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WASHINGTON, Dec. 7 (Xinhua) -- The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent destruction of cancer cells already resistant to commonly used chemotherapy agents, say researchers at Mayo Clinic in Florida.Their report, published on-line Wednesday in Gynecologic Oncology, suggests that this combination, ixabepilone and sunitinib, might offer a much needed treatment option for women with advanced ovarian cancer.Neither drug is approved for use in ovarian cancer. Ixabepilone is a chemotherapy drug that, like other taxane drugs, targets the microtubules and stops dividing cells from forming a spindle. It has been approved for use in metastatic breast cancer. Sunitinib, approved for use in kidney cancer, belongs to a class of tyrosine kinase inhibitors that stops growth signals from reaching inside cancer cells.When caught at late stages, ovarian cancer is often fatal because it progressively stops responding to the chemotherapy drugs used to treat it."Women die from ovarian cancer because their tumors become resistant to chemotherapy, so a drug that might be able to reduce that resistance -- which may be what this combination of agents is doing -- would be a boon to treatment of this difficult cancer," says study coauthor Gerardo Colon-Otero.The finding also highlights the importance of the role of a molecule, RhoB, that the researchers say is activated by the drug duo. It might be a potential biomarker that may help identify patients who might benefit from such combination therapy, the researchers say.

BEIJING, Sept. 29 (Xinhuanet) -- Even a slightly high blood pressure is considered dangerous to largely increase the stroke risk, a new study found.The finding was published Wednesday on the online edition of U.S. medical journal Neurology.In the study, researchers found people who have pre-hypertension, whose blood pressure measured between normal and high, are 55 percent more likely to suffer a stroke compared with normal people.The study involved data from 12 previous studies on blood pressure and stroke occurrence of some 500,000 adults.About one in three U.S. adults suffer from pre-hypertension, which is defined at a systolic blood pressure between 120 and 139 or a diastolic blood pressure between 80 and 89, according to the U.S. Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure."People who do fall into the higher range of pre-hypertension should modify their lifestyle as much as possible," suggested Dr. Bruce Ovbiagele, director of the Olive View-UCLA Stroke Program and leading author of the study.Stroke is the number three cause of death, killing more than 130,000 in the U.S. a year, according to a CBS report.

BEIJING, Dec. 14 (Xinhua) -- Chinese President Hu Jintao on Wednesday exchanged congratulatory messages with Cypriot President Demetris Christofias on the 40th anniversary of bilateral diplomatic ties.In his message, Hu said bilateral ties between China and Cyprus have developed smoothly since they were established.Political mutual trust has continued to deepen and the two countries understand each other and support each other's major concerns, he said, adding bilateral pragmatic cooperation has also been expanding continuously.China highly values its relations with Cyprus and is ready to work with the country to deepen their traditional friendship, strengthen exchanges at various levels and enhance cooperation in such areas as economy, trade, culture and tourism, the Chinese president said.Hu said China is also willing to maintain communication and coordination with Cyprus on international and regional affairs.Christofias, for his part, said China and Cyprus have carried out close exchanges and cooperation, adding bilateral ties have been further strengthened through frequent high-level exchanges in recent years.Cyprus believes the two countries are on friendly terms and understand each other, which is in line with the common interests of both China and Cyprus, Christofias said.The president said Cyprus also believes bilateral relations would make further progress in the future.Chinese Foreign Minister Yang Jiechi also exchanged congratulatory messages on Wednesday with his Cypriot counterpart Erato Kozakou Marcoullis.

BEIJING, Jan. 8 (Xinhua) -- China's central authorities have highlighted travel safety as the nation on Sunday officially kicked off the world's largest holiday migration, a time in which mass numbers of passengers will be homeward bound for the traditional Chinese Spring Festival.Safe travel has emerged as a hot-button issue facing the government as passenger trips during the 40-day travel peak are expected to hit a record high of over 3 billion.Liu Tienan, vice chief of the National Development and Reform Commission, the country's top economic planner, told the press on Sunday that passenger transport during the period is not looking good as the enormous migration outweighs existing transportation capacities.?A volunteer guides passengers to their train at Chengdu Railway Station in Chengdu, capital of southwest China's Sichuan Province, Jan. 7, 2012. Starting from Jan. 8, 2012, China's transport system will undergo a 40-day travel rush, which is characterized by a hightened passenger flow around the time of the oncoming Chinese New Year.Liu warned of the likelihood of heavy snow and icy rain that could hamper travel while vowing greater efforts to avoid another travel disaster, as was seen in early 2008 when unprecedented heavy snow and freezing rain inundated the south of the country, bringing traffic to a standstill during the peak holiday season.A total of 3.16 billion passenger trips are expected during the next 40 days, up 9.1 percent from a year earlier, of which, 235 million trips will be made via the country's railways, up 6.1 percent year-on-year.Hu Yadong, vice minister of railways, said a daily average of 5.88 million people will make train trips during the period, 340,000 more than the corresponding period in 2011.At the Beijing Railway Station on Sunday, staff members checked passengers' train tickets and ID cards, as an ID-based train ticket purchasing system kicked off nationwide at the start of the new year in an effort to curb ticket scalping.

BEIJING, Dec. 12 (Xinhua) -- A Foreign Ministry spokesman said on Monday that China welcomes the EU's new measures for coping with the European sovereign debt crisis worked out at the recently-concluded EU summit."We hope relevant measures can help stabilize the market, boost confidence in the market, stop the crisis from worsening, promote employment and economic growth, and push forward European integration," Foreign Ministry Spokesman Liu Weimin said at a routine press briefing.Last Friday at the summit in Brussels, EU leaders agreed on establishing a new "fiscal compact" based on inter-governmental treaties rather than the expected EU treaty changes. Britain opted out of the compact.Under the fiscal compact, member states will have to submit their draft budgetary plans to the European Commission, the EU's executive arm.As world's largest economy, the stable and healthy growth of the European Union and the Eurozone will be crucial to maintaining the momentum of recovery in the world economy, Liu said.China will maintain its support for EU integration, and continue to back the EU's efforts in combating the debt crisis in various ways, so as to jointly promote the stability of the international financial market and the recovery and growth of the world economy, he said."We are confident in Europe and the Eurozone, and believe that the EU has the ability and wisdom to resolve the sovereign debt crisis," Liu said.