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LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).

WASHINGTON, July 20 (Xinhua) -- Using the Hubble Space Telescope, astronomers have discovered a fourth moon orbiting the icy dwarf planet Pluto, the U.S. National Aeronautics and Space Administration (NASA) announced Wednesday in a statement. The tiny, new satellite, temporarily designated P4, was uncovered in a Hubble survey searching for rings around the dwarf planet.P4 was first seen in a photo taken with Hubble's Wide Field Camera 3 on June 28. It was confirmed in subsequent Hubble pictures taken on July 3 and July 18. It is the smallest moon discovered around Pluto. It has an estimated diameter of 8 to 21 miles (13 to 34 km). By comparison, Charon, Pluto's largest moon, is 648 miles (1,043 km) across, and the other moons, Nix and Hydra, are in the range of 20 to 70 miles in diameter (32 to 113 km).Two labeled images of the Pluto system taken by the Hubble Space Telescope's Wide Field Camera 3 ultraviolet visible instrument with newly discovered fourth moon P4 circled. The image on the left was taken on June 28, 2011. The image of the right was taken on July 3, 2011."I find it remarkable that Hubble's cameras enabled us to see such a tiny object so clearly from a distance of more than 3 billion miles (5 billion km)," said Mark Showalter of the SETI Institute in California, who led this observing program with Hubble.P4 is located between the orbits of Nix and Hydra, which Hubble discovered in 2005. Charon was discovered in 1978 at the U.S. Naval Observatory and first resolved using Hubble in 1990 as a separate body from Pluto.The dwarf planet's entire moon system is believed to have formed by a collision between Pluto and another planet-sized body early in the history of the solar system. The smashup flung material that coalesced into the family of satellites observed around Pluto.The finding is a result of ongoing work to support NASA's New Horizons mission, scheduled to fly through the Pluto system in 2015. The mission is designed to provide new insights about worlds at the edge of our solar system. Hubble's mapping of Pluto's surface and discovery of its satellites have been invaluable to planning for New Horizons' close encounter."This is a fantastic discovery," said New Horizons' principal investigator Alan Stern of the Southwest Research Institute in Colorado. "Now that we know there's another moon in the Pluto system, we can plan close-up observations of it during our flyby."

CHENGDU, Sept. 20 (Xinhua) -- A United Nations official said Tuesday that she hopes China will take every opportunity to reinforce, support and lead the UN's agenda and "infuse it with strength and wisdom.""The more China gives, the better the UN can become," said Renata Lok-Dessallien, UN Resident Coordinator and United Nations Development Program (UNDP) Resident Representative in China, at the Seminar in Memory of the 40th Anniversary of the Resumption of Lawful Rights of China in the United Nations.The three-day seminar from Sept. 19 to 21 is being held in the city of Chengdu in southwest China's Sichuan Province. About 100 UN and Chinese officials are gathering to discuss China's role in the UN, as well as the UN's role in global diplomacy.Lok-Dessallien said that the General Assembly Resolution of Oct. 25, 1971 was an "important milestone in China's international relations and in the history of the United Nations.""It restored the rights of the People's Republic of China in the United Nations and marked China's entry to the world stage," she said.Steven Sabey, a senior policy advisor from the UNDP's China office, said that China plays an important role in facilitating cooperation about the member states of the United Nations."China needs the United Nations, and the United Nations also needs China," said Wu Hailong, China's assistant minister of foreign affairs."We must recognize that as the largest developing country in the world, China needs to manage its domestic affairs first, as this can have a positive effect on humanity as a whole," Wu said.As China's role in the world continues to grow and evolve, the UN's role in China will also grow, according to Lok-Dessallien."As China's development trajectory continues to evolve, we are entering significantly new territory in the UN-China relationship," she said.Sabey said that he hopes China will strengthen its cooperation with the United Nations in order to further improve intercultural communication and allow China to contribute more to other developing countries."The United Nations is committed to continuing to deepen and strengthen our partnership as we tackle the many global challenges ahead," said Lok-Dessallien.

LOS ANGELES, June 8 (Xinhua) -- NASA's Mars Exploration Rover Opportunity is heading toward "Spirit Point" on the rim of a large crater, a long-term destination that the rover has been trying to reach for nearly three years, the Jet Propulsion Laboratory (JPL) announced on Wednesday.Opportunity has moved toward the crater, Endeavour, since climbing out of Victoria crater in August 2008.Having driven 11 miles (18 kilometers), the rover has about two miles (about three kilometers) to go before reaching the rim of Endeavour, said JPL in Pasadena, Los Angeles.Rover team members last week selected "Spirit Point" as the informal name for the site on the rim where Opportunity will arrive at Endeavour crater. The choice commemorates Opportunity's rover twin, Spirit, which has ended communication and finished its mission."Spirit achieved far more than we ever could have hoped when we designed her," said Steve Squyres of Cornell University, Ithaca, New York, principal investigator for the rovers. "This name will be a reminder that we need to keep pushing as hard as we can to make new discoveries with Opportunity. The exploration of Spirit Point is the next major goal for us to strive for."Endeavour offers the setting for plenty of productive work by Opportunity. The crater is 14 miles (22 kilometers) in diameter -- more than 20 times wider than Victoria crater, which Opportunity examined for two years. Orbital observations indicate that the ridges along its western rim expose rock outcrops older than any Opportunity has seen so far. Spirit Point is at the southern tip of one of those ridges, "Cape York," on the western side of Endeavour.Opportunity and Spirit completed their three-month prime missions on Mars in April 2004. Both rovers continued for years of bonus, extended missions. Both have made important discoveries about wet environments on ancient Mars that may have been favorable for supporting microbial life.NASA's JPL, a division of the California Institute of Technology in Pasadena, manages the Mars Exploration Rover Project for the NASA Science Mission Directorate, Washington.

BEIJING, Sept. 20 (Xinhuanet)-- Google's executive chairman Eric Schmidt is to face a Senate hearing on whether the company is abusing its dominance in Internet search, according to media reports on Tuesday.At the Wednesday's hearing before the Senate Judiciary Committee's antitrust panel, Schmidt will argue that critics are wrong to say Google gives preference to its own products, instead, Google is just trying to deliver the best-cultivated search results for users. The issue of search ranking is a touchy subject with Google, which says its algorithm is devised to give users the most useful result so they will come back.Another focal point of the hearing, which Schmidt concerned most is "scrapers", those who game its search algorithm, for example, taking commonly searched words, combine them into a nonsensical block of text and throw it up on the Web to grab eyeballs and advertising dollars.Google believes that, if scrapers succeed too often, consumers will lose confidence in search and turn to other resources, thus posing an existential threat to the company.Regulators in the U.S. and abroad have been looking into various aspects of Google's business practices since the company's 2007 purchase of ad firm DoubleClick. At the moment, European regulators are conducting an antitrust inquiry into Google's search business while the Federal Trade Commission is doing likewise. Google relies overwhelmingly on its core product, Internet search, and dominates the market for that product. It handles around two-thirds of U.S. Internet searches and more than 80 percent in many European countries, according to comScore Inc.