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2025-05-28 06:21:35
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  宜宾眼睛修复手术   

SAN DIEGO (KGTV) - The La Boheme complex in the heart of North Park offers plenty of amenities. It even has a salon and Pilates studio at street level. "Pretty sure the rent's pretty up there," said Arthur Reynoso, walking by the building on Thursday. What most people don't know, however, is that 45 of the 224 condos in the building are affordable - to own. It's rare for one to come on the market, but a handful do each year. In fact, one is about to sell for 5,341, which is about 40 percent off the median condo price of 6,000 in North Park. RELATED: Making It In San Diego: How housing got so expensive"They get snapped up very quickly," said Sujata Raman, director of housing finance at the San Diego Housing Commission. The commission oversees about 250 for-sale affordable homes in San Diego - located in Carmel Valley, Black Mountain Ranch and North Park. Only four are for sale now, and Raman said all have been matched with buyers. However, they can list anytime. RELATED: Making it in San Diego: Key saving steps helped renter buy her first home"When a homeowner decides to sell we assist them by finding buyers because they ultimately have to be income approved and qualified by the housing commission," Raman said. A homeowner can sell the property to anyone he or she wishes - so long as they are qualified - but the commission still maintains an interest list and is accepting applicants. Currently, there are about 275 households qualified for that list. The homes are not listed on the MLS. Still, there are restrictions when owning one of these units. Owners must live in them, and cannot rent out any part to supplement income. The commission checks that annually. Qualified buyers usually have 60 to 110 percent of area median income. RELATED: Making It in San Diego: Best and worst places in San Diego County for home resaleBuyers must come up with a 3 percent down payment to qualify. The homes are deed-restricted for generally 45-50 years, meaning they have to be sold at an affordable price for that time span. However, once that time expires, that home becomes market rate and can be sold for any price. It doesn't reset once a property changes hands. 2194

  宜宾眼睛修复手术   

SAN DIEGO (KGTV) - The driver of an SUV involved in an apparent road rage incident in Oceanside that resulted in his vehicle ending up on its side appeared in court Friday. 180

  宜宾眼睛修复手术   

SAN DIEGO (KGTV) — The cities of Escondido and La Mesa are taking measures to help restaurants expand outdoor dining after a rollback of indoor dining in the county due to surging coronavirus cases.Starting Friday, Escondido will reduce traffic to one lane in each direction on Grand Avenue, between Maple Street and Juniper St., to allow restaurants to expand temporary outdoor seating. One lane will be reserved for parking.The city says it's also making other moves to help restaurants, including:Providing temporary barriers to restaurants for safety;Downtown Business Association has committed ,000 for shade coverings, tables, and chairs to support this effort, streamlined permitting processes for restaurants, and will reimburse businesses the 0 Alcohol Beverage Control permit fee to allow them to serve alcohol outside;City is working on the Business Recovery Temporary Use Permit for Escondido businesses.RELATED:San Diego restaurants expand to parking lots and sidewalks to stay afloatMayor Faulconer, other local leaders take action to keep restaurants openIn La Mesa, an executive order was issued Thursday to temporarily allow the use of public and private outdoor areas by restaurants for dining, with approval of the city's Director of Community Development.The city says it's also not charging fees or requiring permits for businesses that have permission to use public and private outdoor areas for dining.The moves come after indoor dining was suspended this week at restaurants throughout San Diego County, after the county was placed on California's County Monitoring List due to surging coronavirus cases. 1642

  

SAN DIEGO (KGTV) - The attorney for Rebecca Zahau’s family spoke Friday about the San Diego County Sheriff Department’s new review of her death at the Spreckels Mansion in Coronado.Earlier in the day, Sheriff Bill Gore announced that investigators found no evidence that she “died at the hands of another”. The department will not reopen the case.Zahau’s body was found hanging a the Spreckels Mansion in Coronado in 2011. Her wrists and feet were bound. For years, there has been speculation about the nature of her death, which was originally determined to be a suicide.Zahau family attorney Keith Greer suggested Friday afternoon that the Sheriff’s investigators are corrupt. “It’s not a logical decision. There’s something here that’s motivating these folks to do the wrong thing,” he told 10News. “I don’t know how they look at themselves in the mirror,” he added. Greer said that a rational person would not look at the evidence and believe that Zahau’s death was a suicide. The Zahau family lives in Missouri and did not want to be involved in Friday’s briefing at the Sheriff’s Department. They did release a recent photo of Zahau’s gravesite, surrounded by snow and flowers.Greer said he and the family are disappointed in the Sheriff’s Department, especially after a jury recently ruled in the family’s favor during the civil case. The Zahaus plan to fight the Shacknai family in their request to have the civil verdict reversed and request a new trial. 1471

  

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

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