles of donated clothing to try to look as sharp as possible. And they face a dilemma: Where to dress and relieve themselves?"We have problems when it comes time to go to the bathroom," said Nakai Flotte, a transgender woman and activist. "We bathe in the men's, sometimes in the women's, but it's difficult. There isn't one for us."Flotte was accompanying the migrants to provide support and information about making asylum claims.The U.S. "should take into account their condition of vulnerability and violence," she said.However, a decision by then Attorney General Jeff Sessions this year to deny asylum to victims of domestic and gang violence could also have a negative impact on transgender women and men because many are victims of gang violence who are targeted for being transgender."I know it will be difficult to win asylum," said Alexa Amaya, a 24-year-old from Honduras, "but we have to make the attempt."The caravan has traveled more than 1,000 miles (more than 2,000 kilometers) in the month since its initial participants set out from San Pedro Sula, Honduras, and as it traverses Mexico's central highlands it's still about the same distance from its goal of Tijuana, across the border from San Diego. It's unclear how many will make it. A similar caravan earlier this year fizzled to just about 200 who reached the U.S. frontier.Much of the trek has been on foot, but hitching rides in pickup trucks, minibuses and tractor-trailers has been crucial lately, especially on days when they travel 100 miles or more. For the LGBTQ group, it's been tougher to find those rides."A taxi driver kicked us out of his car," said Lady Perez, a 23-year-old from Honduras, adding that sometimes truck drivers who often transport migrants for a small fee have doubled or tripled the price for her group.Lady began identifying as transgender at age 5, and her father ultimately disowned her. She was subjected to insults and beatings, her boyfriend was killed and she was warned to leave Honduras or else."In our country the rights of the LGBTQ community are not respected, and anti-social groups take advantage of that," Lady said.Walking on the highway in a black miniskirt, red lipstick and black eyeliner, she said many men in the caravan have been harassing her and the others."They have denigrated us. Supposedly you're emigrating from your country because of the violence, the discrimination, the homophobia, and it turns out that in the very caravan you face this kind of violence," she said.In the face of the near-constant harassment, march organizers and human rights workers have sought to provide the group some security in the form of two men in green vests who travel with them and try to ward off any attacks.If the verbal harassment doesn't cross the line, "we feel protected," Loly said. "If someone does cross the line, human rights is with us to protect us."___Associated Press writer Astrid Galvan in Phoenix contributed to this report. 6973

MARTIN COUNTY, Florida — The Martin County Sheriff's Office said a 28-year-old man faces poaching charges after deputies said he was caught with two gopher tortoises at a state park.Deputies responded Sunday evening to Seabranch Preserve State Park and found the suspect, identified as Robert Lane, on the ground.The sheriff's office said Lane pulled two endangered tortoises from their hole and was on the ground searching for others.Lane was in possession of a male and a female gopher tortoise when deputies caught him.They said he admitted to deputies that he pulled both of the tortoises from their hole and was going to take them home where he had planned to eat them.Gopher tortoises are a threatened species and federally protected.The case was turned over to the Florida Fish and Wildlife Conservation Commission. Lane faces charges related to poaching on state property.Deputies said they found the hole where Lane pulled the tortoises from and returned both reptiles to the location.  1043

Many people across the country are full of hope now that a few COVID-19 vaccines are showing positive results, and they appear to be highly effective. But will Americans be willing to get a shot?Before Pfizer, Moderna and Astra Zeneca shared their results, Gallup Economics conducted a poll with Franklin-Templeton on what it would take for Americans to be willing to get a COVID-19 vaccine."We decided to dig deeper to why people are skeptical of a vaccine and see what pieces of information make a difference in effecting their decision in getting it or not," said Jonathan Rothwell, the Principal Economist at Gallup. Rothwell says, instead of a traditional Gallup Poll with multiple choice or open-ended questions, the more than 5,000 people surveyed were broken into groups of 200. Each group was asked different questions, proposing various scenarios and hypotheticals about a vaccine."'Imagine there's a vaccine that's going to be widely available in either', and then we varied the timing to be either the end of this year or beginning of next year. We varied whether we disclosed if it came after the FDA did three rounds of clinical trials or mention it was FDA approved," said Rothwell. People were also asked about how effective a vaccine would need to be and who would have to recommend it in order to take it."I would say the most surprising thing was telling people the Food and Drug Administration approved the vaccine after three rounds of clinical trials had a slightly negative, not significant effect relative to just telling them it's just FDA approved," said Rothwell.The results also showed African-Americans and Hispanics were more skeptical of a COVID-19 vaccine and that most people wouldn't resume activities like going to the store without a mask, traveling, or sending their kids back to school just because a COVID-19 vaccine was available.Dr. Bali Pulendran, a professor of microbiology and immunology at Stanford University, says news about the high efficacy of two different COVID-19 vaccines is extremely positive, but he understands people's hesitations."It's understandable because this is unprecedented, no one has developed vaccines at such warp speed. But, again, it has to be driven by the data and what the data shows us now is that at least in the short term, we have these vaccines that are in excess of 90% effective and safe," said Dr. Pulendran.Dr. Pulendran says just because it took less than a year to develop an effective COVID-19 vaccine, doesn't mean corners were cut to get there."The methods used to make these vaccines have gone through the same high rigorous standards that have always been used to make any number of vaccines that have been administered and that have been proven to be safe and effective. By that, I mean they’ve gone through phase one, phase two, phase three human trials, multiple independent bodies have looked at the data," said Dr. Pulendran.Gallup hopes scientists, doctors and politicians will use the results of this poll to help guide their messaging to the general public so that most people will be encouraged to get a COVID-19 vaccine when it becomes available. 3155