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A Utah company is recalling two-pound frozen bags of Quest beef cat food sold nationwide over fears it may be contaminated with salmonella."Salmonella can affect animals eating the products and there is risk to humans from handling contaminated pet products, especially if they have not thoroughly washed their hands after having contact with the products or any surfaces exposed to these products," the US 419

A shop selling President Donald Trump-themed merchandise in a strip mall in suburban Philadelphia has emerged as a magnet for the president’s backers and a reflection of Pennsylvania’s status as a political battleground this year. The Trump Store in Bensalem sells hats, T-shirts, mugs, water bottles and even an inflatable Trump-shaped innertube. On a recent weekday afternoon, it did steady business over about three hours, with two to three customers continually streaming in and out. Bensalem, in Bucks County, voted for the Democrat in the last two presidential elections despite Republicans’ cutting into Democrats’ margins. Trump won Pennsylvania over Hillary Clinton by less than 1 percentage point in 2012.Photo caption: In this Thursday, Feb. 13, 2020, photo, a man walks to The Trump Store in Bensalem, Pa. The shop selling President Donald Trump-themed merchandise in a strip mall in suburban Philadelphia has emerged as a magnet for the president’s backers and a reflection of Pennsylvania’s status as a political battleground this year. (AP Photo/Matt Slocum) 1085

After losing an hour of executive time to "springing forward" his clock an hour over the weekend, President Donald Trump voiced his support Monday to eliminate states' legal requirement of "falling back" an hour each year."Making Daylight Saving Time permanent is O.K. with me!" Trump tweeted. 305

A pinch in the leg, a squeal and a trickle of tears. One baby after another in Malawi is getting the first and only vaccine against malaria, one of history’s deadliest and most stubborn of diseases.The southern African nation is rolling out the shots in an unusual pilot program along with Kenya and Ghana. Unlike established vaccines that offer near-complete protection, this new one is only about 40% effective. But experts say it’s worth a try as progress against malaria stalls: Resistance to treatment is growing and the global drop in cases has leveled off. With the vaccine, the hope is to help small children through the most dangerous period of their lives. Spread by mosquito bites, malaria kills more than 400,000 people every year, two-thirds of them under 5 and most in Africa.Seven-month-old Charity Nangware received a shot on a rainy December day at a health clinic in the town of Migowi. She watched curiously as the needle slid into her thigh, then twisted up her face with a howl.“I’m very excited about this,” said her mother, Esther Gonjani, who herself gets malaria’s aches, chills and fever at least once a year and loses a week of field work when one of her children is ill. “They explained it wasn’t perfect, but I feel secure it will relieve the pain.”There is little escaping malaria -- “malungo” in the local Chichewa language -- especially during the five-month rainy season. Stagnant puddles, where mosquitoes breed, surround the homes of brick and thatch and line the dirt roads through tea plantations or fields of maize and sugar cane. In the village of Tomali, the nearest health clinic is a two-hour bike ride away. The longer it takes to get care, the more dangerous malaria can be. Teams from the clinic offer basic medical care during visits once or twice a month, bringing the malaria shot and other vaccines in portable coolers. Treating malaria takes up a good portion of their time during the rainy season, according to Daisy Chikonde, a local health worker.“If this vaccine works, it will reduce the burden,” she said.Resident Doriga Ephrem proudly said her 5-month-old daughter, Grace, didn’t cry when she got the malaria shot.When she heard about the vaccine, Ephrem said her first thought was “protection is here.” Health workers explained, however, that the vaccine is not meant to replace antimalarial drugs or the insecticide-treated bed net she unfolds every night as the sun sets and mosquitoes rise from the shadows. “We even take our evening meals inside the net to avoid mosquitoes,” she said.It took three decades of research to develop the new vaccine, which works against the most common and deadly of the five parasite species that cause malaria. The parasite’s complex life cycle is a huge challenge. It changes forms in different stages of infection and is far harder to target than germs.“We don’t have any vaccines against parasites in routine use. This is uncharted territory,” said Ashley Birkett, who directs PATH’s Malaria Vaccine Initiative, a nonprofit that helped drugmaker GlaxoSmithKline develop the shot, brand-named Mosquirix. The bite of an infected mosquito sends immature parasites called sporozoites into the bloodstream. If they reach the liver, they’ll mature and multiply before spewing back into the blood to cause malaria’s debilitating symptoms. At that point, treatment requires medicines that kill the parasites.Mosquirix uses a piece of the parasite — a protein found only on sporozoites’ surface — in hopes of blocking the liver stage of infection. When a vaccinated child is bitten, the immune system should recognize the parasite and start making antibodies against it.Scientists also are searching for next-generation alternatives. In the pipeline is an experimental vaccine made of whole malaria parasites dissected from mosquitoes’ salivary glands but weakened so they won’t make people sick. Sanaria Inc. has been testing its vaccine in adults, and is planning a large, late-stage study in Equatorial Guinea’s Bioko Island.And the U.S. National Institutes of Health soon will start initial tests of whether injecting people periodically with lab-made antibodies, rather than depending on the immune system to make them, could offer temporary protection during malaria season. Think of them as “potentially short-term vaccines,” NIH’s Dr. Robert Seder told a recent meeting of the American Society of Tropical Medicine and Hygiene.For now, only babies in parts of Malawi, Kenya and Ghana are eligible for the Mosquirix vaccine. After the vaccine was approved in 2015, the World Health Organization said it first wanted a pilot roll-out to see how well it worked in a few countries — in real-world conditions — before recommending that the vaccine be given more widely across Africa. “Everyone is looking forward to getting it,” said Temwa Mzengeza, who oversees Malawi’s vaccine programs. Those eager for the shots include her husband, whom she had to stop from trying to get them, she said.Mzengeza used to come down with malaria several times a year until she started following her own advice to sleep under a net every night. Unlike many other kinds of infections, people can get malaria repeatedly, building up only a partial immunity.In the pilot program that began last year, 360,000 children in the three countries are meant to be vaccinated annually. The first dose is given at about age 5 months and the final, fourth booster near the child’s second birthday.Experts say it is too early to know how well the vaccine is working. They’re watching for malaria deaths, severe infections and cases of meningitis, something reported during studies but not definitively linked to the vaccine.“To do something completely new for malaria is exciting,” said researcher Don Mathanga, who is leading the evaluation in Malawi. The rainy season has brought new challenges, making some rural roads impassable and complicating efforts to track down children due for a shot. So far in Malawi, the first dose reached about half of the children targeted, about 35,000. That dropped to 26,000 for the second dose and 20,000 for the third. That’s not surprising for a new vaccine, Mzengeza said. “It will pick up with time.”At the health clinic in Migowi in Malawi’s southern highlands, workers see signs of hope. Henry Kadzuwa explains the vaccine to mothers waiting at the clinic. He said there was a drop in malaria cases to 40 in the first five months of the program, compared to 78 in the same period in 2018.Even though he wishes his 3-year-old daughter, Angel, could receive the vaccine, “it’s protecting my community. It also makes my work easier,” Kadzuwa said. The Migowi area has one of the country’s highest rates of malaria, and a worn paper register in the clinic’s laboratory lists scores of cases.At the clinic, Agnes Ngubale said she had malaria several years ago and wants to protect her 6-month-old daughter, Lydia, from the disease.“I want her to be healthy and free,” she said. “I want her to be a doctor.”And she has memorized the time for Lydia’s second dose: “Next month, same date.”___Neergaard reported from Washington.___The Associated Press Health and Science Department receives 7200

Alan Turing, a crack code-breaker and visionary mathematician who was convicted under Victorian-era homophobic laws, will be the face of Britain's new ￡50 note.Bank of England Governor Mark Carney announced Monday that Turing, who killed himself in 1954 after he was subjected to chemical castration, will appear on the new polymer note by the end of 2021.In a statement, Carney lauded the Englishman as an "outstanding mathematician" and "a giant on whose shoulders so many now stand.""As the father of computer science and artificial intelligence, as well as war hero, Alan Turing's contributions were far ranging and path breaking," the central banker said.Turing is best known for his work at Bletchley Park, where UK cryptologists sought to decipher messages sent by the Nazis. His efforts to crack Germany's Enigma code were the subject of the 2014 film "The Imitation Game."He also played a pivotal role in developing computers, and early thinking about artificial intelligence.In 1937, he published a paper introducing an idea that came to be known as the Turing machine, which is considered to have formed the basis of modern computing. This was a hypothetical device that could come up with a solution to any problem that is computable.The note's design reflects Turing's work. It features a ticker tape of binary code that spells out his birthday (June 23, 1912), and depicts the "British Bombe" machine that helped break the Enigma code.It also includes a quote Turing gave to The Times newspaper in 1949: "This is only a foretaste of what is to come, and only the shadow of what is going to be."Supporters have long campaigned for Turing to receive greater recognition for his work and official acknowledgment that his conviction for homosexual activity was wrong.Two years after choosing castration to avoid a custodial sentence, he ended his life at the age of 41 by eating an apple laced with cyanide.Sex between men over the age of 21 was decriminalized in England and Wales in 1967. However the law was not changed in Scotland until 1980 and in Northern Ireland until 1982.British Prime Minister Gordon Brown apologized for Turing's treatment by the justice system in the 1950s after thousands of people signed a petition in 2009.He received a royal pardon in 2014. 2295