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WASHINGTON, April 3 (Xinhua) -- Scientists have confirmed that metabolic syndrome, a constellation of conditions that increases the risk of heart disease and diabetes, may also increase the risk of the two most common types of liver cancer, according to data presented at the American Association for Cancer Research's 102nd Annual Meeting 2011, held in Orlando, Florida on April 2-6.Katherine McGlynn, a senior investigator at the National Cancer Institute, said approximately one-third of the U.S. population has metabolic syndrome, which is defined as the co-occurrence of at least three of the following five conditions: raised blood pressure, elevated waist circumference, low HDL or "good" cholesterol, raised triglyceride levels and raised fasting plasma glucose levels.According to McGlynn, persons with these conditions may be at increased risk of developing hepatocellular carcinoma and intrahepatic cholangiocarcinoma.For the current study, researchers identified 3,649 cases of hepatocellular carcinoma and 743 cases of intrahepatic cholangiocarcinoma. They compared the medical history of these patients with the medical histories of 195,953 cancer-free adults.Statistical analyses showed that the persons with liver cancer were significantly more likely than cancer-free persons to have a prior history of metabolic syndrome: 37.1 percent of patients with hepatocellular carcinoma had pre-existing metabolic syndrome, as did 29.7 percent of patients with intrahepatic carcinoma; only 17.1 percent of the cancer-free adults had metabolic syndrome.Liver cancer incidence has been rising since the 1980s in the United States. The factors related to the increase are not well understood. "A lot of attention has focused on viral risk factors, but a significant part of the increase may be due to metabolic syndrome, as well as to diabetes and obesity," said McGlynn."The prognosis for liver cancer is only marginally better than the prognosis for pancreatic cancer, with a five-year survival of approximately 10 percent," she said. "Prognosis is more favorable, however, when liver cancers are diagnosed at early stages when they are small and localized to the liver."
TOKYO, May 21 (Xinhua) -- Japanese Economy, Trade and Industry Minister Banri Kaieda met with visiting Chinese Commerce Minister Chen Deming in Tokyo Saturday and agreed the two countries will promote bilateral trade to assist Japan's recovery after the March 11 quake and tsunami.Chen, who accompanied Chinese Premier Wen Jiabao to Japan, told Kaieda that China will offer "as much cooperation as possible to help Japan's reconstruction" by providing necessary supplies.Kaieda said Japan will strive to restore production and supply chain disrupted by the disasters as soon as possible.The two sides said they will conduct various investment and trade activities to strengthen cooperation and personnel exchange, and facilitate the smooth flow of bilateral trade so as to promote sustainable development.The two ministers signed a document on expanding bilateral economic and trade cooperation. They also reaffirmed that free and open trade will help Japan's reconstruction efforts.

WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.
BEIJING, Jan. 30 (Xinhua) -- China hoped Egypt could restore social stability and normal order at an early date, Foreign Ministry spokesman Hong Lei said Sunday."China has been closely watching the development of the situation in Egypt," Hong said when asked to comment on the ongoing turmoil in the country."Egypt is a friendly country with China, and we hope Egypt could restore social stability and normal order at an early date," he said.
LONDON, March 15 (Xinhua) -- The moon would be in a "super position" on Saturday, which makes it a "supermoon" and the web is awash with myths about its implications such as connection to recent earthquakes, but that's not the case according to British experts.Technically the so-called "supermoon" means that the moon would be in its perigee, the closest point to earth in its orbit on March 19, and on top of that, it would also be a full moon at the same time.The massive earthquake in Japan just fueled the speculation that the gravitational pull of the "supermoon" will bring chaos to the Earth, such as earthquakes and volcanic activities.But "there is little that is special about perigee on March 19," said Dr. Robert Massey, deputy executive secretary of the Royal Astronomical Society. He said the moon will be around 360,000 km from the earth on that day, but this has happened at least 15 times during the last 400 years."There is no reason whatsoever to believe that there is a connection between the so-called 'supermoon' and the recent earthquake," Massey told Xinhua. "There are also no other 'abnormal' phenomena connected with a 'supermoon' other than the high tides that we experience twice every month."Massey was echoed by Dr. Bruce Malamud, a geophysicist in the Department of Geography at King's College London, who that: "A supermoon will not be able to actually influence at all the internal workings of our Planet Earth, as there is so much momentum and mass already stored up, that the actual effect is negligible.""The earthquake took place a full 8 days before the 'supermoon' meaning that the tidal forces exerted by the moon and sun together were near their minimum rather than maximum level, directly contradicting the fearmongers," said Massey.Calling the "supermoon" claims "bogus science," he questioned the motives of those who made such claims on the day that thousands of people died in a severe earthquake and the ensuing tsunami.
来源:资阳报