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This is really a law for people who are very sick, who have exhausted all treatment options and who cannot enroll in a clinical trial, said Starlee Coleman, senior policy adviser at the Goldwater Institute, a conservative public policy think tank based in Phoenix that supports right-to-try legislation."For people living in a state where right-to-try is already on the books, they already have the ability today to work with their doctors directly to approach a drug company with a drug in clinical trials and ask for the option to try that drug outside of the clinical trial," she said. "For people living in the 12 states without a right-to-try law, today they don't have this option, but if the federal law passes, they will have the option."Some opponents argue that the bill won't change much but could have a detrimental effect on how the FDA safeguards the health of the public.Dr. Steven Joffe, professor in medical ethics and health policy at the University of Pennsylvania's Perelman School of Medicine, co-authored a perspective paper about such concerns, published in the New England Journal of Medicine last month.The paper notes that the FDA already has expanded-access policies, sometimes called compassionate use, to give terminally ill patients without other options access to investigational medical products outside of clinical trials.About 99% of submitted applications for expanded access to almost 9,000 investigational drugs were allowed to proceed over a 10-year period between January 2005 and December 2014, according to a study by FDA researchers, published in the journal Therapeutic Innovation & Regulatory Science in 2016."Emergency requests for individual patients are usually granted immediately over the phone and non-emergency requests are generally processed within a few days," FDA Commissioner Dr. Scott Gottlieb said in a statement last year. 1885

Trump and McGahn went weeks without speaking at the beginning of this year, and months without meeting one-on-one, people familiar with the matter said. During this period, along with telling people McGahn was "a leaker," Trump complained about McGahn's good relationship with Deputy Attorney General Rod Rosenstein, who oversees the special counsel investigation.This summer, Trump has stopped raising McGahn's relationship with Rosenstein as frequently, a person familiar with the matter said. The two men resumed one-on-one meetings around the latest Supreme Court nomination efforts, though one person familiar with the dynamic between them compared the duo to "old married couple complaining about each other."McGahn -- who, as White House counsel, makes a fraction of the money he was making as a lawyer at Jones Day -- has long viewed his role as laying the groundwork for Trump's legacy-making moves. He's also had a hand in the administration's deregulation efforts, which are sweeping.But, as White House counsel, he has not played a major role in directing the President's legal maneuvering when it comes to the Russia investigation. He was skeptical of the initial strategy, laid out by Trump's ex-lawyers Ty Cobb and John Dowd, of cooperating fully with Mueller's team. McGahn was a main internal advocate of bringing aboard Emmet Flood, who now directs the Russia legal strategy from inside the White House. Flood is viewed as a potential replacement for McGahn should he depart as White House counsel.With details of McGahn's participation with the special counsel made public, experts say it's only a matter of time before other Trump aides seek out Mueller for interviews."Nobody wants to be the last one standing," said Jack Quinn, who served as White House counsel under President Bill Clinton and is now a CNN legal analyst. "Nobody wants to watch one's colleagues go in, spill the beans and be the one who is last in line to cooperate. I think there is a good chance you will see a lot of people making phone calls to the special counsel's office asking when their interview can take place." 2112

Tragically, this is another case where officers were forced to make split-second decisions based on the actions of a violent individual, Moore told reporters. "This was a tense situation that unfolded very quickly and it's every officer's worst nightmare."The Van Nuys shooting happened a few weeks before the assistant manager of a Trader Joe's in Los Angeles was shot and killed by an officer's bullet. Melyda Corado was fatally shot as she left Trader Joe's while police exchanged fire with a gunman who later took hostages in the store.On June 16, officers responded to 911 calls about a man who had stabbed his former girlfriend inside a church in the Van Nuys neighborhood, police said.During the incident, officers fired 18 shots at suspect Guillermo Perez, 32, who was pressing a serrated knife against the throat of a woman standing outside the church.The woman, Elizabeth Tollison, who was 49 and homeless, was shot twice and died later at a hospital, police said.In the video released by LAPD, Perez -- a large kitchen knife in one hand and a metal folding chair in the other -- is seen moving toward officers. He refused numerous demands to drop the weapon.After a beanbag gun failed to stop the suspect, Perez moved toward Tollison and held the knife against her throat as three officers opened fire, according to the video."Was each round appropriate?" Moore asked. "That's the subject of this investigation and I will not comment on that until I have all the facts."Moore said the department was implementing new training procedures and expanding use of a nonlethal 40 millimeter launcher that fires a large foam baton intended to stop armed suspects."I spoke with members of Ms. Tollison's family and expressed our sadness at this horrible situation," Moore said. "Personally, my heart goes out to this victim's family and I also feel for the officers who were involved in this, as their lives will be forever changed."Moore said LAPD officers have long been trained to aim a "precise head shot" at suspects during hostage situations."The life of the hostage is paramount and protecting that individual from the threat of the assailant," he said. "In doing that, the balancing act the officer has is how to protect them by stopping the suspect's actions."Moore said the average number of shots fired by officers increased last year along with the number of officers involved in those shootings. The number of shootings in which suspects were armed with knives also increased, he said. 2510

This year’s Opening Day starter for the Padres is veteran lefty Clayton Richard. First pitch is scheduled for 1:10 p.m., and all fans at the game will receive a special Opening Day hat. 185

to show his brother he wasn't scared of him,'' according to statements Save" 153

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