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BERLIN, June 8 (Xinhua) -- The deadly strain for the E. coli outbreak was found again on cucumbers, authorities of German state Saxony-Anhalt said on Wednesday. The strain O104 was found on the scraps of cucumbers in a dustbin in the eastern city of Magdeburg, said State Health Minister Holger Paech.The dustbin belongs to a family in which three members have been ill. Paech said. The father only suffered a slight stomach upset, while the mother was once treated at a hospital and is now released. Their daughter is suffering from hemolytic-uremic syndrome (HUS), a serious complication from the infection of E. coli.However, experts were not clear about how the bacteria came to the cumbers, which have been in the dustbin for a week and a half."It is not clear and we are not able to determine how it reached there." Paech said.German authority first detected such bacteria from Spanish cucumbers on May 26, which has been overthrown by the laboratory tests in Hamburg last Tuesday.On Sunday, German State Lower Saxony issued a warning on bean sprouts as a possible source for the outbreak, which was proven to be negative on Monday.The German government has faced increasing criticism from abroad and at home for dealing with this crisis, as it has wrongly blamed the source of the infection for twice and there is a lack of coordination between different research institutes on the outbreak.John Dalli, European Union Health Commissioner, was quoted by local daily Die Welt saying "we have to rely on the experience and expertise across Europe, and even outside Europe."The Max Planck Institute for Infection Biology in Berlin also called for a federal government representative to coordinate the various government agencies which are dealing with the crisis.A federal government representative could increase cooperation between ministries and reduce mixed messages from the government, said director Stefan Kaufmann.On the same day, Germany's national disease control center, the Robert Koch Institute, said the number of infection has shown an overall decreasing trend but it is still uncertain whether the decline is due to people staying away from vegetables or to the waning of the source of infection.Until Wednesday, 25 deaths have been reported while the infection cases have increased more than 2,600 in 12 countries around the world.

WASHINGTON, Sept. 13 (Xinhua) -- The U.S. Department of Health and Human Services (HHS), with several partners, on Tuesday launched Million Hearts, an initiative that aims to prevent one million heart attacks and strokes over the next five years.The program will focus on helping Americans make healthy choices, such as preventing tobacco use and lowering consumption of salt and trans fats, and increasing use of treatments like aspirin and blood pressure and cholesterol-lowering medications.The HHS hopes that by 2017, 65 percent of high-risk patients will be taking aspirin and have their blood pressure and cholesterol under control. Currently, only 47 percent of high-risk patients take aspirin, and only 33 percent have their cholesterol and 46 percent their blood pressure under control.They also aim to cut smoking to 17 percent of Americans from 19 percent by 2017, and seek a 20 percent drop in sodium intake and a 50 percent drop in trans fat consumption."Heart disease causes one of every three American deaths and constitutes 17-percent of overall national health spending," said HHS Secretary Kathleen Sebelius in a statement. "By enlisting partners from across the health sector, Million Hearts will create a national focus on combating heart disease."

BEIJING, June 10 (Xinhua) -- The nation's drug watchdog on Friday publicized a draft national standard of sulfur dioxide residue in Chinese herbal medicine, which is open for public opinion until Sept. 9 this year.The maximum amount of sulfur dioxide residue is 400 mg in one kg of each of 11 specified kinds of herbal medicine, such as Chinese yams, Gastrodia elata and Codonopsis pilosola, according to the draft standard unveiled by the State Food and Drug Administration (SFDA).The standard provides a 150-mg-per-kg limit for all other kinds of herbal medicine.Fumigation with sulfur is used as a way of drying some herbal medicine by growers, and currently have no alternative that is both cheap and convenient.The SFDA said it doesn't favor the drying herbal medicine through fumigation with sulfur and urges research efforts to invent new alternatives.According to the World Health Organization, the tolerable maximum amount of sulfur dioxide that a human body can take in one day is 0.7 mg per kg, which means that an adult of 60 kg should not take in more than 42 mg of sulfur dioxide a day.Long-term exposure to high amounts of sulfur dioxide can cause damage to human body, especially the respiratory system, according to experts. 

WASHINGTON, Aug. 2 (Xinhua) -- The weakness of aging is associated with leaky calcium channels inside muscle cells and a drug already in Phase II clinical trials for the treatment of heart failure might plug those leaks, according to a report published Tuesday in the online edition of Cell Metabolism.Earlier studies by the research team led by Andrew Marks of Columbia University showed the same leaks underlie the weakness and fatigue that come with heart failure and Duchenne muscular dystrophy."It's interesting, normal people essentially acquire a form of muscular dystrophy with age," Marks said. "The basis for muscle weakness is the same." Extreme exercise like that done by marathon runners also springs the same sort of leaks, he added, but in that case damaged muscles return to normal after a few days of rest. A microscopic view shows smooth muscle cells derived from human embryonic stem cells showing the nuclei (blue) and proteins of the cytoskeleton (green) in this handout photo released to Reuters by the California Institute for Regenerative Medicine, March 9, 2009The leaks occur in a calcium release channel called ryanodine receptor 1 (RyR1) that is required for muscles to contract. Under conditions of stress, those channels are chemically modified and lose a stabilizing subunit known as calstabin1.Calcium inside of muscle cells is usually kept contained. When it is allowed to leak out into the cell that calcium itself is toxic, turning on an enzyme that chews up muscle cells. Once the leak starts, it's a vicious cycle. The calcium leak raises levels of damaging reactive oxygen species, which oxidize RyR1 and worsen the leak.The researchers made their discovery by studying the skeletal muscles of young and old mice. They also showed that 6-month-old mice carrying a mutation that made their RyR1 channels leaky showed the same muscular defects and weakness characteristic of older mice.When older mice were treated with a drug known as S107, the calcium leak in their muscles slowed and the animals voluntarily showed about a 50 percent increase in the amount of time spent wheel running. Now in clinical trials for patients with heart failure, the drug is known to work by restoring the connection between costabilin and RyR1.Despite considerable effort to understand and reverse age- related muscle wasting, there are no established treatments available. The new work suggests there may be hope in approaching the problem from a different angle."Most research has focused on making more muscle mass," Marks said. "What's different here is that we are focused not on muscle mass but on muscle function. More muscle doesn't help if it is not functional."

BEIJING, Aug. 22 (Xinhuanet) -- Researchers have discovered how a human egg captures an incoming sperm for fertilization, paving the way to help couples suffering from infertility, according to media reports on Monday.An international team of researchers found that a sugar chain known as the sialyl-lewis-x sequence (SLeX) makes the outer coat of the egg “sticky,” which has proven to be helpful in binding the egg and the sperm.As a result, this observation has filled in a huge gap in the understanding of fertility and provides hope for ultimately helping couples who currently cannot conceive.Scientists and doctors know that a sperm identifies an egg when proteins on the head of the sperm match and bind to a series of specific sugars in the egg’s outer coating. With a successful match of proteins, the outside surfaces of the sperm and egg then bind together before merging, which is then followed by delivery of sperm’s DNA into egg.To identify this molecules, the researchers used ultra-sensitive mass-spectrometric imaging technology to observe and identify which molecules are most likely to be key in the binding process.They experimented with a range of synthesised sugars in the laboratory and found that it is SLeX that specifically binds sperm to an egg.According to the World Health Organisation, infertility affects about 15 percent of reproductive-aged couples around the world and almost one in every seven couples in Britain has problems conceiving a child for various reasons.