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Experts say the finalization of a COVID-19 vaccine is in our near future. Dr. William Moss is a professor of epidemiology and the executive director of the International Vaccine Access Center at the Johns Hopkins Bloomberg School of Public Health.“Remarkable progress has been made in the development of COVID-19 vaccines,” Dr. William Moss said.He says it typically takes five to 10 years to develop a vaccine, but with so much money and attention going toward COVID-19, he believes it’s likely we’ll have a vaccine by the end of the year.“I’m pretty confident that there will be a vaccine that will have an emergency-use authorization in the United States by the end of 2020,” Dr. Moss said.According to Dr. Moss, of the dozens if not hundreds of vaccine candidates in clinical trials, there are three vaccine candidates that have reached phase three. Phase three is when tens of thousands of volunteers test the vaccine to make sure it’s safe and effective.As of this week, we have optimistic news regarding phase-three efficacy results from biopharmaceutical company Pfizer – which has been collaborating with German company BioNTech.“Early preliminary results suggests that their vaccine is 90% or so effective in preventing mild to moderate or severe disease.”If the 90% efficacy data holds up after follow ups from participants in late November, Dr. Moss says he expects the FDA will rigorously review the data and approve the vaccine for distribution. That means health care workers and other high-priority groups would get the vaccine in December of this year, or early next year.“Pfizer says that they could have close to 50 million doses by the end of this year," Dr. Moss said. "Now remember their vaccine – as a number of the vaccine candidates do – requires two doses per individual. So, 50 million doses allows you to vaccinate about 25 million people.”Dr. Moss says the unprecedented investment in vaccine manufacturing will make it possible for the vaccine to be distributed so quickly. However, there are still quite a few logistical challenges since he says the Pfizer vaccine requires extreme cold temperatures as low as minus 117 degrees Fahrenheit.“So we need warehouses to store the vaccine that have freezers that can maintain that cold, we need transportation systems – planes, trucks – that can deliver the vaccine and keep it cold. And then at the site of distribution, we need to be able to keep these vaccines cold.”Therefore, he says it will likely take a lot longer for the general population to get the vaccine. He’s guessing not until the middle of 2021. Of course, the idea of saving lives with the help of a vaccine is very promising, but he says the greatest misconception is that we can go back to "normal" as soon as it’s distributed.“That by no means is going to indicate that we can go back to our pre-pandemic life," Dr. Moss said. "We will not know whether these vaccines stop transmission and we’re going to still need to wear masks, to wash our hands and physically distance even when vaccines become available.”Time and patience will be vital as we wait to see the long-term impacts of the vaccine in this pandemic. 3168
Facebook CEO Mark Zuckerberg will testify in front of a Congressional panel on April 11.He's set to appear before the House Energy and Commerce Committee next Wednesday at 10:00 a.m. ET to talk about the "company's use and protection of user data."Reps. Greg Walden and Frank Pallone, Jr., the chair and ranking member of the committee, respectively, said in a statement that the hearing "will be an important opportunity to shed light on critical consumer data privacy issues and help all Americans better understand what happens to their personal information online."CNNMoney broke the news last week that Zuckerberg was coming close to securing a date to testify before Congress. Facebook has been under fire after the revelation that the data firm Cambridge Analytica was able to access information from about 50 million Facebook users without their knowledge, and lawmakers have been clamoring for him to testify.The-CNN-Wire 938

ESCONDIDO (KGTV) - Driving into Escondido will soon have a much different feel. Construction is underway to build what leaders say will be an icon of the city.Spanning 108 ft wide, a new arch will be lifted 40 ft above the intersection of Grand Avenue and Centre City Parkway."Escondido is just the hidden jewel of North County; in fact, Escondido means hidden valley and beautiful hidden valley. We're starting to live up to that more than I've ever seen," said Dan Forster.Forster owns Design Moe Kitchen & Bath and has watched new blood elevate the historic downtown over the last ten years, including restaurants, breweries, and new businesses. Also vice president of the Escondido Downtown Business Association, Forster says they've wanted a grand sign like this for years, but he says it was cost-prohibitive. Forster says that changed with an anonymous million donation made to the Escondido Charitable Foundation for the arch. "There's no money that's being taken out of the city budgets to pay for this, it's just one big beautiful sign," said Forster. Crews will raise the sign on March 3. On March 12, the city will celebrate the Grand arch with entertainment and lighting of the new sign starting at 6 p.m. 1233
Excessively high or low body mass index measurements have been linked to an increased risk of dying from nearly every major cause except transport accidents, new research says.The?study, published Wednesday in The Lancet Diabetes and Endocrinology and conducted by scientists at London School of Hygiene and Tropical Medicine, revealed that BMI that's either too high or too low is tied to increased morbidity from a range of major diseases.Krishnan Bhaskaran, lead author of the study and associate professor of statistical epidemiology, noted that his team found "important associations" between BMI and most causes of death."BMI is a key indicator of health. We know that BMI is linked to the risk of dying overall, but surprisingly little research has been conducted on the links to deaths from specific causes," he said."We have filled this knowledge gap to help researchers, patients and doctors better understand how underweight and excess weight might be associated with diseases such as cancer, respiratory disease and liver disease."BMI is determined by dividing a person's weight in kilograms by the square of their height in meters.The study authors say they discovered that maintaining a BMI in the range of 21 to 25 kg/m2 is linked to the lowest level of morbidity.BMI outside this range was shown to have a "J-shaped association" with nearly all causes of death, not solely the most prevalent diseases. This means BMIs both lower and higher than the optimal range lead to increased risk of morbidity.The study, which analyzed data from 3.6 million people and 367,512 deaths, showed that obesity, or BMI of 30 or more, was linked to an increased prevalence of two major causes of death: heart disease and cancer."BMI higher than 25, the upper end of healthy, is linked to most cancers, most cardiovascular diseases, respiratory disease, and liver and kidney conditions," Bhaskaran said.Obesity was shown to reduce life expectancy by 4.2 years in men and 3.5 years in women, and it can contribute to other chronic conditions including respiratory disease, liver disease and diabetes.The British Journal of Cancer reported in April that obesity is linked to 7.5% of cancers in UK women.The charity Cancer Research UK estimated that 23,000 women will deal with obesity-related cancers by 2035. Obesity will also become the most common cause of cancer in women by 2043 if trends continue.The study also revealed that being underweight is linked to a "surprising wide range of deaths," including dementia, Alzheimer's, cardiovascular disease and suicide.However, Bhaskaran noted that links between low BMI and causes of death were more "observative," as it was less clear whether low weight was the direct cause of illness or rather a marker of poor health more generally.He also acknowledged the limitations of the study, which included a lack of information on the diet or level of physical activity of the individuals involved and the impact these factors may have had on morbidity.He nevertheless noted that the findings reiterated the importance of maintaining a BMI within the 21 to 25 range. 3130
Even a parked car is a source of stress.Like when you run outside in your pajamas at the sound of the street sweeper coming. Cars left unattended for days might become a target for theft or vandals. They still need routine maintenance, the occasional car wash and a drive every few weeks to circulate the fluids and recharge the battery.So with the pandemic changing the way we work, commute and shop, there’s probably no better time to see what life feels like without a car.Here are four reasons to consider a car-free future:1. You don’t (and won’t) drive much anymoreHow many days last week did your car just sit? How many miles have you put on it in the past month?When the pandemic hit, many companies sent their employees home to work remotely. Total miles driven plunged by 40% nationally in the second half of March, according to insurance data analyst Arity. Driving is on the rise again, but the interlude showed that we can get along just fine without everyone having their own car.But you’re still making the same car payment as when you drove every day.2. You have better uses for that moneyAmericans have long been encouraged to overspend on cars, urged on by ads that promise the right car will make us popular or rugged and unlock the freedom of the great outdoors.The average American spent 3.50 a month, or ,282 a year, on their car in 2019, according to AAA. That’s mainly because car payments are so high: Experian says in 2019 the average monthly payment for a new car was 4, and the average for a used vehicle was 1.If you’re struggling to make ends meet, ditching the car payment would be a huge savings, not to mention the related expenses of gas, insurance, maintenance and repairs. If you’re not hurting, that’s money that can go toward a home down payment, a Roth IRA or paying down debt.Why not take a look at exactly how much you pay — and how much you could save — with our handy total cost of ownership calculator?3. You can cash in on high used car pricesIf you do decide to part with your car, it’s a seller’s market. The average price of a used car listing rose by 8 from June to July, according to Edmunds, which called the trend “an unprecedented historical shift in the used vehicle market.”Year over year, the value of used cars is up 16%, according to auctioneer Manheim’s Used Vehicle Value Index.More good news: Selling your used car is easier than ever. Online used car retailers such as Carvana, Shift and Vroom will give you an upfront price and pick up your car from your home. Or, sell your car to a local dealer who’s probably hungry for trade-ins for the used car lot.If you sell, consider protecting your assets with a non-owner car insurance policy. It offers liability protection if you borrow or rent a car and the owner’s own limits are exceeded. And if you were to buy another car yourself, you wouldn’t be penalized for a gap in insurance coverage.4. You have options when the need arisesThe pandemic has opened our eyes to the possibilities of delivery: groceries, takeout meals, school supplies and area rugs.And to the joys of walking, too. What’s within walking or cycling distance? A few minutes with Google Maps might surprise you.Car trips of less than a mile add up to 10 billion miles a year, according to the Environmental Protection Agency. Replacing those trips with walking or biking will not only help keep you fit, but also save you money on gas and cut down on pollution.But sometimes you still need a car. Many transportation services that were initially locked down are up and running, offering contactless service at reduced prices with new safety measures.Here’s what’s available for longer-than-cycling distances:Taxis and ridesharing services.Car-sharing companies such as Zipcar.Rides from a friend.Rental cars and peer-to-peer car rental sites such as Turo.Public transportation.More From NerdWalletHow to Pay for a Home Remodel Without Tapping Your EquityShould You Press Pause on Private Student Loans?Is That Nearly New Salvage-Title Car Really a Deal?Philip Reed is a writer at NerdWallet. Email: articles@nerdwallet.com. Twitter: @AutoReed. 4147
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