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WASHINGTON, June 16 (Xinhua) -- Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage. New research by a team of scientists at the University of Rochester has unveiled an important new mechanism that allows cells to recognize when they are under stress and prime the DNA repair machinery to respond to the threat of damage.Their findings will be published Friday in journal Science. Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage.The scientists, led by biologists Vera Gorbunova and Andrei Seluanov, focused on the most dangerous type of DNA damage -- double strand breaks. Unrepaired, this type of damage can lead to premature aging and cancer. They studied how oxidative stress affects efficiency of DNA repair. Oxidative stress occurs when the body is unable to neutralize the highly-reactive molecules, which are typically produced during routine cellular activities.The research team found that human cells undergoing oxidative stress synthesized more of a protein called SIRT6. By increasing SIRT6 levels, cells were able to stimulate their ability to repair double strand breaks. When the cells were treated with a drug that inactivated SIRT6, DNA repair came to a halt, thus confirming the role of SIRT6 in DNA repair. Gorbunova notes that the SIRT6 protein is structurally related to another protein, SIR2, which has been shown to extend lifespan in multiple model organisms."SIRT6 also affects DNA repair when there is no oxidative stress," explains Gorbunova. "It's just that the effect is magnified when the cells are challenged with even small amounts of oxidative stress."SIRT6 allows the cells to be economical with their resources, priming the repair enzymes only when there is damage that needs to be repaired. Thus SIRT6 may be a master regulator that coordinates stress and DNA repair activities, according to Gorbunova.
BEIJING, Sept. 8 (Xinhuanet) -- Middle-aged white women drinking alcohol moderately are more likely to stay healthy than nondrinkers, according to a new study from Harvard.The study has followed about 14,000 mostly white women since 1976.As a result, compared with teetotalers, those who had 3 to 15 alcoholic drinks weekly in their late 50s were 28 percent higher of being free from physical disability, chronic illness, mental health problems, and cognitive decline at the age of 70.Even having just one or two drinks per week increased a woman's odds of good health by 11 percent.However, women should be aware that even moderate drinking has been linked to an increased risk of breast cancer, said Qi Sun, M.D., a lead author of the study and a nutrition researcher at the Harvard School of Public Health.These findings don't necessarily apply to men or to nonwhite women. But they reinforced the evidence for the health benefits of moderate drinking.

BEIJING, June 12 (Xinhua) -- China's Supreme People's Court (SPC) on Sunday publicized a judicial interpretation which sets specific rules for the country's courts to order penalties to criminals sabotaging TV and radio facilities.The interpretation said that criminals, whose sabotage causes information block for disaster early warning, rescue and others concern public security, could be convicted three to seven years of imprisonment on the charge of sabotaging TV and radio broadcast facilities.Other circumstances that could be convicted the imprisonment include sabotage that causes malfunction in the broadcast of TV and radio stations, according to the new law.According to statistics with the SPC, there have been more than 5,000 cases of sabotaging cable TV wires and more than 1,000 cases of sabotaging state-owned fiber optic lines and other cases of stealing broadcast facilities since 2006 in China.
BEIJING, Sept. 4 (Xinhua) -- Officials and delegations from China and African countries have gathered at a seminar being held in Beijing to discuss rural development and economic growth.The seven-day seminar kicked off on Sunday, attracting representatives from China and 11 African countries to exchange views and experiences related to the seminar's theme of "agriculture and rural development."Justin Lin Yifu, chief economist and senior vice president of the World Bank, said at the seminar's opening ceremony that African countries should take cues from China's experience in creating a series of policies to bolster agricultural and rural development, as these policies have also facilitated the country's economic growth.Hu Jinglin, assistant to China's Minister of Finance, said improved agricultural cooperation between China and Africa will help enhance global grain security.China has worked on 142 cooperative agricultural projects with 14 African countries to date. In addition, it has sent 104 agricultural experts to 33 African countries to train more than 4,200 local agricultural technicians.
LOS ANGELES, June 29 (Xinhua) -- The war on cloud intensified as Microsoft Office announced its decision on Tuesday to go cloud in an attempt to compete with its immediate but not last competitor, Google Docs.Microsoft holds a virtual monopoly on office productivity software. Most computer users in the world use the Office software for word processing, spreadsheet, presentation and other purposes. However, Microsoft Office faces a strong enemy -- Google Docs, which provides cloud service, that means users do not have to purchase any software to be installed on their computers. If they go online, they can start use the application, and they do not need to worry about their files, because the files also go with the cloud, and users can get access to their files at anytime, anywhere.The cloud-based Office 365 is designed for the mobile age when people go with their software and documents.The actual features and functionality of the tools have a lot of bearing on which productivity suite users choose. The Word Web App is more visually appealing and polished than its Google counterpart, but overall the two seem roughly equivalent in features.When tested on a sample presentation in both the PowerPoint Web App and Google Docs Presentation, the PowerPoint Web App immediately presented with a diverse selection of attractive themes to choose from, but Google defaulted to plain black text on a plain white background.On slide and image, in Google Presentations, the image filled the whole slide but the PowerPoint Web App was smart enough to size the image automatically.When push comes to shove, the features of the Office Web Apps in Office 365 are pretty much the same as what Google Docs has to offer. However, Microsoft makes key features easier to get to, and works more intuitively. For users already familiar with Microsoft Office, the Office Web Apps version is easy to use.Both Office 365 and Google Docs are Web-based platforms, and they will work from any Web browser. Google Docs excels in the Chrome browser while Microsoft Office 365 works best in Internet Explorer. It makes sense that each would make sure that their online productivity tools are optimized for performance and functionality in their own browser.Collaboration in real time is the primary selling point of Google Docs, which can be shared with any other Google account. The users who share a file can all access and work with it simultaneously. Each user is assigned a unique color so users can easily identify who is making changes to what.But in the price war, Microsoft can not beat Google Docs. Office 365 starts at six dollars per user per month for the Professional and Small Business plan. The Medium Business and Enterprise plans range from 10 to 27 dollars per user per month. But the Google Docs is free.Microsoft also faces a challenge on how to go cloud while still keep the computer-based Office software.Statistics showed that nearly nine of every 10 office computers runs one of the 14 versions of Office the company has released since the software's launch in 1989. The company now needs to convince those computer users, estimated at about one billion, to switch to Office in the cloud without disrupting the legacy version that is financing the transition.The growing cloud market is profitable. The International Data Corp. projected the market for cloud-computing services and software is expected to grow more than 27 percent annually over the next five years and reach 73 billion dollars by 2015.It is estimated that by 2015 one of every seven dollars spent on technology will be connected with cloud computing and the winners of the cloud platform wars will likely be the new power brokers of the IT industry.It is reported that Salesforce.com has added a communication technology called Chatter to its service to allow clients to communicate within its sales management cloud service. Amazon's Elastic Cloud has attracted enterprise customers because of its ability to scale up capacity to match peaks in client demand.By 2015, it is estimated that software-oriented cloud services will account for roughly three-quarters of all spending on public cloud services. Enditem
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