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SAN DIEGO (KGTV) – A year-long construction project to improve State Route 163 hit a milestone Tuesday morning with the completion of work on Friars and Frazee Roads.Crews arrived early in the morning, finishing up last minute preps before the big reveal. One noticeably new addition are signal lights put in place to help regulate the flow of traffic.The city also made improvements, like adding lanes on Friars Road. There are four lanes going east and four lanes going west. Changes to the on and off ramps from the 163 onto Friars Road may reduce the confusion and congestion caused by the old traffic pattern. Crews also added sidewalks and clearly-marked bike lanes. “We can separate and have a path for all modes of traffic including foot and bike traffic. So, it will be safer for everyone using Friars Road. It’s a safer facility now that we made these improvements," said a Caltrans spokesperson.The “Open for Business,” ceremony took place at 10 a.m. 969

SAN DIEGO (KGTV) — An hours-long standoff between San Diego Police and a burglary suspect ended late Thursday night in the Marina area.The standoff, which started at about 4:30 p.m., occurred in the area of West Harbor Dr., between Kettner Blvd. and Pacific Highway. Police called Emergency Negotiation Team and SWAT officers, and a Psychiatric Emergency Response Team to the scene. Shortly after 11 p.m., SDPD said the San Diego Police suspect had been taken into custody.No further information was immediately available. 530

SAN DIEGO (KGTV) -- A woman died after crashing into a tree in Mira Mesa Sunday morning. According to California Highway Patrol, the woman was driving north on I-15 when she veered off the road, striking a tree and a light pole near Carroll Canyon Road around 1:18 a.m. The woman died at the scene, according to CHP. The agency says a man was riding in the passenger seat at the time of the crash. He was taken to the hospital with unknown injuries. At this time, it’s unknown if drugs or alcohol may been involved. 524

SAN DIEGO (KGTV) — A small San Diego biotech is trying to give face masks an added layer of defense by spraying the liner with a biological bait designed to be a mousetrap for the coronavirus.AXIM Biotechnologies is also developing a next-generation rapid antibody test that the company says is the first of its kind to detect “neutralizing antibodies.” The neutralizing antibody test should be available for sale in the next few weeks, said CEO John Huemoeller.Both the test and the surgical mask are based on the same technology: a synthetic protein AXIM created that mimics ACE2.ACE2 is a receptor protein found in your body on the surface of cells. The coronavirus likes to bind to it to infiltrate cells, so the company decided to coat the inner lining of a surgical mask with the protein as an added barrier.“They lock to each other just like they do in your body. They lock on the mask. So when we spray the mask with that virus-binding protein, it's there permanently. It can be washed. It's not coming off,” Huemoeller said.“That's the whole idea is to get [the virus] to bind to something, so it cannot go into your respiratory system,” he added.AXIM’s mask is still a ways off from hitting the market. Huemoeller said it needs to undergo further testing to get FDA approval and the company is still looking for a manufacturing partner. The company is hoping to release the enhanced mask by the middle of next year.“We’re hoping that maybe [the FDA will] steamline it because this is something that can save lives,” Huemoeller said.With fewer than 10 scientists, AXIM is a small biotech based in Sorrento Valley. But the company thinks it's poised to be at the center of the second wave of antibody tests for so-called neutralizing antibodies.“When the FDA got our application they didn't know what neutralizing antibodies were. And now everybody's talking about neutralizing antibodies,” said Huemoeller.Not all antibodies function the same. Some antibodies bind to the virus but still allow the pathogen to infiltrate cells. Other antibodies, called neutralizing antibodies, bind to the virus and actually prevent further infection.AXIM’s lateral flow assay antibody test, dubbed Tru-19, takes a drop of blood and can return results in 10 minutes to determine if someone has neutralizing antibodies, according to Huemoeller.In addition to uses at doctors’ offices, the company said the test would have immediate applications at labs processing convalescent plasma.Since as many as one-third of people who recover from COVID-19 do not produce neutralizing antibodies, Huemoeller said the test could help determine which patients would be optimal candidates to donate plasma. 2693

SAN DIEGO (KGTV) - An early morning collision involving a tractor-trailer stopped traffic near Mission Valley Saturday.The big rig crash on northbound Interstate 15 near the I-8 connector blocked all lanes, creating a complete standstill of the morning commute.Traffic was being diverted onto I-8, however, all lanes reopened just before 6 a.m. It's not clear how the collision occurred.TRAFFIC MAP: FIND A NEW ROUTEIt's not clear if anyone was seriously injured in the crash.10News is monitoring this breaking news story. 530