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2025-06-02 17:53:42
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  宜宾双眼皮吸脂   

There are thousands of suitcases in Ocean City over the summer, but police found one packed with something unusual on Tuesday. According to Lt. Schreier of the Worcester County Sherriff’s office, a couple stumbled over a trunk in the water in West Ocean City at Homer Gudelsky Park. Inside they found personal objects like shoes and pottery as well as one or two bones. Maryland State Police, Maryland Natural Resources Police and the Worcester County Sheriff's Office are on the beach investigating, and a dive team was trying to pull the trunk from the water in hopes of reserving anything that could be evidence.  664

  宜宾双眼皮吸脂   

Theater chain AMC says it could run out of money by the end of the year, according to multiple reports.AMC Theatres said Tuesday that its existing cash resources would be "largely depleted" by the end of this year or early next year because of the "reduced movie slate for the fourth quarter," as well as "the absence of significant increases in attendance from current levels."The company says they either need to sell more tickets or find new ways to borrow money.AMC has about 500 of their 600 American theaters open at between 20-40 percent capacity depending on local regulations to stop the spread of the coronavirus.Cineworld Group, which owns Regal Cinemas, announced last week it would suspend operations at all theaters in the US and UK.Meanwhile, the film industry has pushed release dates or gone straight to streaming platforms as the pandemic continues to disrupt theater attendance and filming schedules.Marvel’s “Black Widow” and the latest James Bond film “No Time to Die” were pushed to 2021. Pixar’s “Soul” will not appear in theaters and will go straight to Disney+, like Disney’s live-action remake of “Mulan.”There are only a few new films still slated for a 2020 release, including Universal’s “The Croods: A New Age,” Disney’s “Free Guy,” Paramount Pictures’ “Coming 2 America” and Warner Bros.′ “Wonder Woman 1984.” 1348

  宜宾双眼皮吸脂   

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676

  

THORNTON, Colo. – Police have arrested the suspect in a deadly shooting at a Thornton Walmart store.Scott Ostrem, 47, was taken into custody Thursday morning at 72nd and Federal.Witnesses told Thornton Police that Ostrem "nonchalantly" walked into the store Wednesday night, took out a handgun and began firing randomly at people. Two men and a woman were killed."This is a very heinous act," Avila said. "We don't know exactly what the motive of the person was, but it was certainly a terrible act."IMAGES | Photos capture chaotic scene after Thornton Walmart shootingPolice originally reported "multiple parties are down" after they were called around 6 p.m. to the store located at 9901 Grant Street in Thornton. The store was evacuated as authorities arrived on scene.Police found the victims in the south entrance. The two men were pronounced dead at the scene. The female victim was transported to Denver Health where she later succumbed to her injuries. Authorities have yet to identify the victims.No other physical injuries were reported. However, police say several people received medical attention for anxiety. Several distraught employees could be seen in the parking lot comforting each other.Investigators say there is no indication that terrorism was a motive, but have not ruled anything out at this point. They are still interviewing hundreds of witnesses and going through surveillance video.Special agents with the Bureau of Alcohol, Tobacco, Firearms and Explosives were helping police in the investigation.The shooting at the busy shopping center forced customers to either hide in the store or frantically run for the doors.Witness Harold Stevens said he was in the store with his son when he heard at least three shots. He said an employee directed him and his son to a back door where they were able to escape safely. 1890

  

There is no price on peace of mind when it comes to protecting your home.But there are a few things you can do to make your property safer for less than .One of the best ways is to put a deadbolt on a side door. Locksmith Jim Lang says that's one fo the first parts of a home burglars try to break into."They don't want to go through the front door and have everyone in the neighborhood see them," he said. Lang said thieves can use a credit card to pry open a door with a basic lock, but a deadbolt costs . He also spends an extra for three-inch nails to make the door stronger, so burglars can't kick it down. Lang also suggested pins to lock sliding glass doors, and a window lock to keep burglars from opening vented windows.La Mesa Police Sgt. Katy Lynch said it's also important to keep the area your front door visible. A peep-hole to see out the door should cost about . The La Mesa police has a free crime prevention program, in which officers will walkthrough homes?giving advice on how to better protect them.  Chula Vista PD does not, but a spokesman says officers attend neighborhood watch and community meetings. 10News has reached out to San Diego Police and the Sheriffs' Department. We will update this story when we hear back.  1310

来源:资阳报

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