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Researchers published what they say is the first case of a living person diagnosed with the degenerative brain disease chronic traumatic encephalopathy or CTE.While unnamed in the study, lead author Dr. Bennet Omalu confirmed to CNN that the subject of the case was former NFL player Fred McNeill -- who died in 2015.Omalu is credited with first discovering CTE in professional football players. Until now, the only way to diagnose the disease is with a brain exam after death.The diagnosis was first made using an experimental brain scan that can trace a signature protein of CTE called tau. The authors then confirmed the diagnosis with an autopsy. The case study was published in the journal Neurosurgery this week.'It looked like just depression'Omalu first presented these findings exclusively to CNN's chief medical correspondent, Dr. Sanjay Gupta, in 2016. McNeill's wife, Tia, and his two sons, Gavin and Fred Jr., told Gupta then that they saw Fred transform from a fun loving family man at the center of their lives into a man who was dealing with symptoms of memory loss, anger and depression that tore their family apart."There are some times where the father is the stronghold in the family, or the anchor. If you lose that, everything kind of falls apart. That's kind of what happened for us. It looked like financial issues at first; it looked like marital issues, and they separated; then it looked like just depression," Gavin told Gupta.CTE is known for plaguing people with Alzheimer's like symptoms such as memory loss, rage, mood swings, and in some cases, suicidal ideation.Severity of the disease is categorized into four stages, with stage 4 being the most severe. While researchers don't know exactly why certain people develop the disease and others don't, they believe that it results from repeated blows to the head that trigger a build up of tau proteins in the brain.CTE has been called football's "concussion crisis," however experts point out that CTE can develop from any repeated head injury. According to the Boston University CTE Center, "this trauma includes both concussions that cause symptoms and subconcussive hits to the head that cause no symptoms." These subconcussive hits can include the repeated trauma the brain experiences from constant plays, hitting the turf, and tackling. Wrestlers, boxers, and military troops have also been diagnosed with the disease.Seeing CTEWhile McNeill is the first case to be confirmed with an autopsy, the experimental technology has been used on at least a dozen other former NFL players, including Pro Football Hall of Famer, Dallas Cowboy Tony Dorsett. Omalu helped develop and is invested in the diagnostic exam, which uses a radioactive "tracer" called FDDNP to bind to tau proteins in the brain. The tau proteins can then be seen on a PET scan of the brain.Critics have said the protein also can highlight another protein called amyloid, which may be indicative of Alzheimer's or other forms of dementia. But Omalu noted that in CTE, tau makes distinctive patterns in the brain. It has a "specific topographic signature," he said, and that pattern can be detected in imaging.Omalu said he and his team are currently raising money to start a phase 3 clinical trial to further test the technology and replicate what they have seen in McNeill. He anticipates that once funds are raised, it will take another two to three years for the trial and then another year, at least, for approval from the US Food and Drug Administration. When asked, how soon a commercial test could be available, Omalu predicted it could be as soon as a few years. "We are looking at less than five years," he said.  3711

President Donald Trump's attorney-turned-enemy Michael Cohen is launching a podcast Monday, titled “Mea Culpa." He tells The Associated Press his first guest will be comedian and talk-show host Rosie O'Donnell. Once at odds, Cohen says he and O'Donnell have become friends and bonded as a result of the grudge they bear toward Trump. “First episode. First interview. First feud. First family,” Cohen told The Associated Press by phone late Thursday.Trump and O’Donnell have engaged in a lengthy public feud. Challenged during a presidential primary debate in 2015 about how he described some women as “fat pigs,” “dogs” and “slobs,” Trump responded by saying: “Only Rosie O’Donnell.”Cohen says his relationship with O'Donnell began while he was imprisoned for tax crimes, lying to congress and campaign finance violations. He says O'Donnell sent him a six-page letter. Cohen wrote an apology in response, which prompted O'Donnell to visit him in prison. 961

President Trump's senior adviser and son-in-law Jared Kushner told journalist Bob Woodward during a taped interview in mid-April that Trump was "getting the country back from the doctors" amid the coronavirus pandemic.According to newly released audio obtained by CNN, Kushner's comment came as more than 40,000 people in the U.S. had already died from COVID-19. 370

President Donald Trump tweeted a photo on Wednesday of rockets that were aimed at the US Embassy in Baghdad, and claimed that the rockets were fired by Iran.The attack came on Sunday, embassy officials confirmed. Trump said that three of the rockets failed to launch.The embassy said that there was minor damage to the compound, but no injuries. The US embassy said there were reports of damage and injuries in residential communities near the embassy.“These sorts of attacks on diplomatic facilities are a violation of international law and are a direct assault on the sovereignty of the Iraqi government,” the US Embassy in Baghdad tweeted.“Some friendly health advice to Iran: If one American is killed, I will hold Iran responsible. Think it over,” Trump said on Wednesday.Tensions rose earlier this year between Iran and the US after Iranian General Qasem Soleimani was killed after a US attack on the influential Iranian military leader. Iran responded by firing more than a dozen missiles that struck two airbases in Iraq that houses U.S. troops, the Pentagon confirmed. Iran said at the time that it did not seek to escalate tensions between the two nations."Iran took & concluded proportionate measures in self-defense under Article 51 of UN Charter targeting base from which cowardly armed attack against our citizens & senior officials were launched," Iran's Foreign Minister Javad Zarif said in January. "We do not seek escalation or war, but will defend ourselves against any aggression."Saeed Khatibzadeh, a spokesperson for Iran’s foreign ministry, alleged on Monday that the US was responsible for escalating tensions following Sunday’s attack.“We strongly refute Secretary (Mike) Pompeo 's irresponsible anti-Iran accusations, which blatantly aim to create tension,” Khatibzadeh tweeted. “Iran rejects any attack on diplomatic missions. The U.S. military presence is the source of instability in our region. No amount of spin can divert blame for its evils.” 1991

Race favorite Justify, ridden by Mike Smith, won the 144th Kentucky Derby on a sloppy track at Louisville's Churchill Downs on Saturday.Justify is trained by Bob Baffert, who now has five Derby wins.Good Magic finished second, just ahead of Audible. The winning time was 2:04.20.Justify, the 5-2 favorite, became the first Derby winner in 136 years that did not race as a 2-year-old. The chestnut colt has won all four starts as a 3-year-old. 450

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