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SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462

Senate Majority Leader Mitch McConnell will sit down Tuesday with 9/11 first responders on Capitol Hill, following comedian Jon Stewart's high-profile criticism of Congress and his plea for the extension of the September 11th Victim Compensation Fund, which is struggling to pay its current claims."I think we have momentum and I think we're going to challenge Mitch McConnell's humanity tomorrow," 9/11 first responder John Feal told CNN on Monday, confirming the meeting scheduled for Tuesday afternoon.Feal said the meeting had been in the works since before Stewart's emotional testimony on Capitol Hill two weeks ago, but plans had not formally come together until that week that the comedian and activist's impassioned plea went viral.Feal said on CNN's "New Day" on Tuesday that past meetings with McConnell did not go well because of their different views, but said he has an "open mind" about the upcoming meeting."I'm going to pray for the best, be prepared for the worst," Feal said.At issue is funding for the September 11th Victim Compensation Fund, which provides health care and services for 9/11 first responders. The current law, which was last renewed in 2015, expires next year and the fund's administrator says it doesn't have enough money to pay out all the current claims now. The new bill, that passed out of the House committee last week, does not call for a specific amount of funds but whatever sums necessary through 2090.At the time of its last renewal in 2015, Congress appropriated .6 billion to the fund, bringing the total appropriated amount of the fund over the years to .4 billion. The special master who administers the fund anticipates that total payouts for claims filed before the measure expires in 2020 could be far higher: .6 billion, if a current uptick in claims -- largely caused by an increase in serious illnesses and deaths -- continues.While there have been public commitments from both parties to ensure more money the fund is extended, the legislation seems at least weeks if not months away from final passage -- a timeline that is too slow for some of the funds' recipients and their advocates.One example: a retired NYPD bomb squad detective who testified about his 9/11-related medical issues alongside Stewart said last week he is now entering end-of-life hospice care."I'm now in hospice, because (there) is nothing else the doctors can do to fight the cancer," Luis Alvarez wrote in a Facebook post last week.Feal told CNN's "New Day" on Tuesday that "the longer we wait, the longer people suffer.""There are people sick and dying that are going to die in the very near future, that are going to leave their families in financial ruins," Feal said. "Mitch McConnell and the rest of the Senate ... need to sense our urgency, because these men and women in uniform and nonuniform, the people in lower Manhattan, they need this now, today, right now, yesterday, and it's going to be stressed today."Stewart, who has been fighting for 9/11 first responders' health benefits for years, testified on Capitol Hill earlier this month at a House subcommittee hearing over the legislation to fight for the funding to be extended immediately and he called out lawmakers for not attending the hearing."'Shameful," Stewart said, "It's an embarrassment to the country and it is a stain on this institution. And you should be ashamed of yourselves for those that aren't here. But you won't be, because accountability doesn't appear to be something that occurs in this chamber."Following Stewart's comments, lawmakers from both parties have vowed to extend the funding for the program."Every sick responder and survivor should be treated with the same dignity and compassion," said House Judiciary Chairman Jerry Nadler, a Democrat from New York whose committee unanimously advanced the legislation. "All responders and survivors, whether they got sick in 2015 or will get sick in 2025 or 2035, should be properly compensated. Congress must act to make that happen."In the days since his initial comments, Stewart has kept up the public pressure, focusing much of his criticism on McConnell as well as challenging him to meet with first responders as soon as possible, something McConnell has done before."Don't make them beg for it. You could pass this thing as a standalone bill tomorrow," Stewart said appearing on CBS' "The Late Show with Stephen Colbert." "If you're busy, I get it. Just understand, the next time we have war; or you're being robbed; or your house is on fire, and you make that desperate call for help, don't get bent out of shape if they show up at the last minute, with fewer people than you thought were going to pay attention, and don't actually put it out."McConnell pushed back in a Fox News interview, vowing to the fund would be fully funded and saying he could not understand why Stewart is the one "all bent out of shape" on the issue."Well, many things in Congress happen at the last minute. We never failed to address this issue and we will address it again," McConnell told Fox News. "I don't know why he is all bent out of shape. We will take care of the 9/11 compensation fund."McConnell dodged the question last week when asked by CNN if he would meet with 9/11 responders in response to Stewart's challenge, saying only, "I don't know how many times I can say we've never let 9/11 victims behind and we won't again."This will not be McConnell's first meeting with a group of first responders. Feal tells CNN they last met with McConnell in 2015 and 2010. McConnell's office did not comment, when asked by CNN about Tuesday's meeting.The bill now waits to be passed by the full House. House Majority Leader Steny Hoyer said it is their intention to take it up sometime before the August recess.After passing the House, which it is expected to do easily, the bill will be sent to the Senate for a vote.Senate Minority Leader Chuck Schumer, a New York Democrat, said last week he believes that Stewart's public pressure has "had some effect" on pressuring McConnell."By the end of Senator Mitch McConnell's meeting with these first responders tomorrow, he should commit to put the bill on the floor for a stand-alone vote immediately following House passage," Schumer said in a statement Monday. "We cannot tolerate any more delay." 6329

Sixteen US Marines were arrested Thursday for alleged involvement in various illegal activities ranging from human smuggling to drug-related offenses, according to a statement from the Marine Corps.The arrests took place in a dramatic fashion on Thursday morning at Camp Pendleton, California, during a battalion formation."Information gained from a previous human smuggling investigation precipitated the arrests," the statement said. "None of the Marines arrested or detained for questioning served in support of the Southwest Border Support mission."Eight other Marines were also questioned on their involvement in alleged drug offenses unrelated to today's arrests, the Marine Corps said. 704

Run: Exit the area and move away from danger.Hide: If escape is not possible, find a safe area to hide.Fight: This is an absolute last resort.https://t.co/Ow23ySe5gB— LSU (@LSU) August 20, 2019 205

Samples taken from at least one minibar at the Bahia Principe Hotel are being tested by the FBI as part of the agency's collaboration with Dominican Republic authorities, Ministry of Health communications director Carlos Suero said Wednesday.Suero added that an extensive collection of samples is taken by Domincan authorities when someone dies in a hotel room. Minibars are tested for bacteria and water from showers and sinks are examined, he said.The FBI is assisting with the toxicology tests of three of the nine Americans who have died in the Dominican Republic in the past year, he said.Last week the US Embassy announced the FBI involvement in toxicology analysis and said results might take up to 30 days.The spate of deaths has left many Americans wondering 780