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WASHINGTON, Oct. 3 (Xinhua) -- Researchers at St. Michael's Hospital in Canada have discovered a new function for an enzyme that may protect against organ injury and death from anemia, according to a study appearing Monday in the U.S. journal of the Proceeding of the National Academy of Sciences.Researchers found that when people have anemia, neuronal nitric oxide synthase (nNOS) -- an enzyme in nerve cells that produces nitric oxide, an important signaling molecule in the body -- increases the body's ability to respond, adapt to low oxygen levels and makes the body more efficient in delivering oxygen to tissues. They also found that levels of nNOS in the brain increased in anemic mice, and that the mice without this enzyme die earlier, and with higher hemoglobin levels."Identifying this mechanism may lead to new therapies and approaches to improving outcomes for anemic patients," said Dr. Greg Hare, a researcher at the Li Ka Shing Knowledge Institute of the hospital and one of the lead investigators of the study.Anemia occurs when blood has a lower than normal number of red blood cells or hemoglobin -- an iron-rich protein that carries oxygen from the lungs and heart to the rest of the body. Cells need oxygen to survive and to produce energy for all bodily functions. The condition has many different causes including infection (malaria, HIV, parasites), nutritional deficiencies (iron, folate, B12), genetic mutations, pregnancy, trauma and surgical blood loss."This research will help us identify when an anemic patient is at greatest risk for injury and death when undergoing surgery," said Hare. "Research is underway to test these findings in humans."
WASHINGTON, Oct. 3 (Xinhua) -- Researchers at St. Michael's Hospital in Canada have discovered a new function for an enzyme that may protect against organ injury and death from anemia, according to a study appearing Monday in the U.S. journal of the Proceeding of the National Academy of Sciences.Researchers found that when people have anemia, neuronal nitric oxide synthase (nNOS) -- an enzyme in nerve cells that produces nitric oxide, an important signaling molecule in the body -- increases the body's ability to respond, adapt to low oxygen levels and makes the body more efficient in delivering oxygen to tissues. They also found that levels of nNOS in the brain increased in anemic mice, and that the mice without this enzyme die earlier, and with higher hemoglobin levels."Identifying this mechanism may lead to new therapies and approaches to improving outcomes for anemic patients," said Dr. Greg Hare, a researcher at the Li Ka Shing Knowledge Institute of the hospital and one of the lead investigators of the study.Anemia occurs when blood has a lower than normal number of red blood cells or hemoglobin -- an iron-rich protein that carries oxygen from the lungs and heart to the rest of the body. Cells need oxygen to survive and to produce energy for all bodily functions. The condition has many different causes including infection (malaria, HIV, parasites), nutritional deficiencies (iron, folate, B12), genetic mutations, pregnancy, trauma and surgical blood loss."This research will help us identify when an anemic patient is at greatest risk for injury and death when undergoing surgery," said Hare. "Research is underway to test these findings in humans."
RIO DE JANEIRO, Oct. 21 (Xinhua) -- Representatives from 120 countries attending the WHO's World Conference on Social Determinants of Health on Friday pledged to maintain investments in healthcare to reduce social gap.A statement adopted at the conference urged governments to maintain international collaboration and promote equal access to healthcare regardless of wealth.Brazilian Health Minister Alexandre Padilha said the economic woes in many countries cannot be a reason to "diminish" their social policies."The crisis cannot be an obstacle, instead it must be an opportunity to consolidate social policies," he said.Brazilian Foreign Minister Antonio Patriota said at the conference that health was an issue related to sustainable development, which will be discussed at the UN's Rio +20 Conference in 2012."The conference that ended today is an important step toward Rio +20," he said.
WASHINGTON, Nov. 22 (Xinhua) -- Long-term coffee consumption may be associated with a reduced risk for endometrial cancer, according to a study published online Tuesday in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.Edward Giovannucci, professor of nutrition and epidemiology at the Harvard School of Public Health, said that coffee is emerging as a protective agent in cancers that are linked to obesity, estrogen and insulin."Coffee has already been shown to be protective against diabetes due to its effect on insulin," said Giovannucci, a senior researcher on the study. "So we hypothesized that we'd see a reduction in some cancers as well."The researchers observed cumulative coffee intake in relation to endometrial cancer in 67,470 women who enrolled in the Nurses' Health Study. During the course of 26 years of follow-up, researchers documented 672 cases of endometrial cancer.Drinking more than four cups of coffee per day was linked with a 25 percent reduced risk for endometrial cancer. Drinking between two and three cups per day was linked with a seven percent reduced risk.A similar link was seen in decaffeinated coffee, where drinking more than two cups per day was linked with a 22 percent reduced risk for endometrial cancer.Giovannucci said that he hopes this study will lead to further inquiries about the effect of coffee on cancer because in this and similar studies, coffee intake is self-selected and not randomized.
BEIJING, Jan. 22 (Xinhua) -- On the eve of Spring Festival, people across China marked the last moments of the Year of the Rabbit with cheerful celebrations, while exchanging their wishes for a better and prosperous Year of the Dragon.Spring Festival, or Chinese New Year, falls on Monday but the week-long holiday started Sunday, with families, urban and rural as well as rich and poor, dining together and watching the year out in cheer.In a new community in Zhengzhou, capital of central China's Henan province, villagers relocated there for the nation's South-North Water Diversion project have their festival feasts paid for by the government."I've been buzzing around from office to office to get the festival allowances. Today is the third time money has been doled out before Spring Festival," said Lu Songtao, director of the resident committee of Jinyuan.The 60 households in Jinyuan are among the 330,000 people China has resettled for the central route of the massive water project, which aims to transport water from the Yangtze River to the country's drought-prone northern regions, including Beijing.Two month after bedding down in new homes with the help of government subsidies, villagers now wish their careers can also take off in the Year of the Dragon."There are many factories nearby, and I will start looking for a job right after the New Year, either in a battery plant or a food processing factory," said villager Liu Guizhi.In Wuhan, capital of Hubei province, sanitation workers who chose to stay on duty rather than be with their families during the festival ended up dining with the mayor."I'd like to thank you for a year's hard work that has kept the city beautiful," said Tang Liangzhi, mayor of Wuhan, at a banquet held on Saturday for 100 representatives of street cleaners.Though Spring Festival is an important family occasion for most Chinese, many cleaners could not leave their jobs as the week-long fireworks frenzy usually litters city streets with tonnes of cardboard and scraps of paper."I had been so busy today that I came to the banquet right from the street, with the my uniform on," said 51-year-old Yang Houjian."But I am deeply moved -- I feel my work is honored by the whole society," he said.This year's Spring Festival also brings a festive atmosphere to Xinjiang and Tibet, though celebrating the festival is not a tradition for many ethnic groups there. Young people, in particular, are mesmerized by the festival's "exotic" flavor."My friends from the Han community told me that it's their tradition to wear something red when their animal signs coincide with that of the year. So I bought a red bracelet as I'm a 'Dragon,'" said 23-year-old Hanati Kizihan, who is a Kazakh in Urumqi.Many households and institutions in Tibet have also put up national flags and portraits of Chinese leaders in honor of the national festival. On Sunday, a gigantic picture of China's central leaderships, represented by Mao Zedong, Deng Xiaoping, Jiang Zemin and Hu Jintao, was unveiled at the regional government building in Lhasa to celebrate the festival.