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The first participant in a clinical trial for a vaccine to protect against the new coronavirus will receive an experimental dose on Monday, according to a government official.The National Institutes of Health is funding the trial, which is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle. The official who disclosed plans for the first participant spoke on condition of anonymity because the move has not been publicly announced.Public health officials say it will take a year to 18 months to fully validate any potential vaccine. Testing will begin with 45 young, healthy volunteers with different doses of shots co-developed by NIH and Moderna Inc. There’s no chance participants could get infected from the shots, because they don’t contain the virus itself. The goal is purely to check that the vaccines show no worrisome side effects, setting the stage for larger tests.Dozens of research groups around the world are racing to create a vaccine as COVID-19 cases continue to grow. Importantly, they’re pursuing different types of vaccines — shots developed from new technologies that not only are faster to produce than traditional inoculations but might prove more potent. Some researchers even aim for temporary vaccines, such as shots that might guard people’s health a month or two at a time while longer-lasting protection is developed.Also in the works: Inovio Pharmaceuticals aims to begin safety tests of its vaccine candidate next month in a few dozen volunteers at the University of Pennsylvania and a testing center in Kansas City, Missouri, followed by a similar study in China and South Korea.Even if initial safety tests go well, “you’re talking about a year to a year and a half” before any vaccine could be ready for widespread use, according to Dr. Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases.That still would be a record-setting pace. But manufacturers know the wait — required because it takes additional studies of thousands of people to tell if a vaccine truly protects and does no harm — is hard for a frightened public.President Donald Trump has been pushing for swift action on a vaccine, saying in recent days that the work is “moving along very quickly” and he hopes to see a vaccine “relatively soon.”Today, there are no proven treatments. In China, scientists have been testing a combination of HIV drugs against the new coronavirus, as well as an experimental drug named remdesivir that was in development to fight Ebola. In the U.S., the University of Nebraska Medical Center also began testing remdesivir in some Americans who were found to have COVID-19 after being evacuated from a cruise ship in Japan.For most people, the new coronavirus causes only mild or moderate symptoms, such as fever and cough. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia. The worldwide outbreak has sickened more than 156,000 people and left more than 5,800 dead. The death toll in the United States is more than 50, while infections neared 3,000 across 49 states and the District of Columbia. The vast majority of people recover. According to the World Health Organization, people with mild illness recover in about two weeks, while those with more severe illness may take three weeks to six weeks to recover.___The Associated Press receives support for health and science coverage from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3597

The family of the suspect from Sunday's mass shooting in Dayton, Ohio issued a statement on Tuesday, thanking police and first responders while also asking for privacy.It was the first statement released by the family of Connor Betts, who allegedly killed nine people — including his sister — outside an entertainment district.A police officer from the Bellbrook Police Department delivered the statement on Tuesday evening.Read the family's partial statement below: 478

The House Oversight and Government Reform Committee will hold a hearing this summer on a proposal to grant statehood to Washington, DC, reportedly the first House hearing in more than 25 years on the long-shot bid to transform the federal district into the nation's 51st state.The hearing on 304

Thank u; Coachella is "next" for Ariana Grande.The pop star highlights the 2019 Coachella Valley Arts and Music Festival, which will take place near Palm Springs, California in mid-April. Grande will headline Sunday shows on April 14 and 21.Grande's performance will kick off 2019 after a wild two years — in 2017 23 people were killed at her show in Manchester, England after a terrorist detonated a bomb, and 2018 saw a whirlwind relationship with comedian Pete Davidson and the death of her ex-boyfriend, Mac Miller.Childish Gambino will headline Friday shows at Coachella on April 12 and 19. The rapper, also known as actor Donald Glover has said that his upcoming album will be his last under the "Gambino" moniker. His 2018 music video for "This Is America" received universal acclaim.Tame Impala will headline Saturday shows on April 13 and 20. Kevin Parker, who records all of the band's music solo, won a ARIA Award for best album of the year in 2015 for the band's third album, "Currents."See the full Coachella 2019 lineup in the tweet below. 1065

The legal troubles for Jeffrey Epstein, a wealthy hedge fund manager, date back to 2005 when a 14-year-old girl and her parents claimed Epstein molested her at his mansion in Palm Beach, Florida. That was the beginning of an investigation that started at a local level and ended up in the hands of the FBI.But even then, in 2008, Epstein pleaded guilty to only two prostitution charges — one for solicitation of a minor.He served 13 months in the Palm Beach County stockade, part of that out on work release, before he got out in 2009.He was required to register as a sex offender.During that time, lawsuits began pouring in: first, in 2008, from an anonymous woman seeking million, saying she was forced to have sex with Epstein when she was a teen.Epstein settled those cases out of court for an undisclosed sum.Last month he was arrested again, this time by federal agents in New York for sex trafficking charges.The FBI credited investigative reporting to their case. And as a result, numerous investigations have now been launched at the federal, state and local level.In late July Epstein was found injured in his jail cell with marks on his neck.He was placed on suicide watch following the incident.On Friday a federal appeals court unsealed nearly 2,000 pages of records related to a civil case against a victim and the woman who allegedly procured teens for Epstein. It included names of other high-profile individuals possibly tied to Epstein’s sex ring.On August 10, 1495

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