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LONDON (AP) — Oxford University says trials of a coronavirus vaccine that it is developing with pharmaceutical company AstraZeneca will resume, days after being paused due to a reported side-effect in a patient in the U.K. The university said in large trials such as this “it is expected that some participants will become unwell and every case must be carefully evaluated to ensure careful assessment of safety.” It said globally 18,000 people have received the vaccine so far. Oxford insisted that it is “committed to the safety of our participants.” Pauses in drug trials are commonplace. The Oxford-AstraZeneca vaccine is seen as one of the strongest contenders among the dozens of coronavirus vaccines being tested. 728
LOS ANGELES (AP) — Southern California residents faced with the loss of lives and homes in a huge wildfire also are grappling with the destruction of a vast swath of public lands that are popular destinations for hikers, horseback riders and mountain bikers.The Woolsey Fire has charred more than 83 percent of National Park Service land within the Santa Monica Mountains National Recreation Area, where officials announced Wednesday that all trails were closed."We understand that folks are curious about how their favorite park spots fared. We promise to share that ASAP," the park service tweeted, warning that the blaze was still active after burning for nearly a week.Three people have been found dead in fire zone, which spans 153 square miles (396 square kilometers).RELATED: Malibu residents frustrated by fire recoveryThe fire broke out Nov. 8 and quickly became one of the largest and most destructive in state history. Firefighters have made steady progress this week, getting it more than halfway contained, but warned many hotspots remain.A massive burn scar encompasses more than 30 square miles (80 square kilometers) within the recreation area that stretches from beaches to inland mountains straddling Los Angeles and Ventura counties. It's the largest urban national park in the nation, with more than 30 million visitors every year.Cyril Jay-Rayon, 52, watched the news with despair as flames engulfed what he called his "main playground" — a rugged area where he rode his mountain bike a few times a week. It includes the famous Backbone Trail, a 65-mile (104-kilometer) route that offers challenging terrain for bikers and hikers who are rewarded with soaring views of the Pacific Ocean."It's just devastating. Those trails are my sanity. It's where I ground myself," he said. "I love the city, but I also love how easy it is to get out into the wild."People share their recreation areas with wildlife, including 13 mountain lions tracked by biologists via GPS collars. Park officials said two of the big cats were unaccounted for. Four monitored bobcats also were believed to have survived, but their habitats were burned, the park service said.While the damage was still being assessed, officials confirmed that Paramount Ranch's "Western Town," a landmark film location dating to 1927 that included a jail, hotel and saloon, burned to the ground. The TV shows "Westworld," ''The Mentalist" and "Dr. Quinn, Medicine Woman" were among the productions that shot there.Officials took the loss of the film location especially hard, because it was a unique feature among all the national parks."It's so special to share the story of moviemaking that came out of Southern California," recreation area spokeswoman Kate Kuykendall said. "We're the only National Park Service site that interprets American film history."There's been an outpouring of public support for rebuilding the site, she said, adding that at least three homes of park employees were gutted.The fire also destroyed much of nearby Peter Strauss Ranch, which hosted performances by Johnny Cash and Willie Nelson in the 1950s and more recently was a wedding destination.Jay-Rayon, 52, said customers at the sports nutrition store he owns were coming to terms with the fact that it could be months or longer before they can ride or hike in their favorite wilderness areas again.Also charred was Cheeseboro Canyon, former ranchland featuring trails through rolling grasslands against the backdrop of peaks and canyons. After winter and spring rains, the area is awash in green, but vegetation quickly dries in the persistent sun, fading to yellow and then brown. Grasses and other plants were brittle in the weeks before the fire started.U.S. Interior Secretary Ryan Zinke was touring the Woolsey burn area Thursday.About 15 percent of the Santa Monica Mountains National Recreation Area is National Park Service land. The remainder is made up of private property, California State Parks and other conservation lands.___Follow Weber at https://twitter.com/WeberCM___Associated Press journalist Brian Melley contributed to this report. 4138
LOS ANGELES (CNS) - The U.S. Justice Department in Los Angeles announced today that it has obtained an additional .4 million for servicemembers whose vehicles were repossessed by Wells Fargo Bank in violation of federal law.Wells Fargo reached a million settlement with federal prosecutors last year over allegations it illegally repossessed more than 400 cars owned by members of the military without a court order.The settlement resolves alleged violations of the Servicemembers Civil Relief Act, which protects service members against certain civil proceedings that could affect their legal rights while they are in the service.The additional amount brings the total compensation under the settlement to more than .1 million and the total number of servicemembers eligible for relief to more than 860."The SCRA provides important protections and is intended to prevent unnecessary financial hardship for the brave women and men who serve in our armed forces," said acting U.S. Attorney Sandra R. Brown."Losing an automobile through an unlawful repossession while serving our country is a problem servicemembers should not have to confront. We are pleased that Wells Fargo is taking action to compensate these additional servicemembers as required under the settlement with the Justice Department."The settlement covers repossessions that occurred between Jan. 1, 2008, and July 1, 2015. The agreement requires Wells Fargo to pay ,000 to each of the affected military members, plus any lost equity in the vehicle with interest.Wells Fargo also must repair the credit of all affected soldiers.The agreement also requires Wells Fargo to pay a ,000 civil penalty to the United States and to determine, in the future, if any vehicle it is planning to repossess is owned by an active duty service member. 1823
LOS ANGELES (AP) — U.S. Customs and Border Protection says its officers at the Los Angeles-Long Beach ports complex recently seized more than 14,800 pairs of counterfeit Nike shoes in a shipment arriving from China.The agency says Wednesday that had the fake special edition and retro design shoes been real, the manufacturer's suggested retail prices would have totaled more than .2 million.The shoes were in two containers with contents declared as napkins.The agency says the shoes violated protected designs and trademarks for various versions of Nike's Air Jordan and Air Max shoes.Customs and Border Protection says collectors might pay between ,500 and ,000 for a legitimate pair of the shoes. 714
LOS ANGELES (AP) — Marge Simpson has advice for a lawyer with the Trump campaign: Do not name call. In a clip posted by Fox's animated series "The Simpsons," matriarch Marge chides the lawyer for comparing her voice to that of Kamala Harris. 250