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A final analysis of a COVID-19 vaccine candidate produced by Pfizer and BioNTech shows that the drug is 95% effective in preventing the coronavirus, and the companies say they hope to apply for Emergency Use Authorization within "days," the company reported Wednesday.The announcement is an improvement from an initial analysis released by the company just over a week ago that showed the drug to be 90% effective. Those results were released when it had been confirmed that 94 participants in the trial who received a shot had contracted COVID-19, and only 10% of those participants who contracted the virus had actually received the vaccine. Updated information now shows that 170 people who participated in the trial have contracted COVID-19, which crosses the threshold for final analysis. Of those participants, 162 received a placebo shot. Of the 20,000 participants who received the vaccine, just one has developed a severe case of COVID-19. The other seven people who received the vaccine and caught the virus are only experiencing mild symptoms.Pfizer also added that the vaccine has proven to be 94% efficient in older people — a welcome sign, given that the virus tends to present more severe symptoms in elderly patients.Pfizer's trial included about 40,000 participants, half of which received the vaccine, and the other half which received the placebo. The vaccine requires two shots, which need to be taken 28 days apart.The company added that there have been no safety concerns with the vaccine. In a randomized survey of 8,000 participants, only 2% reported suffering severe fatigue, and only 4% reported suffering severe headaches. Those who say they suffered side effects only experienced them briefly after vaccination.Wednesday's announcement means Pfizer is on track to shatter records for vaccine development, a process that typically takes several years.Pfizer and BioNTech already have their vaccine candidate in production, meaning it will be ready for distribution as soon as the Food and Drug Administration grants Emergency Use Authorization.Pfizer's announcement comes days after an initial analysis of a Moderna-produced vaccine was also shown to be 95% effective. Several other companies also have a COVID-19 vaccine in the works, something that health officials say is important for logistics and safety. 2347

A gunman who killed four people in Northern California rammed a pickup through a locked gate and marched onto the grounds of an elementary school, but he could not enter the classrooms, authorities say.He fired his rifle through windows and walls, and tried the doors, but the buildings at the Rancho Tehama Reserve school were secure.Only an outside bathroom was open, but it was empty. 395

A day after President Donald Trump and Democratic presidential nominee Joe Biden squared off in what proved to be a more civilized and substantive debate, both candidates will return to the campaign trail to deliver their final pitches to the American people.Biden will deliver remarks from his home state of Delaware on Friday afternoon — his first public appearance this week outside of Thursday's debate. Since last week, Biden has laid low, allowing surrogates like his running mate, Sen. Kamala Harris, and former President Barack Obama campaign for him as he focused on debate prep.Biden's remarks are currently scheduled to take place at 2:30 p.m. ET.Later Friday, Trump will continue his busy tour of swing states, as he makes multiple appearances in the key battleground state of Florida.Trump will first hold an afternoon rally at The Villages — one of the country's largest retirement communities. Retirees are a key demographic that Trump carried in 2016, but new polling from the AARP shows older Americans favor Biden by a slight margin.Later in the evening, Trump will hold a second rally in Pensacola, Florida.While Biden chose to eschew travel for debate prep this week, Trump made visits to several key battleground states, including Pennsylvania, Arizona and Georgia.Recent polls show that Biden leads Trump anywhere from 3 points to 10 points in the general election vote share. Polls also show that Biden leads Trump in most key swing states, but by a thinner margin.With election day 11 days away, many states have already seen a record numbers of early votes. 1590

A Canton, Ohio high school teacher has been indicted on multiple felony counts for allegedly engaging in sexual activity with students.Tiffany Eichler, 36, was charged with three counts of sexual battery, all third-degree felonies.Eichler is accused of having sex with three different students who attended McKinley High School in Canton while she was employed as a physical education teacher.Canton police interviewed Eichler on March 8 after they were notified by the director of school security. Eichler told police she was being blackmailed for money by students after having had sex with them, according to a police report.During the interview, Eichler told authorities she picked a student up near his house and the two engaged in sexual activity in her car. According to the report, Eichler went to the student's house later the same day and the two engaged in sexual activity in the basement. The report states that following the encounters, the student reached out to the teacher and asked for money to buy antibiotics.The student also told Eichler that his sister found out about their relationship and he needed money to keep her quiet, according to the police report. Police reports say Eichler allegedly had sexual contact with another student one day after school when she called him into her office before practice. Eichler allegedly engaged in sexual activity with a third student in the backseat of her car at an unknown park.Following the investigation, the school district released the following statement: 1578

A body found in Costa Rica has been identified as a Florida woman who went missing while she was on vacation, according to her family. The father and brother of Carla Stefaniak identified the body as the 36-year-old Tuesday night.During an exclusive interview with WFTS, Stefaniak's father, Carlos, said his heart shattered when he saw her body.Costa Rica's Judicial Investigation Agency (OIJ) said an autopsy performed on her body showed that she had stab wounds around the neck and extremities and blunt-force trauma to the head.Family friend, Greg Zwolinsky, who is with them in Costa Rica, said he wants everyone to remember Stefaniak based on the radiance of her personality that is portrayed in pictures of her smiling. 783

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