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SAN DIEGO (KGTV) — UC San Diego researchers are testing a technology that's been in development for more than a decade to fight the coronavirus.In lab experiments, "nanosponges" covered in human lung cell membranes and immune cell membranes were found to attract and neutralize the SARS-CoV-2 virus in cell culture, according to a UCSD release. This caused the virus to lose about 90% of infectivity, or its ability to hijack cells and reproduce.The tiny sponges are designed to impersonate and protect healthy cells by soaking up harmful pathogens and toxins, according to Liangfang Zhang, a nanoengineering professor at the UC San Diego Jacobs School of Engineering. RELATED: San Diego company's COVID-19 test gets emergency approvalFor example, the nanoparticle covered in membranes from cell types the virus is known to invade latch on to the virus. This prevent the virus from then entering an actual human cell."Traditionally, drug developers for infectious diseases dive deep on the details of the pathogen in order to find druggable targets. Our approach is different. We only need to know what the target cells are. And then we aim to protect the targets by creating biomimetic decoys," said Zhang.While Zhang has spent the last 10 years developing the technology, his lab turned to using the nano-particle to fight the coronavirus when the pandemic hit.RELATED: Scripps Research's antibodies study shows signs of success against coronavirusNow, the first data on the technology's ability to battle the virus is being released after testing by researchers at Boston University."Another interesting aspect of our approach is that even as SARS-CoV-2 mutates, as long as the virus can still invade the cells we are mimicking, our nanosponge approach should still work. I’m not sure this can be said for some of the vaccines and therapeutics that are currently being developed," said Zhang.UCSD researchers will test the nanosponges’ effectiveness in animal models in the next few months and are moving as fast as possible to eventually test the technology in humans. RELATED: Startup creates mobile COVID-19 testing clinic on wheelsNanosponges have a massive amount of testing ahead before they make it to human tests, Zhang said."I see potential for a preventive treatment, for a therapeutic that could be given early because once the nanosponges get in the lung, they can stay in the lung for some time," Zhang said. "If a virus comes, it could be blocked if there are nanosponges waiting for it."(Read more about the study and nanosponges here.) 2562

SAN DIEGO (KGTV) - While homes in California built after the mid-1970’s meet most seismic requirements, older homes can require significant upgrades to withstand a major earthquake. Moses Govea with Turnkey Contractors says the are required to upgrade older homes when they do renovations. It includes adding galvanized bolts to the foundation, forming sheer walls and adding metal braces to certain connection points. Geologist Pat Abbott said while viewing footage from the recent quake in Mexico he noticed the collapsed buildings likely were missing up-to-date joinery between the floors and walls. “As long as [the floor and walls] move as a unit, the structure is intact,” he said. The City of San Diego offers resources to check your home on their website. They also have information on renovations for unreinforced masonry buildings, typically built before 1933. 903

SAN DIEGO (KGTV)-- A man was shot in the leg Friday morning in downtown San Diego's East Village neighborhood by a man who approached him asking to buy drugs, San Diego police said.The shooting was reported around 4:40 a.m. on 16th Street between K Street and Imperial Avenue, just west of Interstate 5.According to police, a man who looked to be in his 20s approached the victim on 16th Street, and walked off when said the victim replied that he didn’t sell drugs.About 20 minutes later, the same man returned and confronted the victim, pulled out a handgun and shot him in the leg.The victim was taken to a hospital and is expected to survive.The gunman was described as a 5-foot-8 black man in his 20s with a heavy build and curly black hair. At the time of the shooting, he wore a blue jacket and gray pants.Anyone with information about the shooting is urged to call San Diego Police Department's central division at 619-744-9500. 944

SAN DIEGO (KGTV) — What's better than a night full of laughs? Perhaps one you didn't really see coming in the first place."Don't Tell Comedy" will host a series of secret stand-up comedy shows in North Park, La Jolla, Pacific Beach, and Encinitas from Aug. 16 - 18.The premise of exactly what it sounds like: Guests buy their tickets online for a given show, but don't learn of the location until 12 p.m. on the day of the show. According to organizers, the venue quite literally can happen anywhere: Backyards, living rooms, a local business, steam ships, anywhere.MAP: San Diego tiki bars to celebrate classic Polynesian PopThe lineup of comedians who will be performing is also kept a secret until they're brought on stage. And you never know who will show up. Past headlining comedians have included Ali Wong, Todd Glass, Iliza Shlesinger, Bryan Callen, and several other comedy heavyweights.Tickets begin at for general admission and for a guaranteed seat. Events are also BYOB, so no need to worry about a two-drink minimum. Organizers say they do not conduct any transactions at the shows.Tickets are available online here. 1146

SAN DIEGO (KGTV) - Tucked within City Heights are natural wonders along a winding system of trails and walkways.But many of those scenes of nature go unnoticed. Not by intention, though.Justin Boone, owner of Burly and the Bean, noticed visitors coming into his coffee shop looking for a way to connect to the nearby canyons and beyond.RELATED: Mariachi dances above Interstate 5 in San DiegoThe trend got Boone thinking. So he began leading hikes once a week through the canyons for the outdoorsy, java-hungry customers, and anyone in between."I decided to do a user-friendly map and started doing the canyon hikes," Boone told 10News anchor Ariel Wesler. Wesler and 10News Chief Photographer Steve Reusch joined Boone on a hike for a look at how he's bringing the local community together. 824