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SAN DIEGO (KGTV) -- We’ve known for a while that COVID-19 hits people over 65 especially hard, but a study published Wednesday from researchers in San Diego offers new insight into why that happens.The numbers are staggering: if you’re 65 or older, your risk of winding up in the hospital from COVID-19 is five to 11 times higher than someone under 30. Your risk of death is at least 90 times higher, according to data from the Centers for Disease Control and Prevention.Researchers at the La Jolla Institute for Immunology say the reason why older people fare so much worse appears to be from a lack of T-cells, a type of white blood cell that can decline with age.“Some viruses get controlled by one part of the immune system. Some viruses get controlled by another. In this case it seems that T-cells really do a lot of the work,” said Dr. Shane Crotty, one of the authors of the study published Wednesday in the journal Cell.Dr. Crotty and his colleagues looked at 50 people infected with the virus, and they measured the three elements of the adaptive immune system in detail: antibodies, helper T-cells and killer T-cells.Then they compared the measurements to how people fared against the virus. Some patients in the study group had severe cases, others had mild infections.The researchers found that people with all three branches of the adaptive immune system tended to fully recover. People with severe cases of the virus often lacked one or more of the immune branches, and it was particularly evident in older people.“Our data indicated that of the older individuals, it was particularly the ones that had fewer T-cells to start that look like they really struggled to control this virus,” Dr. Crotty said.As we age, we have fewer T-cells to send after invading pathogens. “That collection of T-cells gets smaller. So it’s harder to recognize a new virus,” Crotty said.Among the 748 deaths in San Diego County reported as of Wednesday, 87% were people aged 60 and older.The findings from LJI may have implications in the search for a vaccine against COVID-19. The data suggests that vaccine-makers may want to target a drug that elicits all three branches of the immune response, Dr. Crotty said. Some vaccine approaches, such as inactivated virus vaccines, only elicit two of three branches, not killer T-cells. However, Crotty said it was too soon to rule any candidates. Two strong branches produced by a vaccine could potentially cover for the lack of a third, he said.Crotty said the findings could help vaccine-makers interpret results from the clinical trials and find the right dosing.“Is a given vaccine a good vaccine, and you just need a booster immunization?” he said. “Does it work well in one population but it doesn’t help in the elderly because it doesn’t generate a T-cell response, for example? Those are the scenarios when this type of knowledge will come into play.” 2906

SAN DIEGO (KGTV)- Across California, many businesses continue to struggle in San Diego County, and some business owners say they can’t afford to pay their rent anymore without their usual income during this pandemic.Landlords are also feeling the effects of the small business struggle.“Many tenants are paying their rents, there aren’t many tenants paying their rents from profits,” said Sandy Sigal, CEO of NewMark Merrill Companies. “We’re not going to make any money or have any profits this year at all, we know that, but we do need enough money to pay our mortgages and lenders.NewMark Merrill Companies own about 80 shopping centers in three states, including California. They own 12 shopping centers in San Diego County, from Oceanside to Chula Vista.Sigal said many of his tenants had been hit hard during this pandemic, especially in California.“The category type that we’ve lost lots of tenants are the nail and hair salons, very often run by mom and pops,” he said.In San Diego County, the following seven tenants have closed their businesses permanently.Expedia – Terra Nova Plaza in Chula VistaSouplantation – Piazza Carmel in San DiegoSouplantation - Chula Vista Crossings in Chula VistaPronto Insurance – Tri-City Crossroads in OceansideElements Massage – Nordahl Marketplace in San MarcosShape Threading – Nordahl Marketplace in San MarcosKeller Williams – Rancho Bernardo Village in San Diego“We did what we could to help tenants where they needed it,” said Sigal. “If you’re a small restaurant and you had to close, you were closed for 3 to 4 months; we did what we could to help you, which included rent deferrals and helping you apply for those PPP loans. We bought tarps. We bought fans, and we bought artificial turf. We’re doing what we can.”But Sigal said landlords could only do so much, and it’s up to the government to step in and help save these businesses.“If there was a fire or earthquake or flood, they would have insurance for all this,” he said. “We need to extend what was PPP or The RESTART Act. I’m in favor of some stimulus to the unemployed.”Without additional assistance now, it’s a struggle he expects to continue until significant changes are made, and businesses can fully bounce back.“If the government helps my tenants, I’d be helped enough,” he said. “This is no one’s fault, but the pandemic and we all got to get through this together.” 2393

SAN DIEGO (KGTV) — Vehicles remain one of the top causes of wildfires in San Diego County, according to numbers released by Cal Fire.Most recently, the Carr Fire that burned thousands of acres in Redding, Calif., was blamed on a flat tire leading to a car's wheel rim scraping on the asphalt.In San Diego County, vehicles remain the top two causes of wildfires, officials said. This could be due to a faulty catalytic converter, metal chains, or even pulling over in a brushy, dry area on the side of the road.RELATED: SDG&E's Skycrane helicopter facing challenging fire season in San Diego County"People just need to be really cognizant and think about the fire danger risk when they’re driving and need to pull over,” Kendal Bortisser, CAL FIRE and County Fire captain, said. "Sometimes people are unaware that if they pull off the road and there’s grass, it could catch fire.  It could be a really bad move."In 2016, local wildfires were caused by: 969

SAN DIEGO (KGTV) -- With a global pandemic and calls for social justice and equity, 2020 was a year full of change. We all were required to think quickly and adapt. It forced us to think long and hard about our values and what we can – and are called to – do, as organizations and individuals.What has the impact been on our careers and long-term plans? How have organizations changed how and who they hire? Are new skill sets in demand?Is there a more thoughtful approach to diversity and inclusion? And what about our young people – are they rethinking their plans, and what they imagine for their lives and careers?Our featured speakers this week include executive coach Azadeh Davari, executive recruiter Trevor Blair, and Reality Changers CEO Tamara Craver. The conversation will be moderated by LEAD Vice President Elizabeth Fitzsimons.WHEN: December 9 @ 2:00 pm - 3:00 pmJOIN VIA ZOOM: https://sdchamber.org/event/webinar-series-leading-in-a-new-reality-7/WATCH ON FACEBOOK: https://www.facebook.com/ABC10News/ 1025

SAN DIEGO (KGTV) — While many San Diego County voters will be returning their mail-in ballot via the postal service, many will also utilize official drop-off locations throughout the county.Voters can choose from 126 official sites, including 79 different library locations throughout the county and the Registrar of Voters, from Oct. 6 to Nov. 3. A full list of official drop-off locations is available online.An online map search to find your closest location is also online here.RELATED: Step-by-step guide to voting by mail or in-person in San Diego CountyVoters who choose to drop off their ballot or vote in person at the Registrar of Voters can visit the location at 5600 Overland Avenue. The office is open 8 a.m. through 5 p.m. Monday through Friday. On Election Day, the office will be open from 7 a.m. to 8 p.m. The registrar is closed on the weekend.If a voter chooses to have someone drop off their mail-in ballot for them, they must fill out the "person authorized to return" section in the top right portion of the ballot's envelope:Voters can also return their mail-in ballot to any official polling place between Oct. 31 through Election Day. Voters can search for their official polling place online here. 1231

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