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LOS ANGELES (CNS) - USC researchers have found the likely order in which COVID-19 symptoms first appear: fever, then cough and muscle pain, followed by nausea, and/or vomiting, and diarrhea, it was announced Thursday.Knowing the order of COVID-19's symptoms may help patients seek care promptly or decide sooner than later to self isolate, according to scientists at the USC Michelson Center for Convergent Bioscience. The information also may help doctors rule out other illnesses, or help doctors plan how to treat patients, and perhaps intervene earlier in the disease.The study, which appears in the journal Frontiers in Public Health, was led by doctoral candidate Joseph Larsen and scientists Peter Kuhn and James Hicks at the USC Michelson Center's Convergent Science Institute in Cancer."This order is especially important to know when we have overlapping cycles of illnesses like the flu that coincide with infections of COVID-19," said Kuhn, a USC professor of medicine, biomedical engineering, and aerospace and mechanical engineering. "Doctors can determine what steps to take to care for the patient, and they may prevent the patient's condition from worsening."Fever and cough are frequently associated with a variety of respiratory illnesses, including influenza, Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome. But the timing and symptoms in the upper and lower gastrointestinal tract set COVID-19 apart."Given that there are now better approaches to treatments for COVID- 19, identifying patients earlier could reduce hospitalization time," Larsen said.To determine COVID symptom chronology, the authors analyzed more than 55,000 confirmed coronavirus cases in China collected from Feb. 16 to Feb. 24 by the World Health Organization. They also studied a dataset of nearly 1,100 cases collected from Dec. 11 through Jan. 29 by the China Medical Treatment Expert Group via the National Health Commission of China.In addition, to compare the order of COVID-19 symptoms to influenza, the researchers examined data from 2,470 cases in North America, Europe and the Southern Hemisphere, which were reported to health authorities from 1994 to 1998."The order of the symptoms matter, " Larsen said. "Knowing that each illness progresses differently means that doctors can identify sooner whether someone likely has COVID-19, or another illness, which can help them make better treatment decisions." 2440

LOS ANGELES (AP) — Voters who hate resetting their clocks twice a year took the first step Tuesday to making daylight saving time year-round in California.With nearly 4.5 million ballots counted, Proposition 7 led by more than 62 percent. The measure permits the state Legislature to establish permanent daylight saving time. However, a change in federal law would be required before the initiative can take effect.The time-change issue was fresh on voters' minds when they went to the polls. California and most of the rest of the nation reset clocks last Sunday, falling back on standard time and seeing the day get dark one hour earlier.Democratic Rep. Kansen Chu of San Jose said last month that he sponsored Proposition 7 after his dentist called him to complain about springing forward when clocks are moved up an hour every March. That switch takes away an hour's sleep in the middle of the night as it shifts an hour of sunlight from the morning to the evening.Chu said he investigated the issue further and learned the original reason for implementing daylight saving — to save energy during World War I— no longer seemed to apply to the modern world.Chu said he also came across studies showing an increased risk of car accidents and heart attacks following the spring change when people lose an hour of sleep."It's a public safety measure," Chu said. "And I don't know anybody who really enjoys doing this adjustment of their schedule twice a year."Opponents argued that even if California voters and the Legislature approve year-round daylight saving, the hurdle of getting the federal government to agree is too high given the state's tense relationship with Washington.RELATED CONTENT 1706

LOS ANGELES, Calif. – A judge has denied a request from Britney Spears to end her father’s conservatorship over her estate, though the pop star did score small victories in the case.Los Angeles Superior Court Judge Brenda Penny declined to suspend James “Jamie” Spears from his central role in the court conservatorship, but said she would consider future petitions for his suspension or outright removal, The Associated Press reports.Spears’ attorney, Samuel D. Ingham III, said he plans to file those petitions.The judge also approved a request from Spears for a corporate fiduciary, the Bessemer Trust, to now serve as co-conservator with her father.During Tuesday’s contentious court hearing, Ingham said his client fears her father and won’t resume her career as long as he has power over it. The 38-year-old singer has been on a hiatus since early 2019.A lawyer for Spears’ father argued during the hearing that he has been an excellent conservator and has taken his daughter from being in debt to being worth more than million.Spears’ conservatorship has been in place since 2008, when the star experienced mental health issues and her public meltdowns were widely reported on. Since then, however, she has made a comeback in her career and held a residency in Las Vegas.Legal experts told the Los Angeles Times that it’s unusual for someone as young and productive as Spears to be in this type of situation for so long and that conservatorships like these are usually used to protect the old, infirm or mentally disabled.The L.A. Times reports that another hearing in the case is set for Dec. 16. 1616

LOS ANGELES (CNS) - TV actress Lori Loughlin will serve her prison sentence at the federal correctional institution in Victorville for her role in the college admissions scandal, according to court papers obtained Thursday.A judge signed off on the actress' request to serve her time at the medium-security federal prison camp, according to a Sept. 9 order filed in Boston federal court.Loughlin's husband, clothing designer Mossimo Giannulli, will serve his sentence at the low-security federal prison for men at Lompoc in Santa Barbara County.Loughlin was sentenced on Aug. 21 to two months behind bars -- hours after her husband was handed a five-month term -- for paying 0,000 in bribes to get their daughters admitted to USC as crew team recruits, even though neither girl played the sport.U.S. District Judge Nathaniel M. Gorton ordered the "Full House" star and her husband to self-surrender at their respective prisons on Nov. 19 to begin serving their time.Loughlin was also ordered to pay a 0,000 fine and serve two years of supervised release with 100 hours of community service.Along with his prison term, Giannulli was ordered to pay a 0,000 fine and serve two years of supervised release with 250 hours of community service.Victorville prison camp inmates are housed in "open bay" dormitories, two and four-person cubicles, and four-person rooms. Job positions involve driving, working in food and trash services, plumbing, painting, grounds keeping and education. The institution also operates an auto parts warehouse employing three-dozen female inmates providing inventory services, according to the camp's website.At sentencing, Loughlin told the court that she had "made an awful decision. I went along with a plan to give my daughters an unfair advantage in the college admissions process."The couple were accused of paying half a million dollars in bribes to the admitted mastermind of the scheme, college admissions counselor Rick Singer, to get their daughters, Olivia Jade and Isabella Rose Giannulli, accepted into USC as crew recruits.After a year of insisting on their innocence, the 56-year-old actress pleaded guilty in May to one count of conspiracy to commit wire and mail fraud, while her husband pleaded guilty to one count of conspiracy to commit wire and mail fraud and honest services wire and mail fraud.As part of the scheme, they sent fake crew recruiting profiles to Singer that included bogus credentials, medals and photos of one of their daughters on a rowing machine. Neither daughter is now enrolled at USC.According to prosecutors, evidence shows that Giannulli, 57, was the more active participant in the scheme."He engaged more frequently with Singer, directed the bribe payments to USC and Singer, and personally confronted his daughter's high school counselor to prevent the scheme from being discovered, brazenly lying about his daughter's athletic abilities," federal prosecutors wrote."Loughlin took a less active role, but was nonetheless fully complicit, eagerly enlisting Singer a second time for her younger daughter, and coaching her daughter not to `say too much' to her high school's legitimate college counselor, lest he catch on to their fraud," they wrote.More than 50 people have been charged in the probe, which investigators dubbed operation "Varsity Blues." Of 38 parents charged, 26 have pleaded guilty and received sentences ranging from the two weeks given to "Desperate Housewives" star Felicity Huffman to a nine-month term imposed on Doug Hodge, former head of a Newport Beach-based bond management firm.Huffman was released Oct. 25 from a low-security federal prison camp in Northern California 11 days into a 14-day sentence for paying to have a proctor correct her daughter's answers on a college-entrance exam. 3804

LOS ANGELES (CNS) - Sheriff Alex Villanueva Tuesday said a weekend raid of "a massive underground party" at a vacant Palmdale residence -- despite health restrictions against large gatherings and a statewide curfew in place due to the coronavirus pandemic -- led to 158 arrests and the rescue of a 17- year-old victim of human trafficking.The Saturday night party in the 6300 block of West Avenue M-8 was allegedly organized by a teen promoter who was one of the people arrested when sheriff's deputies descended on the event, Villanueva said."Parties like these often involve drugs, prostitution, underage drinking and violence," Villanueva said at a news conference Tuesday morning outside the Hall of Justice, where he announced the 158 arrests as well as the rescue of the human trafficking victim and the recovery of six firearms from the location."We were able to rescue a girl who was present and categorized as a commercially sexually exploited child," Villanueva said.Involved in the law enforcement operation were personnel from the sheriff's Palmdale Station, the Human Trafficking Task Force, Operation Safe Streets Bureau, Aero Bureau, three mobile field forces and Los Angeles County Fire Department paramedics.According to Fox11, which had been tracking the 17-year-old promoter's alleged activities and was on scene when the raid occurred, 116 adults were cited and released for various misdemeanor offenses, while seven people were booked into jail. Another 35 juveniles were also cited and released. The arrests included three adults and two juveniles booked on suspicion of burglary, while one juvenile was arrested on a gun charge, the station reported.When stricter health orders were announced last week, including plans for the state's regional stay-at-home order that took effect late Sunday night, Villanueva said his department would continue to rely on the public's adherence to restrictions."Since March, we have continued to focus on education and voluntary compliance regarding health orders," he wrote on Twitter. "Moving forward, we will additionally be conducting targeted enforcement of super-spreader events."The Palmdale party was considered just such an event, Villanueva said at the news conference."As you can see, this was a flagrant violation of the governor's health order," Villanueva said. "But also please understand, even without the health order, these actions were criminal in nature."Villanueva said COVID-19 protocols were maintained by the law enforcement personnel, including providing those who were detained with protective masks.Sheriff's Capt. Ron Shaffer said the homeowner did not give permission for the residence to be used for such a gathering."They were looking to rent it to a family," Shaffer said.According to Fox11, the residence used for the party was up for rent, but the party organizers were allegedly in the home illegally.Los Angeles County and state health restrictions in place due to the coronavirus ban gatherings with people from different households. State health orders that were in place on Saturday also included an overnight curfew, barring people from gathering with others between 10 p.m. and 5 a.m. 3191