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SAN DIEGO (KGTV) — Sunday, San Diego County health officials reported 568 new coronavirus cases and three new community outbreaks, including one at a preschool.The county's new cases were out of 8,943 reported tests, a 6% positive rate, and brought the region's total to 23,682 cases.The three new community outbreaks were reported in a restaurant/bar, in a manufacturing facility, and in a preschool, the county said. In the past week, the county has reported 16 community outbreaks — more than double the trigger of seven community outbreaks in seven days.SAN DIEGO COVID-19 CASE TRACKERThe county has said in the past it will not report where the community outbreaks are located, but says that in the past week there have been outbreaks reported:7/12: 07/13: 37/14: 47/15: 17/16: 27/17: 37/18: 3The three outbreaks reported on July 17 included one in a restaurant/bar, one in a gym, and one in a government setting; and the two on July 17 were both restaurants, according to the county.No new deaths from the virus were reported on Sunday, keeping the county's death toll at 478.Out of the county's cases, 9.3% have needed hospitalization. The county adds that 2.4% of all cases and 25.9% of hospitalized cases had ended up in the ICU.The county continues to fall short on case rate (157.2) and case investigation (7%) triggers. San Diego's case rate trigger is greater than 100 cases per 100,000 people over 14 days, while the trigger for investigations is 70% or less within 24 hours of notification over seven days.See the county's updated triggers dashboard here.San Diego County has remained on the state's monitoring list since July 3. 1652

SAN DIEGO (KGTV) — The Centers for Disease Control and Prevention announced Thursday it is extending a ban on cruise ships operating in U.S. territory through September.The ban was set to end next week, but the agency extended the ban as coronavirus cases rise in 40 states.Florida and California, where many cruises originate or end, both set records for new daily COVID-19 cases recently.RELATED: As cruise ships idle, San Diego region lost up to millionThe CDC says the ban on cruise ship operations will be in effect until, "the expiration of the Secretary of Health and Human Services’ declaration that COVID-19 constitutes a public health emergency," "the CDC Director rescinds or modifies the order based on specific public health or other considerations," or Sept. 30.Some cruise lines had already canceled scheduled sailings until Sept. 15 over ongoing discussions with federal officials on how to restart business safely, the Associated Press reported.The Port of San Diego estimates that each cruise ship that visits San Diego generates about 0,000 in regional economic impact, including local shopping, restaurant businesses, and other expenses.Nearly 30 cruises were canceled due to the pandemic, costing about million in lost revenue for the Port of San Diego alone, according to Brianne Page, a public information officer for the Port of San Diego. The cost to regional economic impact could be as high as million.The Associated Press contributed to this report. 1499

SAN DIEGO (KGTV) — Target is rolling out more locations for customers to take advantage of drive-up shopping.Target's Drive Up service is expanding to more customers who place orders through the Target mobile app. The free service then delivers a customer's order to their car in under two minutes.Currently, the service is available in more than 1,100 Target locations, including in San Diego County:South Park (3030 Grape St., San Diego)Mission Valley (1288 Camino Del Rio N., San Diego)Lemon Grove (3424 College Ave., San Diego)National City Plaza Bonita (3060 Plaza Bonita Rd., National City)Grossmont (5500 Grossmont Center Dr., La Mesa)Chula Vista East (910 Eastlake Pkwy, Chula Vista)Rancho San Diego (2911 Jamacha Rd., El Cajon)El Cajon (250 Broadway, El Cajon)Mira Mesa (8251 Mira Mesa Blvd., San Diego)Santee (9846 Mission Gorge Rd., Santee)Poway (14823 Pomerado Rd., Poway)San Diego Del Sur (17170 Camino Del Sur, San Diego)Escondido South (280 E Via Rancho Pkwy, Escondido)Escondido (1280 Auto Park Way, Escondido)Vista South (3150 Business Park Dr., Vista)Vista (1751 University Dr., Vista)Oceanside (2255 S El Camino Real, Oceanside)Rancho California(29676 Rancho California Rd., Temecula)San Clemente (990 Avenida Vista Hermosa, San Clemente)Murrieta (41040 California Oaks Rd., Murrieta)“With this expansion of Drive Up, we’re continuing the momentum from our coast-to-coast roll out last year to bring even more guests their fastest Target Run yet,” Dawn Block, Target's senior vice president of digital, said in a release. “Guests love the ease and convenience of these parking lot pickups—in fact, it’s our top-rated fulfillment service.”Target's move comes as more retailers opt to offer curbside pick-up for orders, including the company's competitor Walmart, which also offers drive-up delivery for orders made the same day. 1854

SAN DIEGO (KGTV) - The coronavirus outbreak is filling many with fear, anxiety and depression. To cope with these feelings, 10News spoke with licensed psychologist Dr. Michelle Carcel on strategies to get through the chaos."Evolutionarily we are not built for quick adaptation." Carcel said, that's why the reptilian part of our brain is freaking out. "One of my favorite sayings, it's not mine but I use it all the time, is relax nothing is in our control."READ RELATED: San Diego County libraries go digital to fight spread of coronavirusCarcel said mindfulness activities like yoga and meditation bring you into the moment and activate the parasympathetic nervous system, to calm the brain.Her first piece of advice for coping with all these changes to your daily life is to set a schedule. A schedule for you and any kids will bring back a sense of normalcy, and comfort.If you're feeling down, or isolated, find a furry friend. Adoptions and fostering is up in San Diego.RELATED: Where to get help amid coronavirus"Take time to walk your dog, play with your cat. They relieve stress quite a bit, so that's good," Carcel said smiling.Checking on a friend during this time of isolation is also important. "That is actually one of the worst times for folks who are specifically suffering from domestic violence concerns. We must take this incredibly seriously," Carcel added. She urges anyone who needs help to call the Crisis Line at 888-724-7240.Another serious issue we're facing is financial stress, many losing their job from the shut down. Carcel says while these are unprecedented times, we will endure, "here's the thing, humans are resilient. We have made it through a bunch of different, terrible things in our evolutionary process and we must remember that."She advises enjoying the time we have inside, by indulging in a book, playing a board game, or calling someone you love."Just surf the wave, we're going to make it through," she said.OPTUM has a free 24/7 helpline for anyone who needs emotional support, you can call 866-342-6892. 2060

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

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