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Immunotherapy has gained ground against a stubborn opponent: ovarian cancer. A personalized cancer vaccine is safe and may lengthen the lives of ovarian cancer patients, a small clinical trial found.The research, published Wednesday in the journal Science Translational Medicine, showed "significantly higher" overall survival at two years among patients who received the vaccine, compared with patients who did not.Ovarian cancer is a "silent killer" because often it goes unnoticed until it is diagnosed at a late stage. Treated with surgery followed by chemotherapy, most patients -- 85% -- relapse and ultimately develop resistance to the chemo. At this point, they run out of treatment options.Still, scientists are hopeful based on the fact that a subset of patients shows an immune response to their cancer. Generally, these patients have better survival rates than those whose immune systems don't react in the same way.A vaccine, then, might be able to trigger and boost the immune system and increase the survival rates of patients, said Dr. Lana Kandalaft, senior author of the new study and an adjunct assistant professor at the University of Pennsylvania Perelman School of Medicine.  1210

House Majority Leader Kevin McCarthy plans to introduce legislation this week that will fully fund President Donald Trump's proposed wall along the U.S.-Mexico border with a whopping .4 billion price tag, a spokesperson for the California Republican told CNN on Tuesday.The bill is still in the drafting process but is expected to be released within the next few days in the pro-forma session this week. The House remains in recess until mid-November, after the midterm elections, so the body would not consider the legislation for another month or so. Even with a Republican-controlled Capitol Hill and White House, any proposal to fully fund Trump's signature campaign pledge of a border wall would have a difficult pathway to passing both chambers of Congress, given the threshold for such legislation and the narrow margin of control in the Senate.The legislation comes as McCarthy is headed to the U.S.-Mexico border on Wednesday for a tour and briefing by the Department of Homeland Security and as the California congressman continues to push to succeed Speaker Paul Ryan when the Wisconsin Republican departs in January.Mccarthy is not the only House Republican to express interest in leading the caucus. Majority Whip Steve Scalise of Louisiana and House Freedom Caucus co-founder Jim Jordan of Ohio have talked about pursuing the top House GOP spot, and both are traditionally affiliated with the more conservative side of the caucus members. Scalise has said he would not run to lead the party if McCarthy does, but Jordan has already announced his intention to seek the position.McCarthy, who has allied himself closely with Trump in the last two years, is working on the border wall bill by himself at this point, with no cosponsors. 1757

House Majority Leader Kevin McCarthy plans to introduce legislation this week that will fully fund President Donald Trump's proposed wall along the U.S.-Mexico border with a whopping .4 billion price tag, a spokesperson for the California Republican told CNN on Tuesday.The bill is still in the drafting process but is expected to be released within the next few days in the pro-forma session this week. The House remains in recess until mid-November, after the midterm elections, so the body would not consider the legislation for another month or so. Even with a Republican-controlled Capitol Hill and White House, any proposal to fully fund Trump's signature campaign pledge of a border wall would have a difficult pathway to passing both chambers of Congress, given the threshold for such legislation and the narrow margin of control in the Senate.The legislation comes as McCarthy is headed to the U.S.-Mexico border on Wednesday for a tour and briefing by the Department of Homeland Security and as the California congressman continues to push to succeed Speaker Paul Ryan when the Wisconsin Republican departs in January.Mccarthy is not the only House Republican to express interest in leading the caucus. Majority Whip Steve Scalise of Louisiana and House Freedom Caucus co-founder Jim Jordan of Ohio have talked about pursuing the top House GOP spot, and both are traditionally affiliated with the more conservative side of the caucus members. Scalise has said he would not run to lead the party if McCarthy does, but Jordan has already announced his intention to seek the position.McCarthy, who has allied himself closely with Trump in the last two years, is working on the border wall bill by himself at this point, with no cosponsors. 1757

In an election year, it probably comes as no surprise that the two most tweeted about people in the world this year were the two top presidential candidates.According to Twitter’s annual year-end review, President Donald Trump was the most-tweeted about person in 2020, one spot ahead of President-elect Joe Biden.The third-most tweeted about person was George Floyd, who died on Memorial Day while in the custody of Minneapolis police officers. His death sparked renewed nationwide protests and calls of police reform.Kobe Bryant, who died in a helicopter crash in January along with his 13-year-old daughter Gianna and seven others, was the fourth-most tweeted about person in 2020.Former President Barack Obama was the fifth-most tweeted about person in 2020.Meanwhile, the most liked tweet of 2020 was from the account of Chadwick Boseman on August 28, announcing the “Black Panther” star’s death. The tweet, which had 7.6 million Twitter likes, was the most-liked tweet in the history of the social media platform.Twitter said that #COVID19 was the most tweeted about hashtag in 2020. #StayHome made the list at No. 3.To see more about Twitter’s 2020 data, click here. 1181

If you're a night owl, you may want to consider spending your winters in northern Alaska.Utqiagvik, Alaska, formerly known as Barrow, experienced its last sunrise and sunset on Sunday for about two months.The town of about 4,000 people is now beginning its 65-day period of darkness, known as polar night.Polar night is a common term in places that don't experience sunrise for more than 24 hours, according to CNN meteorologist Judson Jones."This happens every year," Jones said. "If you live above the Arctic Circle, there will be a day when the sun sets for the rest of winter. The good news? It will return and then during the summer when it won't set for days."The northern third of Alaska lies above the Arctic Circle, the ring of latitude that encircles the frigid Arctic polar region.Although Utqiagvik is not the only Alaskan town to experience this phenomenon, it is the first one on the polar night location list because of how far north it is.For about one to two months, the residents of Kaktovik, Point Hope and Anaktuvuk Pass will also be without the sun. Their final sunsets will happen between late November and early December, according to CNN affiliate KTUU.The sun officially set at 1:43 p.m. Sunday in Utqiagvik, starting its 65-day hiatus from the town. It won't peek above the horizon again until January 23, 2019.The-CNN-Wire 1357