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New tonight: And now the Trump campaign says it wants the president to debate Joe Biden in person on the originally planned dates. pic.twitter.com/bWqAdNZXUX— Kelly O'Donnell (@KellyO) October 9, 2020 208
New heart health research found that taking a low-dose daily aspirin to cut chances of a heart attack or stroke may have risks that outweigh the benefits.The latest studies revealed the effects of the blood-thinning, anti-inflammatory drug on patients, who did not yet develop heart disease or other heart-related issues but were at moderate risk.Research found aspirin does help patients with diabetes, who are at higher risk to develop or die from heart problems. However, the risk of serious bleeding far outweighed the benefit of taking the drug.The study found aspirin was not effective in preventing heart attacks or strokes for moderate risk patients, because they had other health issues, including high blood pressure, high cholesterol and smoking.Doctors also cautioned using fish oil supplements, instead of aspirin, would have similar disappointing results. Instead, health professionals suggest eating fish to improve your heart’s health.Fish oil may be more beneficial for people who have already suffered a heart attack. 1043
NIWOT, Colorado — The last of Crocs Inc.'s manufacturing facilities, located in Italy, is going to close, the company announced.It also closed its plant in Mexico. Crocs leaders did not give information on how it will continue producing its products during its second-quarter earnings report this week.The company grew its second-quarter earnings and revenue by 4.7 percent year-over-year. But Crocs Inc. is operating fewer stores.The company has not said if it plans to shutter more stores in the U.S. It expects revenue to increase, in the single digits, by the year's end. The cost of closing the manufacturing facilities in 2018 is million, the Daily Camera reports.Crocs Inc.'s chief financial officer, Carrie Teffner, plans to resign from the company effective April 1, 2019. Anne Mehlman will take her place. 857
New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccine.“Infection with this coronavirus does not necessarily generate lifetime immunity,” but antibodies are only part of the story, said Dr. Buddy Creech, an infectious disease specialist at Vanderbilt University. He had no role in the work, published Tuesday in the New England Journal of Medicine.The immune system remembers how to make fresh antibodies if needed and other parts of it also can mount an attack, he said.Antibodies are proteins that white blood cells called B cells make to bind to the virus and help eliminate it. The earliest ones are fairly crude but as infection goes on, the immune system becomes trained to focus its attack and to make more precise antibodies.Dr. Otto Yang and others at the University of California, Los Angeles, measured these more precise antibodies in 30 patients diagnosed with COVID-19 and four housemates presumed to have the disease. Their average age was 43 and most had mild symptoms.Researchers found that the antibodies had a half-life of 73 days, which means that half of them would be gone after that much time. It dovetails with a previous report from China also suggesting antibodies quickly fade.The results “call for caution regarding antibody-based ‘immunity passports,’ herd immunity, and perhaps vaccine durability,” the California authors write.That’s true, Creech said, but other parts of the immune system also help confer protection. Besides churning out antibodies, B cells develop a memory so they know how to do that again if needed.“They would get called into action very quickly when there’s a new exposure to the virus. It’s as if they lie dormant, just waiting,” he said.Other white blood cells called T cells also are better able to attack the virus the next time they see it, Creech said.Although circulating antibodies may not last long, what we need to know is if and how people remake antibodies if exposed to the coronavirus again and if they protect against another infection, Alison Criss, an immunologist at the University of Virginia, wrote in an email. “We also need to know if there is a protective T cell response” that reappears.Vaccines, which provoke the immune system to make antibodies, might give longer-lasting protection than natural infection because they use purified versions of what stimulates that response, she noted.Creech agreed.“This shouldn’t dissuade us from pursuing a vaccine,” he said. “Antibodies are only a part of the story.”___Marilynn Marchione can be followed on Twitter at http://twitter.com/MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2967
Nintendo has filed a lawsuit against an Arizona man after the video game giant claims he operated two websites "built almost entirely on the brazen and mass-scale infringement of Nintendo's intellectual property rights," according to court documents.The lawsuit, filed July 19 in Arizona U.S. District Court, claims Jacob Mathias and his company, Mathias Designs, L.L.C, operated 'LoveROMs.com' and 'LoveRetro.co' — websites lawyers for Nintendo say "are among the most open and notorious online hubs for pirated video games."The company claims Mathias posted thousands of Nintendo games on the sites that were downloadable as files — known as "ROMs" — and playable on phones or computers through software referred to as emulators. In court documents, the company's lawyers said Mathias uploaded an instructional video to YouTube explaining how to download and run the games.Nintendo estimates its titles were illegally downloaded from the sites by more than 60 million people.The company is seeking 0,000 for each infringement of its copyrighted work and up to ,000,000 for each infringement of the Nintendo trademark. Its lawyers said Mathias profited off the website through ad sales and donations.On Wednesday night, both 'LoveROMs.com' and 'LoveRetro.co' displayed messages they were shut down.Reached by phone, Mathias declined to comment. His attorney, Lance Venable, responded by email that he had "no comment at this time regarding the allegations" but added, "I have been in contact with Nintendo's counsel and we are hopeful that we can resolve the matter amicably." 1590
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